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Insulin Resistance clinical trials

View clinical trials related to Insulin Resistance.

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NCT ID: NCT03576703 Completed - Inflammation Clinical Trials

Sugar-sweetened Beverages Influence Benefits of Exercise in Overweight Adults

Start date: October 24, 2014
Phase: N/A
Study type: Interventional

The objective of this study was to determine how metabolic and inflammatory effects of physical exercise in overweight individuals are altered when sugar-sweetened beverages (SSB) are consumed after physical exercise. A randomized, controlled crossover trial was performed in which participants performed exercise with and without the ingestions of SSB during exercise or a non-exercise control condition to evaluate metabolic and inflammatory responses one day after the exercise and or SSB treatment.

NCT ID: NCT03561363 Completed - Insulin Sensitivity Clinical Trials

The Effect of 6 Weeks Saturated and Polyunsaturated High-Fat Diets on Insulin Sensitivity and Health Parameters

Start date: August 2014
Phase: N/A
Study type: Interventional

The aim of the intervention is to gain insight into the long term effect of dietary fatty acid quality on insulin sensitivity and health parameters in healthy men. Whole body and peripheral insulin sensitivity were measured, together with analyses of plasma hormones and metabolites. The plasma proteome was also analyzed. Molecular adaptations in skeletal muscle and adipose tissue were subject for investigation. Furthermore, gut microbiota population number and diversity will be analyzed from faeces samples obtained before and after the intervention.

NCT ID: NCT03556410 Completed - Obesity Clinical Trials

Sleep, Exercise and Insulin Sensitivity

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Insufficient or disrupted sleep, lack of physical activity and poor diet are linked with obesity and are now potential targets to combat obesity. Sleep related issues have become more important as people have been able to work, socialize, and use electronic devices outside of daylight hours. This has also altered how we eat and how we exercise. All of these factors can cause the body to not handle glucose (sugar) well resulting in insulin resistance. In time this could lead to type 2 diabetes.

NCT ID: NCT03527641 Completed - Stress Clinical Trials

United for Health: Type 2 Diabetes Prevention in Latino Teens

UNITED
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

This study pilots the feasibility and acceptability of a family-based lifestyle intervention for decreasing diabetes risk called "Salud sin Barreras" (meaning, "Health without Barriers") delivered in the community to Latino teens at risk for type 2 diabetes. This program combines traditional lifestyle intervention to change eating and physical activity with learning mindfulness-based stress reduction tools. We also are exploring how Salud sin Barreras lowers stress and improves insulin resistance in Latino teens, as compared to lifestyle-only intervention, the "La Vida Saludable" (meaning, the Healthy Living Program; HeLP).

NCT ID: NCT03527446 Completed - Obesity Clinical Trials

Acute and Chronic Metabolic Flexibility in Individuals Living With Obesity: The i-FLEX Study

i-FLEX
Start date: July 3, 2018
Phase: N/A
Study type: Interventional

Regular exercise is a cornerstone in the prevention and the management of cardio-metabolic risk factors. Some of the beneficial effect of exercise training occurs through metabolic flexibility' enhancement. Metabolic flexibility is the ability to respond or adapt to conditional changes in metabolic demand, and previous literature has shown that individuals living with obesity have an impaired metabolic flexibility compared to lean individuals. However, there is a lack of empirical evidence on the impact of sprint interval training on metabolic flexibility and whether this translates into clinically meaningful outcomes. This study will evaluate the impact of 4-week sprint interval training in normal weight individuals as well as individuals living with obesity on acute and chronic metabolic flexibility, irisin secretion and insulin sensitivity.

NCT ID: NCT03527290 Completed - Insulin Resistance Clinical Trials

Dietary Approaches for Cardiometabolic Health

DACH
Start date: January 15, 2018
Phase: N/A
Study type: Interventional

This pilot study aims to recruit 30 adults with abdominal obesity, without major chronic disease, and test whether clinical dietary advice that is solely focused on the timing of eating (time restricted eating), has an effect on cardiometabolic health compared to standard dietary advice for cardiometabolic health, which is focused on content. The goal of this pilot study is to develop and hone dietary counseling approaches for time restricted eating for RD's in a clinical practice paradigm, and collect data on testing this intervention compared to standard dietary counseling approaches for cardiometabolic health.

NCT ID: NCT03527277 Completed - Metabolic Syndrome Clinical Trials

Orange Juice And Sugar Intervention Study

OASIS
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The objectives of this proposal are to address the gaps in knowledge regarding the metabolic effects of consuming orange juice, the most frequently consumed fruit juice in this country, compared to sugar-sweetened beverage.

NCT ID: NCT03525171 Completed - Clinical trials for Growth Hormone Deficiency

Evalutation of Insulin Sensitivity Through Hyperinsulinemic Clamp in Children With GH Deficiency

clamp-GHD
Start date: January 1, 2014
Phase: N/A
Study type: Interventional

Data about the impact of growth hormone treatment on insulin sensitivity in children are quite controversial, due to the different surrogate indexes that have been used, like Homa-IR, QUICKI, ISI-Matsuda or adipokine levels. The investigators aimed to evaluate insulin sensitivity through the euglycemic hyperinsulinemic clamp, considered the gold standard technique, in children affected by growth hormone deficiency and to compare the M-value with the most commonly used surrogate indexes of insulin sensitivity.

NCT ID: NCT03520569 Completed - Insulin Sensitivity Clinical Trials

Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults

EJB050
Start date: February 4, 2019
Phase: Early Phase 1
Study type: Interventional

The investigators are studying the effects of Hyperglycemia on vascular function and insulin sensitivity on healthy adults

NCT ID: NCT03512665 Completed - Insulin Resistance Clinical Trials

Evaluation of the Impact of a Nutritional Supplement Made of Vegetable Oils in People at Risk of Diabetes

Start date: April 7, 2018
Phase: N/A
Study type: Interventional

Metabolic and cardiovascular diseases are the first cause of morbidity and mortality throughout the world, including Latin America and Colombia. Asymptomatic elevations of blood glucose, insufficient response to normal insulin concentrations (called insulin resistance), overweight and obesity can cause severe damage to body organs, leading to complications and even death. Worryingly, the prevalence of prediabetes is on the rise and efforts in public health policies made to contain this epidemic have had a very limited impact. This has prompted an intense search for non-pharmacological interventions. One of the most promising areas is research on "nutraceuticals", foods capable of positively impacting risk factors. However, there are insufficient nutritional or supplementary alternatives to favorably impact carbohydrate metabolism and cardiovascular risk factors in individuals at risk of diabetes. This project will evaluate the effects of the administration of a dietary supplement composed of vegetable oils. The fat composition of these oils is likely to impact positively on the metabolic profile of subjects at risk of diabetes and cardiovascular conditions.