Diabetes Mellitus Clinical Trial
Official title:
Comparison in Survival in Patients With Insulin-dependent and Non-insulin-dependent Diabetes Mellitus With Known or Suspected Coronary Artery Disease Undergoing Major Non-cardiac Surgery
Patients with CAD and diabetes mellitus have a better prognosis than patients with CAD and no diabetes mellitus. In acute coronary syndrome patients with an insulin therapy had a better survival than patients with oral antidiabetics. But there is not known wether perioperative therapy with insulin or oral antidiabetics is associated with higher risk for higher perioperative cardiac morbidity and mortality and worse long-term survival.
Diabetes mellitus is an important risk factor for arteriosclerosis in general and for
coronary artery disease. Patients with CAD have a worse prognosis if they have diabetes
mellitus. But it is not known whether the treatment of Dm has an influence on mortality or
morbidity.
In face of the high number of patients with Dm and the therapeutic consequences this
prospective study wants to compare short-time and long-time morbidity in Patients with Dm
undergoing major non-vascular surgery. Inclusion criteria are medically treated Dm (insulin
or oral antidiabetics) and major non cardiac surgery.
The "normal" perioperative treatment of the study is not changed by the study itself.
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Observational Model: Cohort, Time Perspective: Prospective
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