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Dental Pulp Necrosis clinical trials

View clinical trials related to Dental Pulp Necrosis.

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NCT ID: NCT06071663 Not yet recruiting - Clinical trials for Dental Pulp Necroses

Single and Two-visit Pulpectomy in Primary Molars

Start date: October 5, 2023
Phase: N/A
Study type: Interventional

A total of 64 primary molars of 5-8 years old children will be randomly selected from Pediatric dental clinic at Faculty of Dentistry, Mansoura University. Children will have two bilateral carious primary molars indicated for pulpectomy ; One side will be treated in one visit and the other will be treated in two visits. Clinical and radiographic evaluation for 3 , 6, 12 months

NCT ID: NCT06002646 Completed - Clinical trials for Pulp Disease, Dental

Lasers as an Alternative to Formocresol and Sodium Hypochlorite Medicaments in Pulpotomy Techniques

Start date: January 4, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to evaluate the dental lasers as an alternative of chemical medicaments used in the pulpotomy procedures. The main question it aims to answer is: • Lasers pulpotomies are a viable alternative to the standard Formocresol and Sodium Hypochlorite medicaments. All participants groups (Formocresol, Sodium Hypochlorite, Diode and Er:Cr;YSGG lasers) for pulpotomy procedure will follow the same clinical protocol, except for the techniques that will be used for hemostasis of the pulpotomies which either will be achieved by Formocresol or Sodium Hypochlorite solutions or by Diode or Erbium lasers.

NCT ID: NCT05988788 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic Tooth

Start date: October 2023
Phase: N/A
Study type: Interventional

clinically compare the intensity of post-operative pain and the amount of bacterial load reduction after using 20% Epigallocatechin-3-gallate solution during chemomechanical preparation, versus 2.5% NaOCl, in asymptomatic necrotic mandibular premolars treated in a single visit.

NCT ID: NCT05964686 Completed - Pulp Necroses Clinical Trials

The Efficacy of Laser in Root Canal Disinfection

Start date: January 1, 2022
Phase: Phase 2
Study type: Interventional

The aim of this study is to assess in vivo the efficacy of Er,Cr:YSGG/diode laser and Diode/EDTA on bacterial count in root canal treatment in an evidence-based clinical trial. The null hypothesis being tested is that there is no difference in total bacterial count reduction between conventional irrigation and the two types of lasers used. Thirty patients are equally divided into 3 separate groups : - Group A (Conventional): 2.5% NaOCL and 17% EDTA. - Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination - Group C(Combined): saline along with 17% EDTA and diode laser combination Microbiological analysis will be done for both aerobic and anaerobic bacteria using Colony forming units. All data will be collected, tabulated, summarized, and statistically analyzed.

NCT ID: NCT05775081 Completed - Necrotic Pulp Clinical Trials

Treated Dentine Matrix and Platelet Rich Fibrin in Induction of Root Formation of Non-Vital Immature Permanent Teeth

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

This study will be conducted to clinically evaluate the efficacy of human treated dentine matrix paste and Platelet rich fibrin (PRF) in induction of root formation of non-vital immature permanent teeth.

NCT ID: NCT05744661 Completed - Necrotic Pulp Clinical Trials

Mechanical Vs Chemomechanical Method For Calcium Hydroxide Removal

Start date: December 16, 2022
Phase: N/A
Study type: Interventional

Type of study: Randomised Clinical trial To compare the effectiveness of Mechanical and Chemomechanical methods in the removal of Water-based Calcium hydroxide medicament from endodontic system. Participants allocated in group A and B should be appointed for Endodontic treatment of Single rooted teeth diagnosed with Necrotic Pulp and Chronic Apical Periodontitis. In group A, Calcium hydroxide medicament will be removed by using Mechanical method while in group B, Calcium hydroxide will be removed by using Chemomechanical method.

NCT ID: NCT05739682 Not yet recruiting - Clinical trials for Dental Pulp Necrosis

Pain and Microbial Reduction of Antimicrobial Corticosteroid Mixture Versus Cryotherapy in Necrotic Teeth

MIXCRYO
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effect of antimicrobial-corticosteroid mixture and cryotherapy as final root canal irrigating solutions on post-instrumentation pain in single-canal teeth with necrotic pulps.

NCT ID: NCT05728346 Not yet recruiting - Pulp Necroses Clinical Trials

The Efficacy and Safety of Pulp Regeneration Induced by SHED Polymerization

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Dental pulp necrosis is one of the most common pathological conditions that results in tooth loss. However, regeneration of functional dental pulp has proved difficult. Therefore, the investigators conduct a single-arm study to evaluate the efficacy and safety of pulp regeneration induced by SHED mixed with hyaluronic acid polymerization in patients with pulp necrosis of permanent teeth.

NCT ID: NCT05666089 Not yet recruiting - Calcium Hydroxide Clinical Trials

Effect of N-acetylcysteine Versus Calcium Hydroxide Used as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Levels of MMP -9 in Periapical Fluids in Patients With Necrotic Pulp

Start date: February 1, 2023
Phase: Early Phase 1
Study type: Interventional

To compare the effect of N-acetylcysteine versus calcium hydroxide as intra canal medication on: - Intensity of postoperative pain. - Bacterial load reduction. - levels of MMP -9 in Periapical Fluids.

NCT ID: NCT05620147 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Apical Enlargement to Different Preparation Sizes and Tapers on Pain and Bacterial Reduction in Necrotic Pulp

Start date: January 2023
Phase: N/A
Study type: Interventional

The aim of this prospective randomized clinical trial is to evaluate the effect of different apical size and taper preparation (35. 04; 35. 06; 45. 04 and 45. 06) on postoperative pain at 6, 12, 24, 48 and 72 hours, and intra-canal bacterial count in patients having mandibular premolars with necrotic pulps.