Hypertension Clinical Trial
Official title:
Clinical Decision Support Consortium for AHRQ CDS Research
The goal of the Clinical Decision Support (CDS) Consortium research study is to assess,
define, demonstrate, and evaluate best practices for knowledge management (KM) and CDS in
healthcare information technology across multiple ambulatory care settings and electronic
health records (EHR) technology platforms.
There are seven specific research objectives focusing on two practical areas of
implementation for clinical decision support services: a) healthcare maintenance and
preventive care screening, and b) two chronic disease conditions: Coronary Artery Disease
(CAD), and Adult-onset Diabetes Mellitus (AODM). The research objectives are: 1) Knowledge
management lifecycle, 2) Knowledge specification, 3) Knowledge portal and repository, 4) CDS
knowledge content and public web services, 5) CDS Dashboard, 6)Evaluation, and 7)
Dissemination.
Investigators and developers of electronic health records from both academe and industry
have come together to form the Clinical Decision Support (CDS) Consortium. Members of the
CDS Consortium are intimately involved in creating and providing CDS tools and services in
electronic health records used in both academic settings as well as community-based
physician office practices. These investigators share a common interest and goal of
enhancing the wide-spread adoption of CDS tools and services to improve the delivery of
healthcare both domestically and world-wide.
Our approach to the project is iterative and cyclical: we will begin with a survey of the
knowledge management lifecycle and supporting infrastructure (such as knowledge management
systems, terminology services and data standards) at the participating clinical sites. We
will then work together to define best practices for translating knowledge into a
multi-layered array of human readable knowledge artifacts and public web services. At each
point in this process, we will conduct careful evaluation, documenting lessons learned from
each site. The ultimate work products will fall into three main categories:
First, tangible, actionable knowledge artifacts such as the shareable, human-readable and
computable forms of clinical practice guidelines (CPGs) under study, public web-services for
CDS demonstrations, and a CDS Knowledge Portal and Repository to facilitate widespread
adoption of these artifacts.
Second, detailed guidance and recommendations, based on what we learn from our combined
efforts, for external parties such as the Certification Commission for Health Information
Technology (CCHIT), the Health Information Technology Standards Panel (HITSP), and the
clinical practice guideline developer community.
Third, a set of knowledge and best practices, such as methods for the knowledge management
lifecycle, development of both human readable knowledge artifacts and machine-interpretable
knowledge, and management of decision-support related organizational change. We will share
this knowledge through a variety of channels, such as presentations and academic papers.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Health Services Research
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT04591808 -
Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
|
Phase 3 | |
| Recruiting |
NCT04515303 -
Digital Intervention Participation in DASH
|
||
| Completed |
NCT05433233 -
Effects of Lifestyle Walking on Blood Pressure in Older Adults With Hypertension
|
N/A | |
| Completed |
NCT05491642 -
A Study in Male and Female Participants (After Menopause) With Mild to Moderate High Blood Pressure to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body and How it Moves Into, Through and Out of the Body After Taking Single and Multiple Doses
|
Phase 1 | |
| Completed |
NCT03093532 -
A Hypertension Emergency Department Intervention Aimed at Decreasing Disparities
|
N/A | |
| Completed |
NCT04507867 -
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
|
N/A | |
| Completed |
NCT05529147 -
The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
|
||
| Recruiting |
NCT06363097 -
Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
|
||
| Recruiting |
NCT05976230 -
Special Drug Use Surveillance of Entresto Tablets (Hypertension)
|
||
| Completed |
NCT06008015 -
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fed Conditions in Healthy Volunteers
|
Phase 1 | |
| Completed |
NCT05387174 -
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
|
N/A | |
| Completed |
NCT04082585 -
Total Health Improvement Program Research Project
|
||
| Recruiting |
NCT05121337 -
Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension
|
N/A | |
| Withdrawn |
NCT04922424 -
Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy in Trans Men
|
Phase 1 | |
| Active, not recruiting |
NCT05062161 -
Sleep Duration and Blood Pressure During Sleep
|
N/A | |
| Completed |
NCT05087290 -
LOnger-term Effects of COVID-19 INfection on Blood Vessels And Blood pRessure (LOCHINVAR)
|
||
| Not yet recruiting |
NCT05038774 -
Educational Intervention for Hypertension Management
|
N/A | |
| Completed |
NCT05621694 -
Exploring Oxytocin Response to Meditative Movement
|
N/A | |
| Completed |
NCT05688917 -
Green Coffee Effect on Metabolic Syndrome
|
N/A | |
| Recruiting |
NCT05575453 -
OPTIMA-BP: Empowering PaTients in MAnaging Blood Pressure
|
N/A |