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Determinants of Depression and Its Impact on Quality of Life in Patients With Chronic Pancreatitis

Depression Clinical Trial

Official title:
Determinants of Depression and Its Impact on Quality of Life in Patients With Chronic Pancreatitis

Clinical Trial Summary

Chronic pancreatitis (CP) is associated with recurrent intractable abdominal pain, pancreatic exocrine insufficiency and endocrine dysfunction. Very few studies had evaluated the quality of life in CP, and even a fewer have assessed the mental status in these patients. In the current study, we proposed to evaluate the the relationship between pain, quality of life and depression status in two large independent cohorts of patients with CP. We also proposed to evaluate the brain metabolites in the right and left anterior cingulate cortex, basal ganglia, hippocampus and prefrontal cortex using magnetic resonance spectroscopy. We further proposed to evaluate the pasta metabolites and look for associations with the mental state. Finally, we proposed to evaluate how CP related education of the patients could impact on their mental status and response to interventions on pain.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04867304
Study type Observational
Source Asian Institute of Gastroenterology, India
Contact
Status Completed
Phase
Start date February 1, 2018
Completion date January 31, 2020
View Details
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