Clinical Trials Logo

Dental Pulp Necrosis clinical trials

View clinical trials related to Dental Pulp Necrosis.

Filter by:
  • Completed  
  • Page 1 ·  Next »

NCT ID: NCT06291623 Completed - Clinical trials for Bacterial Viability of Necrotic Pulp With Asymptomatic Apical Periodontitis

Molecular Analysis of Intracanal Microbes After Chemomechanical Procedure and Root Canal Medication: Clinical Study

Start date: May 3, 2022
Phase: Phase 1
Study type: Interventional

This study aimed to evaluate clinically the intracanal microbes at molecular level after using established root canal medicament Calcium hydroxide and potential root canal medicament Glycyrrhizin.and Decontamination Analysis of Controls samples.

NCT ID: NCT06227533 Completed - Pulp Necroses Clinical Trials

Comparison Between Two Regenerative Scaffolds

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

This study was performed to compare endodontic regeneration outcome in necrotic mature single rooted teeth with periapical radiolucency using platelet rich fibrin (PRF) & concentrated growth factor (CGF) as a different natural scaffold by evaluation of: - Regaining pulp sensibility by thermal test (hot and cold) - Periapical healing using digital radiography and selected samples will be evaluated using Cone Beam Computed Tomography (CBCT).

NCT ID: NCT06173648 Completed - Pulp Necroses Clinical Trials

Histopathological Evaluation of the Periodontal Ligament Subjected to Laser Ablation.

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Laser Ablation therapy (LA) using an 810nm diode laser and Indocyanine Green (ICG) solution, which efficiently absorbs laser energy and increases the effectiveness of tissue removal. Intracanal heating can potentially cause damage to structures outside the tooth root. The study was to observe possible changes in the periodontal ligament and cementum resulting outside the root using this treatment. Histological and morphological examination of extracted cementum, ligament, and collagen post-exposure showed no difference in these structures vs. non-treated controls.

NCT ID: NCT06129643 Completed - Clinical trials for Apical Periodontitis

Post-operative Pain After Laser Root Canal Treatment of Necrotic Teeth With Apical Periodontitis

Start date: January 1, 2022
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate in vivo the post operative pain after laser root canal treatment in necrotic teeth in an evidence-based clinical trial. The null hypothesis being tested is that there is no difference in post operative pain between conventional irrigation and the two types of lasers used. Thirty patients are equally divided into 3 separate groups : - Group A (Conventional): 2.5% NaOCL and 17% EDTA. - Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination - Group C(Combined): saline along with 17% EDTA and diode laser combination Each patient is given pain scale chart Numeric Rating Scale (NRS) to record his/her pain level before any endodontic treatment. All data will be collected, tabulated, summarized, and statistically analyzed.

NCT ID: NCT06002646 Completed - Clinical trials for Pulp Disease, Dental

Lasers as an Alternative to Formocresol and Sodium Hypochlorite Medicaments in Pulpotomy Techniques

Start date: January 4, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to evaluate the dental lasers as an alternative of chemical medicaments used in the pulpotomy procedures. The main question it aims to answer is: • Lasers pulpotomies are a viable alternative to the standard Formocresol and Sodium Hypochlorite medicaments. All participants groups (Formocresol, Sodium Hypochlorite, Diode and Er:Cr;YSGG lasers) for pulpotomy procedure will follow the same clinical protocol, except for the techniques that will be used for hemostasis of the pulpotomies which either will be achieved by Formocresol or Sodium Hypochlorite solutions or by Diode or Erbium lasers.

NCT ID: NCT05964686 Completed - Pulp Necroses Clinical Trials

The Efficacy of Laser in Root Canal Disinfection

Start date: January 1, 2022
Phase: Phase 2
Study type: Interventional

The aim of this study is to assess in vivo the efficacy of Er,Cr:YSGG/diode laser and Diode/EDTA on bacterial count in root canal treatment in an evidence-based clinical trial. The null hypothesis being tested is that there is no difference in total bacterial count reduction between conventional irrigation and the two types of lasers used. Thirty patients are equally divided into 3 separate groups : - Group A (Conventional): 2.5% NaOCL and 17% EDTA. - Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination - Group C(Combined): saline along with 17% EDTA and diode laser combination Microbiological analysis will be done for both aerobic and anaerobic bacteria using Colony forming units. All data will be collected, tabulated, summarized, and statistically analyzed.

NCT ID: NCT05775081 Completed - Necrotic Pulp Clinical Trials

Treated Dentine Matrix and Platelet Rich Fibrin in Induction of Root Formation of Non-Vital Immature Permanent Teeth

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

This study will be conducted to clinically evaluate the efficacy of human treated dentine matrix paste and Platelet rich fibrin (PRF) in induction of root formation of non-vital immature permanent teeth.

NCT ID: NCT05744661 Completed - Necrotic Pulp Clinical Trials

Mechanical Vs Chemomechanical Method For Calcium Hydroxide Removal

Start date: December 16, 2022
Phase: N/A
Study type: Interventional

Type of study: Randomised Clinical trial To compare the effectiveness of Mechanical and Chemomechanical methods in the removal of Water-based Calcium hydroxide medicament from endodontic system. Participants allocated in group A and B should be appointed for Endodontic treatment of Single rooted teeth diagnosed with Necrotic Pulp and Chronic Apical Periodontitis. In group A, Calcium hydroxide medicament will be removed by using Mechanical method while in group B, Calcium hydroxide will be removed by using Chemomechanical method.

NCT ID: NCT05611736 Completed - Post Operative Pain Clinical Trials

Effects of Intracanal Cryotherapy on Endodontic Postoperative Pain

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effect of cold saline (2.5 degrees Celsius) irrigation on postoperative pain in patients who require root canal treatment in molar teeth because of dead dental pulp and infection around the apex of the root of the involved teeth. This cold saline irrigation will be done after standard irrigation of the canal using a 5.25% sodium hypochlorite solution. The main questions it aims to answer are: - Is there any difference in postoperative pain when final irrigation is performed using a cold saline solution compared to the irrigation using the saline solution at room temperature in patients who require dental root canal treatment of molar teeth? - Because of cold saline irrigation, what type of adverse event/s may result? Participants will be asked to fill out a questionnaire before the start of the root canal treatment and record the preoperative pain using the visual analog scale (VAS). Root canal treatment will be completed in one visit. The standard procedure of root canal treatment will be followed, including irrigation of the canal using 5.25% sodium hypochlorite. As a final irrigation, either cold saline solution or a normal saline solution at room temperature will be used. The participants will be asked to fill out another questionnaire and record the presence, duration, and intensity of postoperative pain, and if painkiller medicine was taken immediately after completion of root canal treatment and at 6 hours, 12 hours, 72 hours, and 1-week intervals. The researcher will compare the effect of the final irrigation of a cold saline solution with that of a normal saline solution at room temperature on postoperative pain.

NCT ID: NCT05445362 Completed - Clinical trials for Effects of the Elements

Efficacy of Diode Laser in Maturogenesis of Immature Teeth With Necrotic Pulps

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Recruited patients with immature permanent maxillary anterior teeth with non-vital pulp, and periapical radiolucency, age ranging from 8 to16 years old were randomly allocated into three groups (n=13): Group I, disinfected using the triple antibiotic paste, Group II, disinfection was done using diode laser, and Group III, were disinfected using the triple antibiotic paste, diode laser was used for biostimulation. All groups were evaluated for the increase in root length and thickness and decrease in apical diameter at baseline, 3, 6, 9, and 12 months after treatment