Muscle Protein Synthesis Clinical Trial
— APREOfficial title:
The Effects Potato Protein on Rates of Myofibrillar Muscle Protein Synthesis in Young Women
Verified date | March 2020 |
Source | McMaster University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study will investigate the effects of potato protein on muscle protein synthesis over a short-term (a few hours after eating) and longer term (after two weeks of unilateral resistance exercise). Young women will be randomized to received potato protein supplementation or placebo in addition to their usual diet. Muscle biopsies will be taken and the participants will drink doubly labelled water to allow for the measurement of protein synthesis over time.
Status | Completed |
Enrollment | 24 |
Est. completion date | June 6, 2019 |
Est. primary completion date | June 6, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 29 Years |
Eligibility |
Inclusion Criteria: - meet the age requirements - Female sex Exclusion Criteria: - Significant loss or gain of body mass in the past 6 months (>2 kg) - Regular use of: non-steroidal anti-inflammatory drugs - History of chronic disease - Current or recently active or remised cancer - Infectious disease; and/or gastrointestinal disease - Consuming a vegetarian or vegan diet = Any condition or injury that would preclude them from participating in resistance exercise |
Country | Name | City | State |
---|---|---|---|
Canada | Ivor Wynne Centre | Hamilton | Ca-on |
Lead Sponsor | Collaborator |
---|---|
McMaster University |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Muscle protein synthesis | Myofibrillar protein synthesis via measurement of deuterated (doubly) labeled water | 17 days | |
Secondary | Protein expression | Western blot analysis to determine total protein expression of the proteins involved in the muscle protein synthesis pathway | 17 days |
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