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Mitral Valve Disease clinical trials

View clinical trials related to Mitral Valve Disease.

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NCT ID: NCT03893578 Not yet recruiting - Heart Failure Clinical Trials

The Conveyor Study

Start date: April 2019
Phase: N/A
Study type: Interventional

To demonstrate that the Conveyor System can safely provide left ventricular access to deliver the SAPIEN 3 (Edwards Lifesciences, Irvine, California) transcatheter heart valve in patients who have been diagnosed with prior mitral valve replacement or repair (failing bioprosthetic mitral valve) who are candidates for mitral valve-in-valve procedure.

NCT ID: NCT03859102 Recruiting - Clinical trials for Coronary Artery Disease

Enhanced Recovery After Cardiac Surgery

ERAS
Start date: December 17, 2018
Phase: N/A
Study type: Interventional

Enhanced Recovery Protocols (ERPs or bundles) have been established in many surgical specialties (such as colon cancer and orthopaedic joint surgeries) for several years in hospitals worldwide. The principles of Enhanced Recovery Protocols are those of early mobilization and restoration of normal function as soon as possible after surgery. These principles are achieved by use of alternate pain control regimens and removing invasive lines and drains as soon as possible. The benefits of ERPs are improved patient experience, earlier return to normal function and reduced length of stay. Enhanced recovery protocols for cardiac surgery have been published by the Enhanced Recovery After Cardiac Surgery Society. The current study will investigate whether it is possible to utilise ERP bundles in the population of cardiac surgery patients at James Cook Hospital, with a view to rolling out a full ERP service. Secondary study outcomes will be patient-centred, including; pain scores, nausea and vomiting rates and time taken to return to normal function.

NCT ID: NCT03812848 Completed - Atrial Fibrillation Clinical Trials

Clinical Pharmacist-led Inpatient Anticoagulation Stewardship Program

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

This study aims at evaluating the implementation of clinical-pharmacist-led anticoagulation stewardship program in Egyptian tertiary hospital to promote a culture of safety around anticoagulants.

NCT ID: NCT03697941 Completed - Clinical trials for Mitral Valve Disease

Percutaneous Plug-based Arteriotomy Closure Device Use in Minimally Invasive Mitral Valve Surgery

Start date: February 2016
Phase:
Study type: Observational

A single-center prospective study. Patients undergoing minimally invasive mitral valve surgery between February 2016 and December 2018 at the Karolinska University Hospital in Stockholm, Sweden are eligible. Femoral cannulation was performed either with surgical cut-down and arterial puncture under direct vision or percutaneously with planned percutaneous arteriotomy closed using a plug-based arteriotomy closure device (MANTA, Essential Medical Inc., Malvern, Pennsylvania). Data regarding preoperative clinical characteristics and operative details were obtained by medical records review and from the Swedish Web system for Enhancement and Development of Evidence based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) electronic data collection platform.

NCT ID: NCT03661398 Active, not recruiting - Clinical trials for Mitral Regurgitation

Caisson Transcatheter Mitral Valve Replacement (TMVR)

INTERLUDE
Start date: July 20, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the safety and performance of Transcatheter Mitral Valve Replacement (TMVR) system for the treatment of severe, symptomatic mitral regurgitation (MR).

NCT ID: NCT03609931 Not yet recruiting - Clinical trials for Mitral Regurgitation

Patient Specific Mitral Valve Modeling for Surgical Planning and Training

Start date: July 2018
Phase:
Study type: Observational

Mitral valve disease is a common pathologic problem occurring in approximately 2% of the general population but climbing to 10% in those over the age of 75 in Canada[1]. This project has three primary goals all of which will positively affect cardiac patient care. 1) Create patient specific MV models for complex repairs that will allow surgeons the opportunity to practice the repair. 2) Potentially predict the outcomes following minimally invasive repair techniques such as transcatheter treatments (e.g., MitraClip). 3) Provide a model to train individuals on mitral valve repair techniques.

NCT ID: NCT03592485 Completed - Postoperative Pain Clinical Trials

ESP vs ESP With PECS

Start date: June 28, 2018
Phase: Phase 4
Study type: Interventional

Patients scheduled for minimally invasive mitral valve repair. Each patient will be treated with intravenous (i.v.) oxycodone - patient-controlled analgesia (PCA). Patients will be allocated to one of the groups: erector spinae plane (ESP) block or EPS with pectoral fascia (PECS) block.

NCT ID: NCT03587688 Recruiting - Clinical trials for Mitral Valve Disease

Registry for Mitral Valve Surgery at Department of Cardiac Surgery University Hospital of Basel/ Switzerland

Start date: April 28, 2018
Phase:
Study type: Observational [Patient Registry]

A registry is installed to collect (pre-, intra- and postoperative) data on patients undergoing mitral valve surgery at the Department for Cardiac Surgery of Universitätsspital Basel/ Switzerland since 2009. Retrospective data (since 2009) as well as prospective data are included in this ongoing registry to analyse the development of mitral valve surgery at the Department of Cardiac Surgery University Hospital of Basel/ Switzerland.

NCT ID: NCT03574311 Recruiting - Clinical trials for Coronary Artery Disease

Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery

PREFER-CABG
Start date: October 2, 2018
Phase: Phase 4
Study type: Interventional

This study evaluates the efficacy and safety of single dose preoperative ferric carboxymaltose in the prevention of postoperative infections and blood transfusions in patients scheduled for cardiac surgery. Half of the patients will receive ferric carboxymaltose and half of the patients physiological saline solution as placebo.

NCT ID: NCT03539458 Active, not recruiting - Clinical trials for Cardiovascular Diseases

Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification

Start date: October 10, 2018
Phase: N/A
Study type: Interventional

This study is a prospective, single-arm, multi-center feasibility clinical study of the Tendyne Mitral Valve System for the treatment of eligible subjects with symptomatic, severe mitral regurgitation and severe mitral annular calcification (MAC). Subjects satisfying the study inclusion/exclusion criteria will undergo a procedure to implant the Tendyne mitral valve replacement device.