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Pulp Necroses clinical trials

View clinical trials related to Pulp Necroses.

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NCT ID: NCT06256250 Active, not recruiting - Pulp Necroses Clinical Trials

Assessment of Post-operative Pain After Different Instrumentation Techniques in Pulpectomy Treatment of Primary Molars

Start date: August 10, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the post operative pain after using three different instrumentation techniques in pulpectomy treatment of pediatric participant. The main question it aims to answer: If different instrumentation techniques will affect the post operative pain in pulpectomy treatment of primary molars ? Participants will evaluate the pain using Modified Wong baker pain rating scale. Researchers will compare [ the adaptive XP endo shaper, Fanta AF baby files, and hand K files] to see if they will affect the post operative pain.

NCT ID: NCT06227533 Completed - Pulp Necroses Clinical Trials

Comparison Between Two Regenerative Scaffolds

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

This study was performed to compare endodontic regeneration outcome in necrotic mature single rooted teeth with periapical radiolucency using platelet rich fibrin (PRF) & concentrated growth factor (CGF) as a different natural scaffold by evaluation of: - Regaining pulp sensibility by thermal test (hot and cold) - Periapical healing using digital radiography and selected samples will be evaluated using Cone Beam Computed Tomography (CBCT).

NCT ID: NCT06173648 Completed - Pulp Necroses Clinical Trials

Histopathological Evaluation of the Periodontal Ligament Subjected to Laser Ablation.

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Laser Ablation therapy (LA) using an 810nm diode laser and Indocyanine Green (ICG) solution, which efficiently absorbs laser energy and increases the effectiveness of tissue removal. Intracanal heating can potentially cause damage to structures outside the tooth root. The study was to observe possible changes in the periodontal ligament and cementum resulting outside the root using this treatment. Histological and morphological examination of extracted cementum, ligament, and collagen post-exposure showed no difference in these structures vs. non-treated controls.

NCT ID: NCT06142799 Recruiting - Clinical trials for Irreversible Pulpitis

Influence of Moment of Restoration in Pain After a Root Canal Treatment

Start date: November 14, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to compare immediate placement of an overlay after root canal treatment with delayed placement of the overlay leaving the tooth one week in infra occlusion. The main question it aims to answer are: type of study: clinical trial participant population/health conditions: patients more that 18 years old who need a root canal treatment in posterior teeth with antagonist teeth. question 1: postoperative pain after 6 hours question 2: postoperative pain after 12 hours question 3: postoperative pain after 24 hours question 4: postoperative pain after 48 hours question 4: postoperative pain after 72 hours If there is a comparison group: Researchers will compare immediate overlay placement and delayed (1 week) overlay placement after root canal treatment to see if there is more pain in one group than in the other.

NCT ID: NCT06129643 Completed - Clinical trials for Apical Periodontitis

Post-operative Pain After Laser Root Canal Treatment of Necrotic Teeth With Apical Periodontitis

Start date: January 1, 2022
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate in vivo the post operative pain after laser root canal treatment in necrotic teeth in an evidence-based clinical trial. The null hypothesis being tested is that there is no difference in post operative pain between conventional irrigation and the two types of lasers used. Thirty patients are equally divided into 3 separate groups : - Group A (Conventional): 2.5% NaOCL and 17% EDTA. - Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination - Group C(Combined): saline along with 17% EDTA and diode laser combination Each patient is given pain scale chart Numeric Rating Scale (NRS) to record his/her pain level before any endodontic treatment. All data will be collected, tabulated, summarized, and statistically analyzed.

NCT ID: NCT05964686 Completed - Pulp Necroses Clinical Trials

The Efficacy of Laser in Root Canal Disinfection

Start date: January 1, 2022
Phase: Phase 2
Study type: Interventional

The aim of this study is to assess in vivo the efficacy of Er,Cr:YSGG/diode laser and Diode/EDTA on bacterial count in root canal treatment in an evidence-based clinical trial. The null hypothesis being tested is that there is no difference in total bacterial count reduction between conventional irrigation and the two types of lasers used. Thirty patients are equally divided into 3 separate groups : - Group A (Conventional): 2.5% NaOCL and 17% EDTA. - Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination - Group C(Combined): saline along with 17% EDTA and diode laser combination Microbiological analysis will be done for both aerobic and anaerobic bacteria using Colony forming units. All data will be collected, tabulated, summarized, and statistically analyzed.

NCT ID: NCT05728346 Not yet recruiting - Pulp Necroses Clinical Trials

The Efficacy and Safety of Pulp Regeneration Induced by SHED Polymerization

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Dental pulp necrosis is one of the most common pathological conditions that results in tooth loss. However, regeneration of functional dental pulp has proved difficult. Therefore, the investigators conduct a single-arm study to evaluate the efficacy and safety of pulp regeneration induced by SHED mixed with hyaluronic acid polymerization in patients with pulp necrosis of permanent teeth.

NCT ID: NCT05305417 Not yet recruiting - Periapical Diseases Clinical Trials

Cell-free Autologous Regenerative Endodontics Treatment for Teeth With Periapical Lesions (CARETT)

CARETT
Start date: March 2023
Phase: N/A
Study type: Interventional

Conventional endodontic treatment has been the treatment of choice for the management of signs and symptoms of mature permanent teeth with pulpal necrosis and periapical lesion with predictable and favorable results. However, treatment outcomes have not shown improvement or innovation in decades. The main objective of this study is to evaluate the clinical effectiveness of a regenerative endodontic procedure (cell-free and autologous protocol) versus conventional endodontics in the resolution of signs and symptoms of periapical lesion and pulp vitality-sensitivity in mature permanent teeth with a diagnosis of pulpal necrosis and periapical lesion.

NCT ID: NCT05230797 Not yet recruiting - Pulp Necroses Clinical Trials

Zincoxide-propolis vs Zincoxide-eugenol Pulpectomy

Start date: April 2022
Phase: Early Phase 1
Study type: Interventional

The clinical trial aims to evaluate the clinical and radiographic success of Zinc oxide- propolis versus Zinc oxide -Eugenol as obturating material in pulpectomy of non-vital primary teeth.

NCT ID: NCT05181813 Completed - Pulp Necroses Clinical Trials

Treatment of Infected Pulp in Primary Teeth With a Mixture of Calcium Hydroxide and Gingerols

Start date: October 17, 2020
Phase: N/A
Study type: Interventional

This study was conducted to evaluate Calcium Hydroxide mixed with Gingerols versus Metapex in treatment of primary teeth with infected necrotic pulp