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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT06145386 Active, not recruiting - COVID-19 Clinical Trials

"The Effect of Aerobic Exercise and Strength Training on Physical Activity Level, Quality of Life and Anxiety-Stress Disorder in Young Adults With and Without Covid-19"

Start date: February 21, 2022
Phase: N/A
Study type: Interventional

The purpose of this study; to examine the effects of aerobic and strength training on physical activity level, quality of life and anxiety-stress disorder in young adults with and without COVID-19. In this context, the study was planned by including 15 participants between the ages of 18-25 who had COVID-19 and 15 who did not have COVID-19. Data were collected by applying the Personal Data Form, IPAQ (International Physical Activity Form), SF-36 Quality of Life Scale, Coronavirus Anxiety Scale (CCS), Respiratory Function Tests (PFT), Six Minute Walk Test (6MWT). Aerobic training and strengthening training were applied to people with and without COVID-19 for 12 weeks. Aerobic exercise (walking) was given for 40 minutes 5 days a week, with the target heart rate being 70% of the age-corrected maximum heart rate. Strengthening exercises were applied to the upper (triceps, biceps, deltoid, pectorals) and lower (quadriceps, hamstring, gastrocnemius, tibialis anterior, hip adductors, hip flexors, hip extensors) extremities and back muscles (trapezius, latissimus dorsi) with theraband (resistance band). Significance test of the difference between two means in comparing independent group differences when parametric test assumptions are met for statistical analysis in line with the data collected from the participants; When parametric test assumptions are not met, Mann Whitney U test is used to compare independent group differences, while when parametric test assumptions are met to examine dependent group differences, the significance test of the difference between the two spouses is used; When parametric test assumptions were not met, the Wilcoxon paired two sample test was used. In all analyses, p < .05 was considered statistically significant.

NCT ID: NCT06107348 Active, not recruiting - Clinical trials for Immune System Diseases

COVID-19 Post-Vaccination Observation

Start date: July 1, 2021
Study type: Observational

The study started after the second COVID-19 vaccination of the participant with blood spots appearing on the skin with severe arthritis. The study continued to the third-dose full vaccination of the participant with the recombined COVID-19 vaccination and afterwards. The study completed until intervention.

NCT ID: NCT06099626 Active, not recruiting - Clinical trials for Autoimmune Liver Disease, COVID-19

Study of Clinical Features of Patients With Autoimmune Liver Disease Complicated With Covid-19 and the Immune Mechanism Affecting Prognosis

Start date: January 1, 2023
Study type: Observational

With the decreasing virulence of omicrons strain, the current domestic epidemic prevention policy has been changed based on the health of the people and the development needs of the country. At present, the infection rate of the novel coronavirus in China is rising rapidly. Previous studies have found that patients with chronic liver disease are more likely to be co-infected with coronavirus disease 2019 and have a worse prognosis. Based on its unique immune mechanism and therapeutic drugs, patients with autoimmune liver disease also have very different manifestations after infection with the novel coronavirus. By observing the clinical characteristics and prognosis of patients with autoimmune liver disease complicated with coronavirus disease 2019, this study analyzed the roles of vaccines, immunosuppressive agents and ursodeoxycholic acid , and explored the immune mechanism behind them, so as to seek new anti-coronavirus disease 2019 drugs and provide new strategies for clinical prevention and treatment.

NCT ID: NCT06091293 Active, not recruiting - Long COVID Clinical Trials

Narrative Intervention for Long COVID-19 (NICO)

Start date: October 11, 2022
Phase: N/A
Study type: Interventional

This T1 proof of concept trial is designed to test the Narrative Intervention for Long COVID-19 intervention.

NCT ID: NCT06070896 Active, not recruiting - COVID-19 Clinical Trials

Advanced Modeling of the Evolution of the Epidemiological Outbreak of SARS-CoV-2 Pandemic

Start date: March 1, 2020
Study type: Observational

The various epidemics that health systems periodically suffers require having valid and detailed information on its evolution and predictions in the short, medium and long term in real time to allow the health system to organize itself in advance to be able to address the health and sanitary problem that this entails.The objectives of this proposal are: to study the usefulness of the health system's information and data storage system as a source for quickly and efficiently obtaining data necessary for modeling an epidemiological outbreak; its modeling in order to predict its evolution and the presentation of results to help in decision making. The investigatorswill rely on the experience obtained so far during the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, to define semi-automatic and flexible criteria for searching, extracting, cleaning and aggregating data. Predictions of incidence, number of hospital and ICU admissions, and number of deaths will be made at the Basque Country level.Within the analysis of temporal data, especially in the context of the pandemic, it is essential to have robust tools that allow accurate predictions. In this study, the investigators employed P-splines based on the negative binomial distribution to predict pandemic-related positive cases, hospital admissions, and ICU admissions.

