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High Cholesterol clinical trials

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NCT ID: NCT06227819 Completed - Heart Failure Clinical Trials

BVA-200 vs BVA-100 Validation Study

Start date: May 23, 2023
Phase:
Study type: Observational

The proposed study is a prospective, observational, investigator and patient blinded study comparing the results of blood volume measurement using the FDA-cleared Daxor BVA-100 device to the Daxor BVA-200 device. Data from this study may be pooled with data from studies with similar design conducted at other sites, for the purposes of an FDA medical device submission.

NCT ID: NCT05421078 Completed - Clinical trials for Hypercholesterolemia

A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.

Start date: June 27, 2022
Phase: Phase 2
Study type: Interventional

This study will be a placebo-controlled, double-blind, randomized, phase 2 dose-finding study in Japanese patients to evaluate the efficacy, safety, and tolerability of obicetrapib as an adjunct to stable statin therapy.

NCT ID: NCT05266586 Completed - Clinical trials for Hypercholesterolemia

Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy

ROSE2
Start date: March 9, 2022
Phase: Phase 2
Study type: Interventional

This study will be a placebo-controlled, double-blind, randomized, phase 2 study to evaluate the efficacy, safety, and tolerability of obicetrapib 10 mg, both in combination with ezetimibe 10 mg and as monotherapy, as an adjunct to high-intensity statin therapy.

NCT ID: NCT04964544 Completed - High Cholesterol Clinical Trials

Technology-Assisted Cholesterol Trial in Consumers (TACTiC)

TACTiC
Start date: July 8, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this AUS is to evaluate the extent to which participants can safely and effectively self-select, purchase, and use Crestor OTC 5 mg for a 6-month period according to the label.

NCT ID: NCT04787978 Completed - Hypertension Clinical Trials

Creating Healthier Communities Through Meaningful Partnerships: A Model From the National African American Male Wellness Initiative - OSU Partnership

Start date: February 29, 2020
Phase: N/A
Study type: Interventional

Primary Objective: Test feasibility and acceptability of a 24-week community-based lifestyle intervention to improve cardiovascular health among African American males. Secondary Objectives: 1) Navigate participants to establish primary care and address social and patient activation needs that present barriers to wellness; 2) Examine changes in cardiovascular health as per American Heart Association Life's Simple 7 Metrics including blood pressure, cholesterol, glucose, smoking, body mass index, physical activity and dietary intake (1); and 3) Increase African American male participation in clinical trials.

NCT ID: NCT04770389 Completed - Clinical trials for Hypercholesterolemia

Randomized Study of Obicetrapib in Combination With Ezetimibe

OCEAN
Start date: February 23, 2021
Phase: Phase 2
Study type: Interventional

This study will be a placebo-controlled, double-blind, randomized, phase 2 study in participants with mild dyslipidemia to evaluate the efficacy, safety, and tolerability of obicetrapib and ezetimibe combination therapy.

NCT ID: NCT04753606 Completed - Clinical trials for Hypercholesterolemia

Randomized Study of Obicetrapib as an Adjunct to Statin Therapy

ROSE
Start date: February 18, 2021
Phase: Phase 2
Study type: Interventional

This study will be a placebo-controlled, double-blind, randomized, phase 2 dose-finding study to evaluate the efficacy, safety, and tolerability of obicetrapib as an adjunct to high-intensity statin therapy.

NCT ID: NCT04317690 Completed - Breast Cancer Clinical Trials

Online Trial Examining Validity and Reliability of the Shared Decision Making Process Survey

Start date: March 17, 2020
Phase:
Study type: Observational

The purpose of this study is to survey a sample of adults who have recently made a decision about treatment of high cholesterol or high blood pressure or a decision about screening for colorectal cancer, breast cancer, or prostate cancer. The main goal is to gather evidence of the validity and reliability of the Shared Decision Making Process scale. Secondary goal is to gather evidence on the quality of decisions for these common medical situations.

NCT ID: NCT04317274 Completed - Colorectal Cancer Clinical Trials

Online Trial Examining Validity of the Shared Decision Making Process Survey With Video Vignettes

Start date: March 13, 2020
Phase: N/A
Study type: Interventional

This study will recruit subjects online and randomly assigned them to one of four arms. The arms vary by clinical decision (colorectal cancer screening or treatment of high cholesterol) by video order (poor shared decision making followed by good or good shared decision making followed by poor). Participants will view two videos and complete the Shared Decision Making process survey along with a few other measures after each video. Our main hypothesis is that respondents watching the good shared decision making videos will score higher on the Shared Decision Making Process survey compared to those watching the poor videos.

NCT ID: NCT03542240 Completed - Obesity Clinical Trials

Effects of Curcumin Supplementation on Gut Barrier Function in Patients With Metabolic Syndrome

Start date: September 19, 2018
Phase: N/A
Study type: Interventional

This study will investigate the effects of curcumin on the structure/function of the body by investigating whether targeted improvement of intestinal barrier function by supplementation with oral curcumin will result in attenuation of lipopolysaccharide (LPS) translocation and/or intestinal inflammation.