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Fractures, Bone clinical trials

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NCT ID: NCT03880188 Enrolling by invitation - Wounds and Injuries Clinical Trials

Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

FTFDT2
Start date: September 10, 2022
Phase:
Study type: Observational

This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts work to repair wounds long term. Patients who have undergone free autologous dermal fat grafting to treat complex craniofacial wounds 2-30 years ago will have photographs and small biopsies taken of the area that was grafted.

NCT ID: NCT03814928 Enrolling by invitation - Hip Fractures Clinical Trials

Caregivers' eCourse for Recovery After Hip Fracture

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

This project will test feasibility to deliver an online education and skill development program for family/caregivers of older adults recovering from a surgically repaired low-trauma hip fracture. We will also recruit health providers to review and provide feedback on the eCourse before we test its feasibility and acceptability with caregivers.

NCT ID: NCT03788200 Enrolling by invitation - Odontoid Fracture Clinical Trials

Randomized, Controlled Trial of Posterior C1-2 Fusion Versus Bracing Alone for Treatment of Type II Odontoid Process Fractures in the Elderly

Start date: June 14, 2018
Phase: N/A
Study type: Interventional

This prospective study addresses one of the most controversial topics in the treatment of cervical spine trauma: the management of type II odontoid process fractures in the elderly. It is the hypothesis that surgical treatment will result in improved functional outcome measures, neck pain and mortality rates as compared with nonsurgical management. Furthermore, it is hypothesized that surgical treatment of odontoid process fractures will limit hospital re-admissions and development of medical complications secondary to prolonged immobilization in a cervical orthosis and delayed surgery related to late fracture displacement, which are often associated with non-operative care. Additionally, data from this study will be useful in identifying patient-specific predictors of improved outcome which can be used to optimize treatment algorithms and more effectively counsel patients who sustain these injuries.

NCT ID: NCT03462901 Enrolling by invitation - Clavicular Fracture Clinical Trials

Fixation of Displaced Midshaft Clavicular Fractures in Adults by Intramedullary Elastic Rod

Start date: October 30, 2016
Phase: N/A
Study type: Interventional

Clavicular fracture, constitutes 2.6% e 5% of all adult fractures, most are located in the midshaft clavicle with different degrees of displacement. Conservative methods are commonly used for midshaft clavicular fractures treatment, but with various unsatisfactory complications such as nonunion, malunion and shoulders asymmetry. The rate of malunion after conservative treatment for the midshaft clavicular fractures reached 15%, and 30% patients were unsatisfied. Recently, early midshaft clavicular fractures could greatly reduce the incidence rate of nonunion and malunion. Open reduction and plate-screw fixation was considered as the gold standard with the advantages of firm fixation and earlier postoperative mobilization, but also with disadvantages of larger incision and more organizations being exposed, presenting with many postoperative complications. Intramedullary fixation treatment for mid-clavicular fractures has been favored due to its strengths including small incision, less periosteal striping, dispersion of stress and simple to operate However, early intra-medullary implants, such as Hagie pins and Kirschner wires, have been gradually replaced due to insufficient stability. In addition, various nails such as elastic stable intramedullar

NCT ID: NCT03382483 Enrolling by invitation - Clinical trials for Mitigation of Fracture Non-union in Patients at Risk

Observational, Non-interventional Use of LIPUS to Mitigate Fracture Non-union in Patients at Risk

BONES
Start date: October 16, 2017
Phase:
Study type: Observational

This study is one of three separate studies of the Bioventus Observational Non-interventional EXOGEN Studies (BONES) program. Eligibility for each study is determined by fractured bone.

NCT ID: NCT03178799 Enrolling by invitation - Clinical trials for Osteoporosis Fracture

Randomized Fracture Liaison Services

Start date: June 23, 2017
Phase:
Study type: Observational

Aims: To compare clinical outcomes for patients under FLS and usual care at the NTUH MH and BB. Method: Four hundred subjects with new hip fracture or newly identified vertebral fracture are randomly assigned into FLS and usual care (UC). FLS subjects received osteoporosis-related assessments, treatments, consultations on diet, medications, exercise, fall preventions given mainly by care managers with followed up telephone call at 4, 8, 12, 18, 24 months then annually for up to 10 years. Care managers will perform baseline assessments and follow them by telephone annually for up to 10 years for UC subjects. Major outcomes include bone mineral density assessment rate, calcium, vitamin D, and osteoporosis medication initiation and adherence rate, fall and fracture incidences, mortality, and healthcare resource utilizations.

NCT ID: NCT02718170 Enrolling by invitation - Metacarpal Fracture Clinical Trials

Buried Intramedullary K-wire Fixation Compared With Plate and Screw Fixation for Metacarpal Fractures in Unstable Extra-Articular Metacarpal Fractures

Start date: March 2015
Phase: N/A
Study type: Interventional

Randomized controlled trial comparing a technique for buried intramedullary k-wire fixation to plate and screw fixation for unstable extra-articular metacarpal fractures.

NCT ID: NCT02699736 Enrolling by invitation - Clinical trials for Cardiovascular Diseases

EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV

EuroSIDA
Start date: January 1994
Phase:
Study type: Observational [Patient Registry]

The EuroSIDA study is a prospective observational cohort study of 23,000+ patients followed in 100+ clinics in 35 European countries, Israel and Argentina. The study is the largest pan-European cohort study and few studies of a comparable design are available on a global scale. The EuroSIDA study is an ongoing collaboration and patients have been enrolled into the study through 11 cohorts since 1994. The main objective of the study remains the same as in 1994: to prospectively study, clinical, therapeutic, demographic, virological and laboratory data from HIV-1 positive persons across Europe in order to determine their long-term virological, immunological and clinical outcomes. Historically, EuroSIDA has been crucial in reporting key changes in the HIV epidemic, such as the dramatic changes in morbidity and mortality when combination anti-retroviral therapy (cART) was first introduced. As new anti-HCV treatment is introduced to HIV/HCV co-infected patients, it is important for EuroSIDA to remain in the forefront of investigating the treatment benefits and adverse effects. All study documents, study status, newsletters, scientific publications and presentations are available online and are updated continuously at project website. In general terms, the objective of the EuroSIDA study is to continue a long-term, prospective collection of clinical, laboratory and therapeutic data as well as plasma on a large cohort of consecutive HIV infected patients from across Europe in order to (1) assess the factors associated with the clinical, immunological and virological course of HIV infection and HIV-related co-infections and co-morbidities, and (2) continue to provide and develop a surveillance system to describe temporal changes and regional differences in the clinical course of HIV and HIV-related co-infections and co-morbidities in Europe.

NCT ID: NCT02308423 Enrolling by invitation - Clinical trials for Subchondral Fractures of the Glenoid

Clinical and Radiologic Follow up of Subchondral Fractures of the Glenoid

Start date: January 2015
Phase: N/A
Study type: Observational

in this study the investigators will call patients who had Subchondral fractures and treated in our department over the last 20 years. The investigators will evaluate their shoulder function by a questionary, Constant score and radiologic evaluation.