Clinical Trials Logo
  1. Home
  2. Necrotic Pulp
  3. NCT05988788

Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic Tooth

Necrotic Pulp Clinical Trial

Official title:
Effect of Epigallocatechin-3-Gallate Solution Versus Sodium Hypochlorite as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Asymptomatic Necrotic Mandibular Premolars: A Randomized Clinical Trial

Clinical Trial Summary

clinically compare the intensity of post-operative pain and the amount of bacterial load reduction after using 20% Epigallocatechin-3-gallate solution during chemomechanical preparation, versus 2.5% NaOCl, in asymptomatic necrotic mandibular premolars treated in a single visit.

Clinical Trial Description

The patients will be randomly divided into 2 groups. Intervention group (20% epigallocatechin-3-gallate solution root canal irrigant) and control group (2.5% sodium hypochlorite root canal irrigant). Post-operative pain will be measured at 6, 12, 24 and 48 hours post-operatively. The pain will be recorded using the Numerical Rating Scale (NRS). Amount of bacterial load reduction The intracanal bacterial load reduction will be determined using agar culture technique by counting the colony forming units per milliliter (CFUs/mL) before and after root canal preparation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05988788
Study type Interventional
Source Cairo University
Contact rayan adlan, BDS
Phone +201117801699
Email rayan.elsadig@dentistry.cu.edu.eg
Status Not yet recruiting
Phase N/A
Start date October 2023
Completion date October 2024
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT04035330 - Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative Pain N/A
Not yet recruiting NCT05522270 - Concentrated Growth Factor Versus Platelet Rich Fibrin in Revitalization of Necrotic Young Permanent Incisors N/A
Completed NCT04606719 - Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical Periodontitis N/A
Completed NCT04983524 - Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp N/A
Not yet recruiting NCT06116214 - Effect of Vachellia Nilotica Versus Sodium Hypochlorite as Root Canal Irrigant on Postoperative Pain and Bacterial Load Reduction in Mandibular Premolar Teeth With Necrotic Pulp Phase 4
Not yet recruiting NCT03698188 - Comparative Evaluation of the Regenerative Capacity of Two Platelet Concentrates N/A
Not yet recruiting NCT05289843 - Rosmarinus Officinalis Versus 2.5%Sodium Hypochlorite as Root Canal Irrigants N/A
Not yet recruiting NCT06310044 - Effect of Commiphora Myrrh Solution as a Root Canal Irrigant on Post Operative Pain and Bacterial Load Reduction in Necrotic Tooth N/A
Completed NCT03084601 - Evaluation of Postoperative Pain After Using 3MIX-TATIN Versus Calcium Hydroxide Iodoform Paste In Necrotic Primary Molars Treated by Lesion Sterilization and Tissue Repair Therapy Phase 4
Not yet recruiting NCT03059290 - Incidence of Post-Operative Pain After Single Visit Root Canal Treatment in Necrotic Teeth Using Two Different Rotary Systems (Protaper Nex t& Neolix File) N/A
Completed NCT04646538 - Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography Early Phase 1
Completed NCT03708081 - Comparative Evaluation of Different File Systems in Postoperative Pain
Not yet recruiting NCT05419752 - Clinical Assessment of 3 Differant Obturation Sealers on Postoprative Pain and Swelling Phase 2/Phase 3
Completed NCT05775081 - Treated Dentine Matrix and Platelet Rich Fibrin in Induction of Root Formation of Non-Vital Immature Permanent Teeth N/A
Not yet recruiting NCT03009006 - Post Operative Pain and Level of Endotoxins With Calcium Hydroxide and Calcium Hydroxide Mixed With Chlorhexidine in Treating Necrotic Teeth N/A
Not yet recruiting NCT05620147 - Effect of Apical Enlargement to Different Preparation Sizes and Tapers on Pain and Bacterial Reduction in Necrotic Pulp N/A
Not yet recruiting NCT05146713 - Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars Phase 2/Phase 3
Not yet recruiting NCT04035070 - Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria Phase 4
Not yet recruiting NCT04728386 - Postoperative Pain and Antibacterial Efficacy After Root Canal Irrigation With Curcumin or Sodium Hypochlorite N/A
Not yet recruiting NCT03301259 - Postoperative Pain Following Treatment of Asymptomatic Necrotic Mandibular Molars in Single Visit Using Wave-one Reciprocating Instruments Versus One-Shape Rotary Instruments N/A