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Fatigue clinical trials

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NCT ID: NCT05528250 Recruiting - Muscle Fatigue Clinical Trials

The Effect of Quadriceps Muscle Fatigue on Balance

Start date: October 25, 2022
Phase:
Study type: Observational

This study; will be conducted to investigate the effect of quadriceps muscle fatigue on static and dynamic balance in regular physical activity individuals and sedentary individuals. International Physical Activity Questionnaire Short Form (IPAQ), Mini BESTest, Modified Borg Scale questionnaire and acute muscle fatigue protocol will be applied and Y balance Test, Flamingo Balance Test, Tecnobody Balance Measurement, EMG measurement, anthropometric measurements and digital dynamometer measurements will be made.

NCT ID: NCT05525403 Completed - Healthy Clinical Trials

The Effects of Fatigue on Exercise-Induced Hypoalgesia During a Dynamic Resistance Exercise

Start date: October 28, 2022
Phase: N/A
Study type: Interventional

The primary purpose of this study is to compare immediate changes in pain sensitivity (pressure pain threshold) during quiet rest, low fatigue exercise, and high fatigue exercise.

NCT ID: NCT05524688 Terminated - Clinical trials for Autologous Haemopoietic Stem Cell Transplant

Beta-glucan and Fatigue in HSCT Survivors

Start date: February 10, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is a single-center, randomized, double-blind, placebo-controlled study exploring the effects of a yeast-derived β-glucan on clinically significant fatigue among survivors of autologous HCT due to multiple myeloma. The primary aim is to evaluate the effect of β-glucan supplementation on changes in fatigue symptoms, as assessed by the Brief Fatigue Inventory (BFI) global fatigue score, by testing the differences in changes in scores from baseline to the mid-point (mean of weeks 1-4) and to the end of the intervention (mean of weeks 5-8).

NCT ID: NCT05524441 Recruiting - Fatigue Clinical Trials

Fatigue in Short-Haul Operations

FISH-Ops
Start date: August 31, 2022
Phase:
Study type: Observational

The purpose of the present study is to assess fatigue levels of short-haul pilots during normal operations. The investigators will collect objective and subjective sleep, sleepiness, workload, and performance data from on-duty pilots during short-haul flight operations. Data will be collected during days off prior to the trip start, during flights, and during days off following the flight operations.

NCT ID: NCT05518773 Recruiting - Clinical trials for Spinal Muscular Atrophy

Mechanisms and Treatment of Exercise Intolerance and Persistent Fatigue in Spinal Muscular Atrophy

Start date: December 15, 2022
Phase:
Study type: Observational

This study will focus on the pathophysiological underpinnings of reduced exercise capacity and fatigue in ambulatory patients with spinal muscular atrophy (SMA). There has been laboratory evidence to suggest that the molecular mechanisms underlying mitochondrial biogenesis may be vulnerable to survival motor neuron (SMN) protein deficiency. This is an observational, single visit study including 34 ambulatory SMA patients treated with SMN repletion therapies (risdiplam or nusinersen) for at least 6 months at enrollment.

NCT ID: NCT05515003 Recruiting - Clinical trials for Inflammatory Bowel Diseases

The Effect of Patient Education on Fatigue in Inflammatory Bowel Disease

IBD
Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Introduction: Fatigue is a serious symptom that is seen in a significant portion of IBD patients and negatively affects the patient's quality of life. The aim of this study is to evaluate the effect of patient education on the management of fatigue, which is common in inflammatory bowel diseases. Material and methods: This study will be planned with nonrandomized control group, pretest-posttest design. It is planned that the sample group will consist of at least 84 patients, 42 of which are in the intervention group and 42 in the control group. The patients in the intervention group will be evaluated in terms of fatigue and factors that may affect it, and an individualized education program will be offered according to the needs of the patient.For the patients in the control group, only the scales used in data collection will be filled, and no education will be planned. One month after the first interviews, both groups will fill in the scales again.

NCT ID: NCT05490966 Completed - Muscle Tightness Clinical Trials

Effects of Isometric Muscle Fatigue on Trunk Muscle Stiffness

Start date: September 10, 2022
Phase: N/A
Study type: Interventional

Interventional study of the effects of a trunk extensor muscles fatigue protocol on trunk extensors stiffness.

NCT ID: NCT05489003 Recruiting - Clinical trials for Chronic Pancreatitis

Fatigue, Psychological Comorbidity and Quality of Life Among Patients With Chronic Pancreatitis in China.

Start date: August 1, 2022
Phase:
Study type: Observational

This study will investigate the status of fatigue, psychological comorbidity and quality of life among patients with chronic pancreatitis in China and analyze their influencing factors.

NCT ID: NCT05487131 Recruiting - Fatigue Clinical Trials

Neuromodulation and Fatigue

Start date: June 3, 2023
Phase: N/A
Study type: Interventional

In this project, we aim to determine any potential effects of a weak electrical current applied to the neck or thoracic area on functional capacity and muscle activation. Healthy individuals will participate in one familiarization followed by three experimental sessions. Fatigability and motor function will be assessed in each test session.

NCT ID: NCT05484661 Completed - Aging Clinical Trials

Mechanisms to Reduce Mental and Physical Fatigue Following Exercise Training in Older Adults

BCAA
Start date: December 22, 2022
Phase: N/A
Study type: Interventional

Fatigue is a strong predictor of negative health outcomes in older adults. The research in this study will compared the effects of 8-weeks of branched chain amino acids (BCAAs: dietary supplements commonly taken to improve muscle growth and exercise performance) added to exercise on fatigue compared to exercise with a placebo (an inactive, harmless substance). BCAAs could have an impact on improving fatigue common in older adults, especially when exercising.