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Dentin Hypersensitivity clinical trials

View clinical trials related to Dentin Hypersensitivity.

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NCT ID: NCT06276777 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

The Effect of Using Desensitizers Containing S-PRG In Treatment Of Dentin Hypersensitivity Over 6 Months: A Randomized Clinical Trial

S-PRG
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effect of desensitizer containing S-PRG have similar effect as sodium fluoride with functionalized tri-calcium phosphate containing desensitizer in relieving dentinal hypersensitivity in adult patients for six months follow-up. patients will be asked to report pain degree on the visual analogue scale (VAS) along the follow up periods on both groups.

NCT ID: NCT06264453 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

A Study to Evaluate the Efficacy and Safety of KH001 in Patients With Dentin Hypersensitivity

Start date: March 11, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of KH001 in patients with dentin hypersensitivity.

NCT ID: NCT06154941 Recruiting - Clinical trials for Dentin Hypersensitivity

Clinical Evaluation of Giomer Based Varnish Versus CPP-ACP Varnish in the Management of Dentin Hypersensitivity: a Randomized Clinical Trial

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Dentin hypersensitivity is a drastic problem, which threaten many dental patients. According to the last published systematic review and meta analysis at 2019, the prevalence of dentin hypersensitivity is being 33.5% among the population. Moreover, it was determined that young adults with age range from 18 to 44 years exhibited high percentage (43.9%) of such problem

NCT ID: NCT06113874 Completed - Clinical trials for Dentin Hypersensitivity

The Influence of Desensitizing Agent on Postoperative Sensitivity in Posterior Composite Restoration

Start date: July 5, 2022
Phase: N/A
Study type: Interventional

This study aims to investigate the influence of desensitizing agents on reducing post-operative sensitivity in posterior composite.

NCT ID: NCT06025084 Completed - Clinical trials for Dentin Hypersensitivity

The Effect of the Egg Shell Nanoparticles Combined With Titanium Dioxide Nanoparticles

Start date: December 1, 2022
Phase: Phase 1
Study type: Interventional

Dentin hypersensitivity is one of the most commonly occurring clinical dental conditions which is characterized by short and sharp pain which arises from exposed dentin in response to external stimuli, which typically are thermal, evaporative, tactile, osmotic or chemical. Hypersensitive dentin is mostly found in buccal tooth areas, in which enamel is missing because of abrasion, attrition, or erosion. The most generally accepted theory regarding the mechanism of dentin hypersensitivity is the hydrodynamic theory. It proposes that a pain-provoking stimulus increases the flow of the dentinal tubular fluid and consequently, stimulates the nerves around the odontoblasts, leading to dentin hypersensitivity.

NCT ID: NCT05927831 Recruiting - Clinical trials for Dentin Hypersensitivity

Grape Seed Extract VS Low Level Laser Therapy for Dentin Hypersensitivity

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

Dentin hypersensitivity (DH) is a common clinical problem frequently seen in dental patients. According to Splieth et al., the prevalence of dentin hypersensitivity is 3-98% in adult population.DH is described as a short, sharp pain or discomfort that responses to certain stimuli, typically thermal, tactile, osmotic or chemical, due to exposed dentinal surface which can be explained by the hydrodynamic theory. The laser is a narrow, focused beam of light emitted to vaporise, fuse, melt, or seal dentinal tubules using laser heat to induce hydroxyapatite crystals for recrystallisation of the mineral component of dentine. The obliteration of dentinal tubules is caused by heat generated by laser beam which inhibits the transmission of the stimulus in the dentinal tubules. Grape seed extract contains proanthocyanidins (PA) which is able to bind to proline-rich proteins, like collagen, and contributes in enzyme proline hydroxylase activity that is essential for the biosynthesis of collagen in the dentin. The cross-linking action of collagen fibrils in dentin also able to prevent mineral loss.

NCT ID: NCT05768373 Completed - Clinical trials for Dentin Hypersensitivity

A Comparison Study of Hypersensitivity Treatment

Start date: April 4, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effect of 3M™ Clinpro™ Fluoride Aqueous Solution (experimental) on Dentin Hypersensitivity (DHS) in comparison to 3M™ Vanish™ (commercialized, control] in patients who have DHS. Participants will be asked to complete the following activities: Undergo a pre-treatment washout period for 3- to 6-weeks (± 4 days) post-enrollment. During this time, the Subject is to only use the provided oral hygiene products. Hypersensitivity will be assessed prior to (baseline) and immediately after sample application. Subject will be asked to come to the facility for hypersensitivity assessments at 24 hours, 7 days, and 30 days after the treatment visit. Researchers will compare 3M™ Clinpro™ Fluoride Aqueous Solution to 3M™ Vanish™ to evaluate if the effect of Clinpro™ on DHS treatment is non-inferior to Vanish™.

NCT ID: NCT05623761 Completed - Gingivitis Clinical Trials

Toothpastes With Thermal Water for Oral Health

Start date: November 1, 2022
Phase: Phase 4
Study type: Interventional

The aim of the study is to compare the effect of toothpastes containing thermal water of Castera-Verduzan with 1450 ppm fluoride and without fluorinated derivatives on oral hygiene, gingivitis, and dentin hypersensitivity in young adults.

NCT ID: NCT05501691 Completed - Clinical trials for Dentin Hypersensitivity

Effect of Diode Laser on Sensitive NCCLs Prior to Composite Restoration

Start date: October 4, 2022
Phase: N/A
Study type: Interventional

This study will investigate the efficacy of three diode laser wavelengths 445 nm, 660 nm, 970 nm when applied just before placement of composite restoration on reducing postoperative sensitivity from Non-carious cervical lesions (NCCLs) with class V cavity preparation.

NCT ID: NCT05122312 Completed - Clinical trials for Dentin Hypersensitivity

Comparative Study on the Efficacy of OliNano SEAL and Curodont D' Senz in Treatment of Dentin Hypersensitivity

Start date: April 20, 2020
Phase: Phase 4
Study type: Interventional

This study was conducted to evaluate and compare the efficacy of Olinanoseal and Curodont D'Senz in treatment of dentin hypersensitivity.