Clinical Trials Logo

Clinical Trial Summary

This study will aim to assess the fertility status of men with Spinal Muscular Atrophy (SMA) not on disease-modifying therapies. Participants will: 1. Complete online questionnaires that will assess SMA diagnosis and disease burden, medical and surgical history, medication usage, and fertility status and perspectives. 2. Over the 3-month initial study baseline period participants will provide two separate ejaculates for semen analysis and a single determination of sperm quality using DNA fragmentation testing using home collection and subsequent shipment to a central laboratory. 3. Over the initial study baseline period of 3 months study participants will obtain a blood test to determine male reproductive hormone levels. During the 24-month study duration, participants will be requested to undergo a yearly semen analysis and complete online relevant questionnaires.


Clinical Trial Description

Study participants will: 1. Complete online questionnaires that will assess SMA diagnosis and disease burden, medical and surgical history, medication usage, and fertility status and perspectives. 2. Over the 3-month initial study baseline period participants will provide two separate ejaculates for semen analysis and a single determination of sperm quality using DNA fragmentation testing using home collection and subsequent shipment to a central laboratory. 3. Over the initial study baseline period of 3 months study participants will obtain a blood test to determine male reproductive hormone levels. During the 24-month study duration, participants will be requested to undergo a yearly semen analysis and complete online relevant questionnaires. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06194539
Study type Observational
Source Bar-Chama, Natan, M.D.
Contact Natan Bar-Chama, MD
Phone 2016941781
Email support@malefertilitysma.com
Status Recruiting
Phase
Start date February 2024
Completion date July 2026

See also
  Status Clinical Trial Phase
Recruiting NCT06387498 - Testicular Tissue Cryopreservation (TTC) N/A
Recruiting NCT04519593 - ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma N/A
Recruiting NCT05980091 - Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration. Phase 1
Recruiting NCT06043609 - Outcome Evaluation After Fertility Preservation
Not yet recruiting NCT05048771 - Fertility and Temporality in Pediatric Oncology
Completed NCT05368194 - Food Intake and Epigenetic Alteration in the Spermatozoa of Singletons and Twins N/A
Recruiting NCT05176535 - Determination of Vaginal Colonization and the Effect of an Oral Probiotic (PROSALVAG) N/A
Recruiting NCT06360471 - Fertility Preservation and Pregnancy and Offspring Health Outcomes in Female Cancer
Recruiting NCT05271981 - Fertility After Uterine Artery Embolization
Recruiting NCT05815719 - Continuous Double Ovarian Stimulation. Phase 4
Recruiting NCT06127875 - Effects of Trying to Conceive Using an Home- or Hospital-based Ovulation Monitoring on Stress
Recruiting NCT05658848 - Effect of Collaborative Infertility Counseling on Coping Strategies and Marital Satisfaction N/A
Not yet recruiting NCT05385848 - Autologous Platelet-rich Plasma (PRP) Infusion to Improve Outcomes in Women With Ovarian Insufficiency: a Pilot Study N/A
Completed NCT04396210 - Patients Perspectives on Discontinuation of Their Fertility Treatment Due to the COVID-19 Pandemic
Completed NCT05134090 - Percutaneous Laparoscopy for Ovarian Tissue Cryopreservation.
Completed NCT05905289 - Survival and Reproductive Outcomes of Malignant Ovarian Germ Cell Tumors
Recruiting NCT05316467 - Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma Phase 2/Phase 3
Completed NCT04600869 - Effects of Naturalistic Decision-Making Model-based Oncofertility Care Education N/A
Withdrawn NCT04683237 - Liraglutide Plus Megestrol Acetate in Endometrial Atypical Hyperplasia Phase 2/Phase 3
Not yet recruiting NCT06179420 - The Effectiveness of Advanced Decision Support Tool (OPT-IVF) for IVF Treatment