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Infarction clinical trials

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NCT ID: NCT06186713 Completed - Clinical trials for Pulmonary Hypertension

Pulmonary Hypertension on Prognosis of Acute Myocardial Infarction Patients With Reduced Left Ventricular Function

STIMULATE
Start date: March 30, 2023
Phase:
Study type: Observational

Pulmonary hypertension (PH) has a negative effect on acute myocardial infarction (AMI) patients and appears to be closely associated with reduced left ventricular function. However, its impact on AMI patients with reduced left ventricular function remains unclear. This retrospective study included AMI patients with reduced left ventricular function to investigate the prognostic value of PH in this specific type of patient. Meanwhile, a nomogram would be established basing on the identified independent risk factors, hoping to provide a novel risk stratification for them.

NCT ID: NCT06155045 Completed - Clinical trials for Coronary Artery Disease

Comparing a New Technique of Combining Carbon-dioxide With Electrocautery With Usual Technique of Stand-alone Electrocautery for Taking Down Left Internal Mammary Artery for Coronary Artery Bypass(CABG)

CABG
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to compare the efficacy of a new harvesting technique for an arterial conduit(LIMA - Left Internal Mammary artery) in patients undergoing Coronary artery bypass grafting. The researcher will compare the 1. Time taken to harvest the artery 2. Flow of blood between the two techniques

NCT ID: NCT06059079 Completed - Clinical trials for Acute Myocardial Infarction

Using Higher Cut-off Values to Diagnose Acute Myocardial Infarction in Patients With Elevated Hs-cTnT Concentrations

Start date: January 1, 2015
Phase:
Study type: Observational

High-sensitive cardiac troponin T (hs-cTnT) is a cornerstone for diagnosing acute myocardial infarction (AMI). However, it is often challenging to diagnose AMI in patients with elevated hs-cTnT before a rise or fall of hs-cTnT can be observed. The elevations of hs-cTnT are caused not only by AMI, but also by other cardiac or even non-cardiac diseases. Thresholds above the 99th percentile have been proposed to improve the specificity and to accelerate the rule in of myocardial infarction. This study aimed to find a more accurate cut-off value to rule in AMI in patients with elevated hs-cTnT.

NCT ID: NCT06034054 Completed - Clinical trials for Coronary Artery Disease

Acute Coronary Syndrome and Nurse Counselling

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to examine in patients with acute coronary syndrome. The main questions it aims to answer are: - Does nurse counseling affect quality of life? - Does nurse counseling affect functional capacity? - Does nurse counseling affect knowledge, attitudes and beliefs about syndromes? Participants will be trained using the training booklet, and nursing counseling will then be provided for six months. If there is a comparison group: Researchers will compare with the control group to see if the nurse counseling has had an effect.

NCT ID: NCT06018090 Completed - Atrial Fibrillation Clinical Trials

Microembolic Detection in Acute Ischemic Stroke Patients With Atrial Fibrillation and Outcome

Start date: June 6, 2019
Phase:
Study type: Observational [Patient Registry]

This multicenter international prospective cohort study will include patients with AIS with a known or newly diagnosed anticoagulant-naïve AF. All centers will use the same transcranial Doppler machine for one-hour monitoring with bilateral 2-MHz probes within 24 hours of symptom onset. Recordings will be analyzed for MES by a blinded central reader. The primary aim is to determine the proportion of patients with MES and the association of MES with functional outcomes assessed by a modified Rankin scale (mRS) score at 90 days.

NCT ID: NCT05998525 Completed - Clinical trials for Diabetes Mellitus, Type 2

Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography

Start date: June 21, 2021
Phase: Phase 3
Study type: Interventional

Calcification of the coronary arteries is a direct sign of atherosclerotic disease of the coronary arteries and has been shown to be a strong predictor of the risk of cardiovascular diseases, including myocardial infarction and/or cardiac death, especially in patients with Diabetes Mellitus type 2. Therefore, there is great interest in pharmacotherapies that improve the rates of cardiovascular complications, and modify the outcomes of this group of patients. Large randomized controlled trials with SGLT2 inhibitors in patients with DM2 have shown a clear reduction in cardiovascular events among individuals with atherosclerotic disease. Atherosclerosis imaging allows measurable assessments of disease progression and activity, revealing early signs of potential drug effects. Noninvasive methods are preferred for serial imaging in drug trials due to the potential risks associated with invasive procedures. The coronary artery calcium quantification using the Agatston score is the most widely used method

NCT ID: NCT05987462 Completed - Quality of Life Clinical Trials

The Effect of Green Walking on Myocardial Infarction Patients

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The study aimed to experimentally investigate the effect of green walking on body mass index, blood lipids, disease perception, and quality of life in patients with MI.The study aimed to experimentally investigate the effect of green walking on body mass index, blood lipids, disease perception, and quality of life in patients with MI. Research Question 1: What is the impact of green walking on the body mass index (BMI) of patients with MI? Research Question 2: How does green walking influence blood lipid levels (triglycerides, LDL, total cholesterol, and HDL) in patients with MI? Research Question 3: What is the effect of green walking on the perception of the disease in patients with MI? Research Question 4: How does green walking affect the quality of life of patients with MI? 2 Groups: Green walking group and control group

NCT ID: NCT05984134 Completed - Clinical trials for Acute Myocardial Infarction

Efficacy and Safety Study of Thymosin Beta 4 in Patients With Acute Myocardial Infarction

Start date: July 15, 2022
Phase: Phase 2
Study type: Interventional

A multicenter randomized double-blind placebo parallel control design was used in this study. The 90 participants were randomly assigned to placebo, 0.5μg/kg dose group, and 1.0μg/kg dose group in a ratio of 1:1:1. After randomization, subjects received the trial drug or placebo intravenously within 12 hours and on days 2 to 7 after PCI. The patients were observed 90 days after PCI.

NCT ID: NCT05974397 Completed - Clinical trials for Acute Myocardial Infarction

Nationwide Trends in Incidence, Healthcare Utilization, and Mortality in Hospitalized Acute Myocardial Infarction Patients in Taiwan

Start date: September 30, 2021
Phase:
Study type: Observational

This was a retrospective study using the Taiwan's National Health Insurance Research Database (NHIRD). The study employed two study designs for different purposes as follows: - A cross-sectional analysis was conducted to explore the annual incidence trends. - A longitudinal cohort study was conducted to assess baseline characteristics, treatment patterns, long-term healthcare utilization, and cause-specific mortality among incident AMI patients. In each part, the study was conducted for AMI, and separately for ST-segment elevation and non-ST- segment elevation myocardial infarction (STEMI and NSTEMI)

NCT ID: NCT05954819 Completed - Clinical trials for Diabetes Mellitus, Type 2

Effect of Patient Education on Healthy Lifestyle Behaviors and Diabetes Self-management in Diabetics

Start date: July 28, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of planned education given to individuals with diabetes mellitus who had myocardial infarction on healthy lifestyle behaviors and diabetes self-management.