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Dentin Hypersensitivity clinical trials

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NCT ID: NCT06466200 Not yet recruiting - Quality of Life Clinical Trials

Validation of a French Version of the DHEQ

DHEQ-VALID
Start date: July 2024
Phase: N/A
Study type: Interventional

Dentin hypersensitivity (DH) results in brief, sharp pain in response to a stimulus. It often seems to be underdiagnosed but also undertreated due to the lack of consensus on the topic. DH has been shown to affects patients' quality of life. The Dentine Hypersensitivity Experience Questionnaire (DHEQ)is developed and validated : which is questionnaire assessing specifically the impact of DH on patient's quality of life. The DHEQ aims to help diagnose DH and assess the impact and subjective experience of the patient in order to better meet their expectations in terms of treatment. A French version, the DHEQ-fr, has been proposed (translation-counter-translation process and pilot study); however, it has not yet been validated (psychometric tests, test-retest). The main objective of the present study is to validate DHEQ-fr through a multicenter clinical study (three centers in France) in adult patients. The secondary objective is to compare the results of DHEQ-fr with those of the general oral health assessment index and oral health impact profil for the same patients. Patients are split between three DH groups (Schiff scores 1, 2 and 3) and a control group (non-DH). The overall sample size (all centers considered) for the DH group is 162 subjects divided into 54 subjects for each Schiff score (1 to 3; after cold air stimulation), with a control group of 54 subjects. A re-test will be performed, at 15 days, on a random sample of 60 subjects from the study population (in total: 15 non-DH subjects; 15 with a Schiff score of 1; 15 with a score of 2; 15 with a score of 3). The study of psychometric properties such as acceptability, internal consistency, reproducibility and internal structure validity will allow the validation of this French version of the DHEQ.

NCT ID: NCT06464939 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

Phase 2 Study of KH001 in Long-term Relief From Dentin Hypersensitivity

Start date: August 19, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of KH001 in subjects with dentin hypersensitivity.

NCT ID: NCT06276777 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

The Effect of Using Desensitizers Containing S-PRG In Treatment Of Dentin Hypersensitivity Over 6 Months: A Randomized Clinical Trial

S-PRG
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effect of desensitizer containing S-PRG have similar effect as sodium fluoride with functionalized tri-calcium phosphate containing desensitizer in relieving dentinal hypersensitivity in adult patients for six months follow-up. patients will be asked to report pain degree on the visual analogue scale (VAS) along the follow up periods on both groups.

NCT ID: NCT04731766 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

Effect of Using Different Varnishes on Dentin Hypersensitivity; Na Fluoride and Nano-silver Fluoride

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

2 different varnishes will be used to test their effectiveness in controlling teeth hypersensitivity in adult patient.

NCT ID: NCT04614727 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

Desensitizing Efficacy of Polymeric Nano Calcium Fluoride Containing Varnish

Start date: February 10, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the Desensitizing efficacy of polymeric nano calcium fluoride containing varnish and its implementation into clinical practice.

NCT ID: NCT04484844 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

Clinical Evaluation of Efficacy of Shield Force Plus Varnish VS Sodium Fluoride on Dentin Hypersensitivity

Start date: October 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study to compare the clinical effectiveness of Shield Force Plus (SFP) versus sodium fluoride varnish in the management of hypersensitivity of cervical dentin in adult patients for 8weeks.

NCT ID: NCT03061383 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

Reduction of Dentine Hypersensitivity Using 8% Arginine Based Toothpaste and 8% Strontium Acetate Based Toothpaste (DH)

DH
Start date: March 3, 2017
Phase: N/A
Study type: Interventional

This is a randomized, triple-blind, placebo-controlled study. 51 subjects with a confirmed diagnosis of dentin hypersensitivity were randomized to one of three treatments: Arginine based toothpaste, strontium acetate based toothpaste , or placebo. Treatment will be done at baseline then patients will use the toothpaste at home twice per day by using soft bristled tooth brush and the given dentifrice using modified stillmans method as explained by examiner. Standard test stimuli is calibrated short blast of air syringe, will be applied to sensitive dentin surfaces. Subjects recorded the intensity of sensitivity in response to stimulus on a visual analog scale at baseline, and after 1 week, 2 weeks and 3 months.