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Fatigue clinical trials

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NCT ID: NCT05671588 Recruiting - Multiple Sclerosis Clinical Trials

Cardiovascular Fitness of Patients With Multiple Sclerosis, Effect of Exercise on Fatigue and Depression

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

This study is focused on patients with multiple sclerosis (MS), their cardiovascular fitness, and the effect of combined controlled training on the perception of fatigue, the development of depression, and quality of life in the first year after diagnosis.

NCT ID: NCT05668247 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

The Effects on Sleep qualıty and fatıgue Level of Foot Bath

Start date: May 5, 2017
Phase: N/A
Study type: Interventional

Aims and objectives: To determine the effect of foot bath on sleep quality and fatigue level in patients with chronic obstructive pulmonary disease (COPD). Background: İnsomnia and fatigue are one of the most common symptoms in people with COPD and adversely affects their activities of daily living. Design: This study was conducted as a nonrandomized controlled trial. Methods:The study sample comprised 70 patients who met the inclusion criteria.Data were collected with Patient Information Form, Pittsburgh Sleep Quality Index and Piper Fatigue Scale. Intervention group; The 30-day foot bath was administered for 10 minutes before bedtime, while no control was performed in the control group. The Pittsburgh Sleep Quality Index (PUKI) and the Piper Fatigue Scale were administered in both groups at the beginning of the service (first follow-up) and four weeks later (second follow-up) at the outpatient clinic. Conclusions: The foot bath by individuals with COPD was determined to significantly improve the participants'levels sleep quality and fatigue.

NCT ID: NCT05667077 Not yet recruiting - Clinical trials for Post-COVID-19 Syndrome

The Effect of Amantadine on Post-COVD-19 Fatigue

Start date: December 26, 2022
Phase: Phase 2
Study type: Interventional

This study aimed to investigate amantadine's safety and its effect on reducing post-COVID-19 fatigue.

NCT ID: NCT05664711 Active, not recruiting - Clinical trials for Chronic Fatigue Syndrome

Effect of Stellate Ganglion Block on ME/CFS

SGB_ME
Start date: March 15, 2023
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to study the effects of stellate ganglion block (SGB) in participants with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The main questions it aims to answer are: Does SGB treatment improve symptoms of ME/CFS (e.g. brain fog, fatigue)? Do changes in symptoms go along with changes in blood or saliva? Participants will receive a total of six blocks over three weeks (one block on each side, one day apart, per week). Prior to treatment and at two points following treatment, participants will complete surveys, take a cognitive (puzzle type) test, and provide blood and saliva for analysis. Participants will measure their heart rate daily using a free smart phone app.

NCT ID: NCT05664009 Recruiting - Fatigue Clinical Trials

The Safety and Efficacy of Redsenol-1 Plus on Cancer-related Fatigue in Adults

Start date: May 30, 2023
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the safety and efficacy of Redsenol-1 Plus on cancer-related fatigue (CRF) in adults. The change in the severity of CRF from baseline at week 12 will be assessed by the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) fatigue subscale, and compared between Redsenol-1 Plus and placebo groups. Additionally, the safety and tolerability of Redsenol-1 Plus, as compared to placebo, will be measured by the occurrence of and/or changes in treatment-emergent adverse events (AEs).

NCT ID: NCT05657197 Recruiting - Clinical trials for Inflammatory Bowel Diseases

The Effect of Intensive Physical Exercise on Fatigue and Quality of Life in Patients With Quiescent Inflammatory Bowel Disease

ENERGIZE-IBD
Start date: January 10, 2023
Phase: N/A
Study type: Interventional

In patients with inflammatory bowel diseases (IBD), characterized by relapsing intestinal inflammation, chronic fatigue is a burdensome and highly prevalent symptom. The aetiology is thought to be multifactorial, including complex interactions of psychological and physical factors such as immunological profiles and gut microbiota. Unfortunately, specific treatment strategies are currently lacking. Since fatigued patients have an impaired physical fitness and are less physically active than patients without fatigue, it is hypothesised that physical exercise might be an effective complementary treatment for patients with IBD suffering from fatigue. During a previous pilot cohort study, significant improvements in fatigue complaints and quality of life were observed following a personalised and intensive exercise program. In this study, a multicenter randomized controlled trial will be performed to further investigate this assumed beneficial effect of intensive physical exercise.

NCT ID: NCT05651438 Recruiting - E-Athletes Clinical Trials

Pain, Fatigue and Sleep Quality of E-Athletes

Start date: January 1, 2023
Phase:
Study type: Observational

E-Sports, which attract great attention in the media and social networks, brings health problems and some risks, depending on the attractiveness of games and the time spent in the digital world. When the investigators examine the literature, although different studies are showing that E-Athletes experience pain and sleep problems, no study examines the factors related to pain and sleep quality together. Therefore, our study was planned to examine the factors associated with pain, fatigue, and sleep quality in E-Athletes.

NCT ID: NCT05636696 Active, not recruiting - Neoplasms Clinical Trials

COMPANION: A Couple Intervention Targeting Cancer-related Fatigue

COMPANION
Start date: September 21, 2022
Phase: N/A
Study type: Interventional

Chronic cancer-related fatigue (CCRF) is a disturbing condition that persists in up to 25% of cancer patients after completion of treatment. While mindfulness-based interventions are effective in relieving CCRF, these typically target the patient alone. Growing evidence suggests that including partners and targeting the dyadic context can increase and broaden the interventions' efficacy. The proposed study is a pilot trial testing the acceptability and potential efficacy of a mindfulness intervention directed at couples.

NCT ID: NCT05631210 Completed - Clinical trials for Information Fatigue Syndrome

Using Pictograms to Make Privacy Agreements More Accessible

Start date: September 6, 2019
Phase: N/A
Study type: Interventional

Background: Privacy agreements can foster trust between users and data collecting entities by reducing the fear of data sharing. Users typically identify concerns with their data privacy settings, especially when it comes to health data, but due to the complexity and length of privacy agreements, users opt to quickly consent and agree to the terms without fully understanding them. Objective: This study explores the use of pictograms as potential elements to assist in improving the transparency and explanation of privacy agreements. Methods: During the development of the pictograms, the Double Diamond design process was applied for 3 instances of user interactions and 3 iterations of pictograms. The testing was done by performing a comparative study between a control group, which received a fictional privacy agreement about a health tracking wearable with no pictograms, and an experimental group, which received pictograms. The pictograms were individually tested to assess their efficacy by using an estimated comprehension of information symbols test.

NCT ID: NCT05631171 Completed - Fatigue Clinical Trials

Feasibility Study of Adhera® Fatigue Digital Program for Patients With Long COVID-related Fatigue

COVIDAI
Start date: December 13, 2022
Phase: N/A
Study type: Interventional

Adhera® Fatigue Digital Program (or AFDP) is a digital health program based on behavioral and emotional change techniques that provides personalized physical and emotional self-management support for patients with long COVID-related fatigue. The digital health solution is designed to be used for 3 months, and includes a mobile application and a smartwatch. This is a clinical study, with 30 participants in the experimental intervention group and 30 in the control group, that will be carried out at the Jordi Gol Primary Care Research Institute (IDIAPJGol) - Institut Català de la Salut and Distrito sanitario Aljarafe-Sevilla Norte (DASN) - Servicio Andaluz de Salud, in Spain. The investigators will focus on evaluating the feasibility of the program in supporting fatigue and also physical and emotional self-management and, consequently, in improving the patients' well-being and quality of life.