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Dentin Hypersensitivity clinical trials

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NCT ID: NCT04896294 Completed - Clinical trials for Dentin Hypersensitivity

Ca-hydroxyapatite, Fluoroapatite, and Mg-Zn-hydroxyapatite for Dentin Hypersensitivity Management

Start date: April 24, 2021
Phase: Phase 4
Study type: Interventional

This will be a double-blind, randomized, three-arm parallel groups study of the effect of toothpastes containing Ca-hydroxyapatite (HAP), Mg-Zn-hydroxyapatite (Zn-Mg-HAP), or fluoroapatite (FAP). The aim of the study is to compare the effect of toothpastes containing Ca-hydroxyapatite (HAP), fluoroapatite (FAP), and Mg-Zn-hydroxyapatite (Mg-Zn-HAP) on dentin hypersensitivity associated with dental abrasion. Materials and methods. Thirty consent patients aged 35-45 with dentin hypersensitivity associated with abrasion will be recruited for the study. The study will have 2 phases: preparatory phase (recruitment of the patients, standardization of their oral hygiene protocols, wash-out period, calibration of the researchers and training) and the main part (double-blind, randomized, parallel groups study of toothpastes effect). Patients will be randomly divided into 3 groups (group 1 - toothpastes with Ca-HAP, group 2 - toothpastes with Zn-Mg-HAP, group 3 - toothpastes with FAP). Clinical examination will be performed at the baseline, after 2 and 4 weeks, and will include patient's interview, oral hygiene level assessment (OHI-S), and dentin sensitivity testing (Shiff's index). The null hypothesis is that there will be no statistically significant differences in dentin sensitivity level between the study groups.

NCT ID: NCT04887181 Completed - Clinical trials for Dentin Hypersensitivity

The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life

Start date: March 4, 2020
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effects of a self etch adhesive resin and two desensitizing agents(Calcium phosphate, 5% glutaraldehyde) in treatment of dentin hypersensitivity on the quality of life of individuals.

NCT ID: NCT04819867 Completed - Clinical trials for Dentin Hypersensitivity

Comparison Of The Effect Of Propolis And Gluma Desensitizer On The Management Of Dentin Hypersensitivity

Start date: December 16, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

Objective The purpose of this study was to compare the effect of Propolis and Gluma desensitizer on the management of Dentin Hypersensitivity Methods Patients with dentin hypersensitivity exhibiting pain scores of at least '2' on the visual analog scale (VAS) were included in the study. Patient's response to an air blast stimulus was noted on Visual Analogue Scale and Schiff's scale in order to record the degree of hypersensitivity of teeth. There were 80 teeth, 40 in each group. The baseline scores were obtained. Propolis and Gluma desensitizer were randomly applied to each hypersensitive tooth. VAS scores and Schiff's sensitivity score for air blast stimulus were then noted at baseline, immediate, after 1 week and then after 1 month of application.

NCT ID: NCT04804423 Completed - Clinical trials for Dentin Hypersensitivity

Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth

Start date: January 13, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

This observational cohort study aims to evaluate the short-term (3 months) efficacy of the standard fluoride therapy in the German National Health System for managing hypersensitive carious lesions in primary teeth (fluoride varnish application), and further compare it to a different fluoride therapy utilizing a silver-containing fluoride agent combined with potassium iodide solution.

NCT ID: NCT04731766 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

Effect of Using Different Varnishes on Dentin Hypersensitivity; Na Fluoride and Nano-silver Fluoride

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

2 different varnishes will be used to test their effectiveness in controlling teeth hypersensitivity in adult patient.

NCT ID: NCT04614727 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

Desensitizing Efficacy of Polymeric Nano Calcium Fluoride Containing Varnish

Start date: February 10, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the Desensitizing efficacy of polymeric nano calcium fluoride containing varnish and its implementation into clinical practice.

NCT ID: NCT04591444 Completed - Dentin Sensitivity Clinical Trials

Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity

Start date: January 2017
Phase: Phase 3
Study type: Interventional

Dentin hypersensitivity (DH) can be defined as acute, short-duration pain from open dentin tubules in exposed dentin. The symptom of DH is subjective and varies from patient to patient and may present as mild discomfort or as a high-intensity pain, which can affect the individual's quality of life, interfering with their eating and hygiene habits. One approach to treatment would be the use of agents that chemically desensitize sensory nerves, blocking the transmission of nerve stimuli to the central nervous system. The effectiveness of desensitizing treatments is influenced by several factors present in the oral cavity, which can contribute to a greater effect of these agents but can also be responsible for removing them from the dental surface. To date, studies have been carried out in the short term, not exceeding an average period of 12 weeks, so there is no consensus on the technique or agent that will guarantee the most effective and lasting effect against DH, not even the ideal period for reapplication. Thus, more studies are needed to assess the clinical behavior of desensitizing products on the market, especially the most recent releases. Therefore, the aim of this study was to clinically compare the effectiveness of different office treatments for DH, being ClinproTM White Varnish, ClinproTM XT Varnish, and a control group (placebo) through pain assessment with the Visual Analog Scale (VAS), after stimulation with air from the triple syringe.

NCT ID: NCT04527159 Completed - Clinical trials for Dentin Hypersensitivity

Comparison of Desensitizing Materials

Start date: January 6, 2019
Phase: N/A
Study type: Interventional

To compare the efficacy of two commercially available in-office desensitizing agents (Fluoraphat Pro and VivaSens®), in the treatment of dentinal hypersensitivity.

NCT ID: NCT04512625 Completed - Clinical trials for Dentin Hypersensitivity

Desensitizers in Reducing Post Tooth Preparation Sensitivity for a Fixed Dental Prosthesis

Start date: November 28, 2019
Phase: N/A
Study type: Interventional

The main purpose of the present study was to evaluate and compare the effectiveness of three kinds of commercially available desensitizing agents: Gluma, Sheildforce plus, and Telio CS desensitizers in reducing the pre- and post-cementation sensitivity for full coverage restorations.

NCT ID: NCT04484844 Not yet recruiting - Clinical trials for Dentin Hypersensitivity

Clinical Evaluation of Efficacy of Shield Force Plus Varnish VS Sodium Fluoride on Dentin Hypersensitivity

Start date: October 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study to compare the clinical effectiveness of Shield Force Plus (SFP) versus sodium fluoride varnish in the management of hypersensitivity of cervical dentin in adult patients for 8weeks.