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Dental Pulp Necrosis clinical trials

View clinical trials related to Dental Pulp Necrosis.

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NCT ID: NCT06310044 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Commiphora Myrrh Solution as a Root Canal Irrigant on Post Operative Pain and Bacterial Load Reduction in Necrotic Tooth

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

Clinically compare the post-operative pain , incidences post-operative swelling , post-operative number of analgesic tablets taken by patient and amount of bacterial load reduction after using 50% Commiphora Myrrh Chemomechanical preparation , versus 2.5% NaOCl,in asymptomatic necrotic mandibular premolar treated in single visit.

NCT ID: NCT06309095 Not yet recruiting - Clinical trials for Dental Pulp Necrosis

Investigation of the Effect of Low Torque and Speed on Post-Operative Pain After Root Canal Treatment

Start date: March 15, 2024
Phase: N/A
Study type: Interventional

Root canal preparation is one of the most important stages in root canal treatment. Nowadays, the use of Nickel-Titanium(Ni-Ti) rotary instrument systems for root canal expansion is becoming very popular. The force required to rotate the Ni-Ti file is defined as the torque force and is considered a parameter for the stress produced within the canal. Ni-Ti rotary instruments can be used with a wide speed scale between 150 rpm (rotary per minute) and 40,000 rpm in conventional endodontic engines. Low torque and speed values mean low pressure applied by the instruments in the root canal. With low forces and vibrations, motor noise is generally negligible, and the instruments can easily shape most root canals in a reasonable amount of time and with minimal mechanical stress (in medium-easy canals). The use of lower torque values has been shown to reduce cyclic fatigue of Ni-Ti rotary tools. With reduced cyclic fatigue, the risk of instrument breakage in complex root canal morphologies is minimized and complications that may occur during root canal treatment are reduced. However, with low torque and speed values, cutting efficiency decreases and the process time increases as the instrument advances in the canal and during possible treatment. Decreasing cutting efficiency may also result in the operator applying force to move through the canal. With the applied force, the friction resistance within the canal increases and the heat produced increases. For this reason, it is thought that the risk of post-operative pain may increase during or after the procedure. The aim of this study is to investigate the incidence of post-operative pain and procedure time using the visual analog scale (VAS) among groups where low torque and speed values were applied during the use of the Ni-Ti rotary instrument system.

NCT ID: NCT06116214 Not yet recruiting - Post Operative Pain Clinical Trials

Effect of Vachellia Nilotica Versus Sodium Hypochlorite as Root Canal Irrigant on Postoperative Pain and Bacterial Load Reduction in Mandibular Premolar Teeth With Necrotic Pulp

Start date: November 2023
Phase: Phase 4
Study type: Interventional

The aim of this study is to assess the effect of V. nilotica extract solution versus 2.5% NaOCl on the intensity of postoperative pain and the amount of bacterial load reduction.

NCT ID: NCT06071663 Not yet recruiting - Clinical trials for Dental Pulp Necroses

Single and Two-visit Pulpectomy in Primary Molars

Start date: October 5, 2023
Phase: N/A
Study type: Interventional

A total of 64 primary molars of 5-8 years old children will be randomly selected from Pediatric dental clinic at Faculty of Dentistry, Mansoura University. Children will have two bilateral carious primary molars indicated for pulpectomy ; One side will be treated in one visit and the other will be treated in two visits. Clinical and radiographic evaluation for 3 , 6, 12 months

NCT ID: NCT05988788 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic Tooth

Start date: October 2023
Phase: N/A
Study type: Interventional

clinically compare the intensity of post-operative pain and the amount of bacterial load reduction after using 20% Epigallocatechin-3-gallate solution during chemomechanical preparation, versus 2.5% NaOCl, in asymptomatic necrotic mandibular premolars treated in a single visit.

NCT ID: NCT05739682 Not yet recruiting - Clinical trials for Dental Pulp Necrosis

Pain and Microbial Reduction of Antimicrobial Corticosteroid Mixture Versus Cryotherapy in Necrotic Teeth

MIXCRYO
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effect of antimicrobial-corticosteroid mixture and cryotherapy as final root canal irrigating solutions on post-instrumentation pain in single-canal teeth with necrotic pulps.

NCT ID: NCT05728346 Not yet recruiting - Pulp Necroses Clinical Trials

The Efficacy and Safety of Pulp Regeneration Induced by SHED Polymerization

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Dental pulp necrosis is one of the most common pathological conditions that results in tooth loss. However, regeneration of functional dental pulp has proved difficult. Therefore, the investigators conduct a single-arm study to evaluate the efficacy and safety of pulp regeneration induced by SHED mixed with hyaluronic acid polymerization in patients with pulp necrosis of permanent teeth.

NCT ID: NCT05666089 Not yet recruiting - Calcium Hydroxide Clinical Trials

Effect of N-acetylcysteine Versus Calcium Hydroxide Used as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Levels of MMP -9 in Periapical Fluids in Patients With Necrotic Pulp

Start date: February 1, 2023
Phase: Early Phase 1
Study type: Interventional

To compare the effect of N-acetylcysteine versus calcium hydroxide as intra canal medication on: - Intensity of postoperative pain. - Bacterial load reduction. - levels of MMP -9 in Periapical Fluids.

NCT ID: NCT05620147 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Apical Enlargement to Different Preparation Sizes and Tapers on Pain and Bacterial Reduction in Necrotic Pulp

Start date: January 2023
Phase: N/A
Study type: Interventional

The aim of this prospective randomized clinical trial is to evaluate the effect of different apical size and taper preparation (35. 04; 35. 06; 45. 04 and 45. 06) on postoperative pain at 6, 12, 24, 48 and 72 hours, and intra-canal bacterial count in patients having mandibular premolars with necrotic pulps.

NCT ID: NCT05582421 Not yet recruiting - Clinical trials for Apical Periodontitis

Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.

Start date: December 2022
Phase: Early Phase 1
Study type: Interventional

the aim of this study is to compare the effect of using Diclofenac Sodium Versus Calcium Hydroxide as Intracanal medication on intensity of postoperative pain, bacterial load reduction after root canal preparation and periapical matrix metalloproteinase 9 level (MMP-9) post-instrumentation and pre-obturation in teeth with necrotic pulp