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The Efficacy, Safety, and Tolerability of Probiotics on the Mood and Cognition of Depressed Patients

Depression Clinical Trial

Official title:
The Efficacy, Safety, and Tolerability of Probiotics on the Mood and Cognition of Depressed Patients

Clinical Trial Summary

This study will be an 8-week open-label pilot study examining subjective and objective changes in mood, anxiety, cognition, and sleep before and after the introduction of a probiotic supplement containing Lactobacillus helveticus and Bifidobacterium longum in 10 treatment-naïve participants diagnosed with major depressive disorder (MDD). In order to examine the full composition of the micro biome, the investigators will also be collecting and analyzing fecal samples as well as blood samples to examine changes in plasma levels of inflammatory markers, 5-HT, and tryptophan in order to look at possible underlying mechanisms of any changes seen.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02838043
Study type Interventional
Source Queen's University
Contact
Status Completed
Phase Phase 3
Start date August 2016
Completion date May 2018
View Details
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