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Fertility Issues clinical trials

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NCT ID: NCT06394752 Recruiting - Fertility Issues Clinical Trials

UTERINE EVALUATION FOR THE IDENTIFICATION OF PATHOLOGY. This Study Will Compare the Intrauterine Pathology Detection Rate Between Standard of Care Hydrosonography, and a New Visual Saline Infusion Device Providing Direct Visualization of the Uterus.

Start date: April 25, 2024
Phase: N/A
Study type: Interventional

This is a prospective, single center, multiple arm cohort study intended to compare the diagnostic accuracy of a Visual Saline Infusion Device (VSI) device, vs standard of care Hydrosonography in reproductive aged women to identify pathology in the uterus.

NCT ID: NCT06387498 Recruiting - Fertility Issues Clinical Trials

Testicular Tissue Cryopreservation (TTC)

TTC
Start date: September 28, 2020
Phase: N/A
Study type: Interventional

The "Testicular Tissue Cryopreservation" study is open to a subset of patients facing disease or treatment regimens that could lead to infertility (gonadotoxic therapies). For some of these patients, experimental testicular tissue cryopreservation is the only fertility preservation option available. The overall objective of this study is to determine the feasibility and acceptability of testicular tissue cryopreservation in male patients of all ages who have a condition or will undergo a treatment that can cause infertility.

NCT ID: NCT06360471 Recruiting - Cancer Clinical Trials

Fertility Preservation and Pregnancy and Offspring Health Outcomes in Female Cancer

Start date: October 1, 2023
Phase:
Study type: Observational [Patient Registry]

To explore whether there is a significant difference in the cumulative live birth rate and maternal and child health outcomes between cancer patients who undergo or do not undergo fertility preservation before receiving anti-tumor treatment and non-cancer patients who undergo assisted reproductive technology treatment/natural pregnancy. This study will be conducted in the Clinical Center of Reproductive Medicine, First Affiliated Hospital of Nanjing Medical University. 2800 women diagnosed with malignant cancers who has desire to reproduce will be enrolled in this study. Statistical analysis of the data will be performed.

NCT ID: NCT06297070 Recruiting - Fertility Issues Clinical Trials

Lifestyle Care for Fertility Outcome Evaluation

PROWESS
Start date: January 24, 2024
Phase:
Study type: Observational

An observational outcome evaluation of the Lifestyle Care for Fertility program.

NCT ID: NCT06194539 Recruiting - Fertility Issues Clinical Trials

Assessing the Fertility Status of Men With Spinal Muscular Atrophy (SMA)

Start date: February 2024
Phase:
Study type: Observational

This study will aim to assess the fertility status of men with Spinal Muscular Atrophy (SMA) not on disease-modifying therapies. Participants will: 1. Complete online questionnaires that will assess SMA diagnosis and disease burden, medical and surgical history, medication usage, and fertility status and perspectives. 2. Over the 3-month initial study baseline period participants will provide two separate ejaculates for semen analysis and a single determination of sperm quality using DNA fragmentation testing using home collection and subsequent shipment to a central laboratory. 3. Over the initial study baseline period of 3 months study participants will obtain a blood test to determine male reproductive hormone levels. During the 24-month study duration, participants will be requested to undergo a yearly semen analysis and complete online relevant questionnaires.

NCT ID: NCT06163079 Recruiting - Fertility Issues Clinical Trials

Assisted Reproductive Techniques (ART) With Sperm Donation : an Inclusive Model of ART for All Women

PMAPT
Start date: March 1, 2023
Phase:
Study type: Observational

This is a monocentric, retrospective, non-interventional study. The main objective is to describe the populations requesting assisted reproductive techniques (ART) with sperm donation ; and compare them between groups depending on their parental project.. The secondary objectives are to describe the center support process in the context of ART with sperm donation, to determine the initial/final orientation of support and the time to care The statistical analysis will be carried out to compare these parameters between groups depending on their parental project The study is taking place in the reproductive medicine department of the regional university hospital centre in Nancy.

NCT ID: NCT06127875 Recruiting - Clinical trials for Stress, Psychological

Effects of Trying to Conceive Using an Home- or Hospital-based Ovulation Monitoring on Stress

Start date: November 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to compare the difference of stress level and anxiety and depression between couples under home ovulation monitoring and hospital ultrasound monitoring.And whether it has a negative effect on the couple's sexual behavior.The participants were all healthy couples with fertility requirements from the reproductive Center of the First Hospital of Jilin University.The main questions it aims to answer are: - [question1] : Does ultrasound monitoring of ovulation increase stress levels and anxiety and depression in couples trying to conceive? - [question2] : Does ovulation monitoring affect couples' sexual function and satisfaction? Participants will be asked to fill out questionnaires three times over four menstrual cycles.

NCT ID: NCT06043609 Recruiting - Cancer Clinical Trials

Outcome Evaluation After Fertility Preservation

Start date: September 21, 2023
Phase:
Study type: Observational

It is important to evaluate outcomes after different fertility preservation strategies. Therefore, this study aims to assess the outcomes after different fertility preservation strategies and identify any factors that may affect their reproductive outcome.

NCT ID: NCT06021886 Recruiting - Fertility Issues Clinical Trials

CS Scar Impact on ART Outcomes

Start date: June 15, 2023
Phase:
Study type: Observational

CS scar impact on ART outcomes, Retrospective Cohort Study IVF outcome can be affected by the presence of caesarean section scar with or without defect in different ways

NCT ID: NCT05980091 Recruiting - Infertility Clinical Trials

Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration.

Start date: September 22, 2023
Phase: Phase 1
Study type: Interventional

The goal of this study is to compare the difference in clinical pregnancy, miscarriage and livebirth rate between day 6 euploid blastocyst transfer on the 6th and the 7th day of progesterone exposure in Hormonal Replacement Therapy (HRT) FET cycles. This prospective & randomized study will only include euploid day 6 blastocysts. This will be the first prospective study of euploid day 6 blastocysts thereby excluding aneuploidy as a cause of miscarriage and implantation failure. The point of randomization will occur on the day of progesterone commencement.