NCT ID: NCT06042790 Active, not recruiting - Quality of Life Clinical Trials

Patients´ Mental and Physical Health After Covid-19 Treated in ICU in Sweden

Start date: March 1, 2020
Study type: Observational

Covid-19 is a disease where both clinical experience and thus knowledge about the long-term effects of the disease are currently sparse. However, current follow-up results indicate a more pronounced cognitive and respiratory impairment than previously seen in a normal ICU population. As we know that the prevalence of impairments in neurocognitive and Health Related Quality of Life (HRQoL) is increased in a majority of ICU patients, it would be of benefit to gain knowledge about the impact on the recovery trajectory for patients treated for Covid-19, and to increase the understanding of which factors that affect the HRQoL and recovery and in what way these differs between patients treated in ICU for Covid-19 and other causes respectively. This can contribute to better structures for follow-up and possibility to individualisation that better address which patients are in risk for decreased HRQoL and where benefit for the patient, health care and social economic can be achieved.

NCT ID: NCT06039449 Active, not recruiting - COVID-19 Clinical Trials

A Study to Investigate the Prevention of COVID-19 withVYD222 in Adults With Immune Compromise and in Participants Aged 12 Years or Older Who Are at Risk of Exposure to SARS-CoV-2

Start date: September 8, 2023
Phase: Phase 3
Study type: Interventional

A study to investigate the prevention of COVID-19 with VYD222 in adults with immune compromise and in participants aged 12 years or older who are at risk of exposure to SARS-CoV-2

NCT ID: NCT06037707 Active, not recruiting - Clinical trials for COVID-19-Associated Thromboembolism

Thromboembolic Complications in COVID-19 Patients in Intensive Care Unit

Start date: January 1, 2022
Study type: Observational

The present study aims to determine frequency of thromboembolic complications and the underlying causes of this complication of the patients who admitted to the intensive care unit diagnosed with COVID-19.

NCT ID: NCT06033560 Active, not recruiting - COVID-19 Clinical Trials

The Effect of Non-invasive Respiratory Support on Outcome and Its Risks in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2)-Related Hypoxemic Respiratory Failure

Start date: September 6, 2022
Study type: Observational

Coronavirus disease (COVID-19) can result in severe hypoxemic respiratory failure that ultimately may require invasive mechanical ventilation in the Intensive Care Unit (ICU). Although lifesaving, invasive mechanical ventilation is associated with high mortality, severe discomfort for patient, long-term sequelae, stress to loved-ones and high costs for society. During the ongoing pandemic high number of invasively ventilated COVID-19 patients overwhelmed ICU capacity. Non-invasive respiratory support, such as high flow nasal oxygen (HFNO) or non-invasive ventilation (NIV) have the potential to reduce the risk for invasive mechanical ventilation and in selected cases ICU admission. However, data from different studies are conflicting and studies performed in COVID-19 patients are of limited quality. Furthermore, identification of early predictors of HFNO/NIV treatment failure may prevent unnecessary delay of initiation of invasive ventilation, which may be associated with adverse clinical outcome. The development and validation of a prediction model, that incorporates readily available clinically data may prove pivotal to fine-tune non-invasive respiratory support. The overall aim of the NORMO2 project is to investigate the role and risks of HFNO and NIV to improve outcome in hospitalized hypoxemic COVID-19 patients.

NCT ID: NCT06018649 Active, not recruiting - COVID-19 Clinical Trials

The Effectiveness of Natural Resources for Reducing Stress

Start date: January 2, 2023
Phase: N/A
Study type: Interventional

High levels of stress cause serious health problems and reduce the quality of life. There is a lack of research proving the use of natural resources for the treatment or prevention of the stress and recovery from post Covid-19 condition. The goal of research: to assess the impact of natural resources (geothermal/mineral water, mud, salt, climate) on reducing stress and improving stress-related mental and physical health, as well as the safety of the procedures. The study will be randomized, controlled, parallel group, single- blinded (to researchers). The complex of procedures of water pool, mineral water bath, mud wrapping, salt therapy, nature therapy procedure will be provided with the different duration and mode (inpatient, outpatient). Primary outcomes- the effect on stress level; secondary outcomes: the effects on stress-related mental and physical health, work and social adaptation, tolerance and safety of balneotherapy procedures. The observation: before, after treatment, after 3 and 6 month of follow-up will be reveled.