Clinical Trials Logo

Covid19 clinical trials

View clinical trials related to Covid19.

Filter by:

NCT ID: NCT06141837 Not yet recruiting - COVID-19 Clinical Trials

Pseudomonas Aeruginosa Infections Among COVID-19 Patients in Intensive Care Units at CHRU of Nancy (Pyo-COVID-3)

Start date: December 1, 2023
Study type: Observational

P. aeruginosa is an opportunistic bacterium known to be responsible for numerous healthcare-associated infections, particularly in intensive care units (ICU). The frequency of these infections seems to have increased during the first waves of the COVID-19 pandemic. Identifying cases of co-infection and secondary infections with P. aeruginosa in patients with COVID-19 would provide a better understanding of the epidemiological evolution and characteristics of infected patients. Treatment of P. aeruginosa infections requires the use of antibiotics. Antibiotic resistance is a growing problem, with an increase in resistance among P. aeruginosa strains. The misuse of antibiotics to treat patients can accentuate the phenomenon of antibiotic resistance, and failure to take account of resistance revealed by antibiograms can compromise patient recovery. Analysis of bacteriological results and patient medical records would enable a posteriori evaluation of the proper use of antibiotics (choice and adaptation of molecules, doses and duration of prescriptions), and identify any areas for improvement. The main objective is to describe the evolution of P. aeruginosa infections in ICU patients with COVID-19 during the first 3 waves of COVID-19 (01/03/2020 to 31/05/2021). Secondary objectives are to describe the typology of P. aeruginosa strains identified among included patients (sampling sites and resistance profiles), to assess antibiotic prescriptions for these patients and to describe the relapse rate of included patients with a first P. aeruginosa infection.

NCT ID: NCT06141824 Completed - COVID-19 Clinical Trials

Performance Evaluation of the Lucira COVID-19 & Flu Test

Start date: October 11, 2022
Phase: N/A
Study type: Interventional

The Lucira COVID-19& Flu Test is a real-time RT-LAMP test intended for the qualitative detection and differentiation of RNA from SARS-CoV-2, Influenza A and Influenza B in self-collected nasal swab samples. The test consists of a nasal swab, a sample vial the nasal swab sample is placed in to prepare the sample for testing, and a test unit which detects whether SARS-CoV-2, Influenza A, and Influenza B virus is present within the specimen. The Lucira test uses a proprietary, molecular based detection process to detect whether a person is actively shedding the genomic RNA from the SARS-CoV-2, Influenza A, or Influenza B virus. The purpose of this study is to investigate the Lucira COVID-19& Flu Test for the in vitro qualitative detection and differentiation of RNA from SARS-CoV-2, Influenza A, and Influenza B in nasal swab specimens from patients suspected of COVID-19 or Influenza A or Influenza B. The primary objective is to test at least 1000 self-collected nasal swab samples for SARS-CoV-2 and Influenza A&B as compared to FDA cleared/authorized SARS-CoV-2 and Influenza A&B Assays.

NCT ID: NCT06137716 Completed - Clinical trials for Post-acute Covid-19 Syndrome

Robotic Assisted Hand Rehabilitation Outcomes in Adults After COVID-19

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Prolonged hospitalization in severe COVID-19 cases can lead to substantial muscle loss and functional deterioration. While rehabilitation is vital, conventional approaches encounter capacity constraints. Therefore, assessing the efficacy of robotic-assisted rehabilitation is crucial for post-COVID-19 fatigue syndrome patients, aiming to improve motor function and overall recovery. The study focuses on evaluating rehabilitation effectiveness in individuals with upper-extremity impairment using a hand exoskeleton-based robotic system.

NCT ID: NCT06137001 Completed - COVID-19 Clinical Trials

Safety and Immunogenicity of BNT162b2 Coadministered With SIIV in Adults 18 Through 64 Years of Age

Start date: April 20, 2022
Phase: Phase 3
Study type: Interventional

This study will assess the safety and immunogenicity of a fourth dose (booster) of BNT162b2 when coadministered with SIIV compared to separate administration of the vaccines when given 1 month apart (SIIV followed by BNT162b2), in participants who have received 3 prior doses of 30 µg BNT162b2, with the third dose being at least 90 days before Visit 1 (Day 1). - Healthy adults 18 through 64 years of age will be randomized 1:1 to either the co-administration group, or the separate administration group - The duration of the study for each participant will be approximately 2 months - There are 3 scheduled study visits each about 1 month apart - The study will be conducted in New Zealand and Australia.

NCT ID: NCT06136871 Not yet recruiting - Clinical trials for Post-COVID-19 Syndrome

Cognitive Rehabilitation in Post-COVID-19 Syndrome

Start date: December 2023
Phase: N/A
Study type: Interventional

The first aim of this study is to determine the feasibility of delivering CO-OP remotely to individuals experiencing cognitive impairments that limit everyday activities in post-COVID-19 syndrome (PCS). The second aim of this study is to assess the effect of CO-OP on activity performance, subjective and objective cognition, and quality of life in a sample of individuals with PCS. The research team hypothesizes that effect size estimations will indicate that CO-OP will have a greater positive effect, compared to an inactive control group, on activity performance, subjective and objective cognition, and quality of life in a sample of individuals who self-report PCS and cognitive impairment.

NCT ID: NCT06135623 Completed - COVID-19 Clinical Trials

Long-Term Impact of COVID-19 Restrictions on Physical Activity and Social Interactions in Young Adults

Start date: June 14, 2022
Study type: Observational

There are studies on the impact of quarantine measures taken during the COVID-19 pandemic on individuals' social interactions and physical activities. We think that the adaptation of individuals who have had COVID-19 infection to return to social and physical activities after restrictions may affect participation in these activities. The aim of this study is to investigate the long-term impact of COVID-19 restrictions on physical activity and social interaction in young adults, depending on whether they have had a COVID-19 infection.

NCT ID: NCT06135610 Completed - COVID-19 Clinical Trials

Social Determinants of Health in Patients With Penetrating Trauma Injuries Before and During the COVID-19 Pandemic

Start date: March 1, 2019
Study type: Observational

Investigators report on the impact of the COVID-19 stay-at-home order concerning penetrating violence and its association within different socioeconomic regions within the county. The distribution and volume of violent offenses prior to the stay-at-home order was compared to during the stay-at-home order. This bears a crucial significance in our injury prevention and education efforts within our community.

NCT ID: NCT06135207 Completed - COVID-19 Clinical Trials

The Correlation Between COVID-19 and Dysphagia in Adults With Swallowing Disorders

Start date: June 27, 2022
Study type: Observational

This study aims to investigate the correlation between COVID-19 and dysphagia in adults. The population of the study consisted of those who applied to Bezmialem University, Department of Otorhinolaryngology, Dysphagia Outpatient Clinic with the complaint of dysphagia. Patients older than 18 years of age, suffering from dysphagia and not having mental retardation were included in the study. Patients who did not have swallowing difficulties and refused to participate in the study were excluded.

NCT ID: NCT06134674 Completed - Clinical trials for COVID-19 Acute Respiratory Distress Syndrome

Early Versus Delayed Enteral Nutrition in Critically Ill Adults With COVID-19

Start date: October 20, 2021
Study type: Observational

The goal of this observational study is to determine the relationship between the nutritional profile of critically ill patients diagnosed with COVID-19 and disease severity, prognosis, and survival, to assess the ability to meet nutritional goals, EN complications, and reasons for discontinuation and postponement of feeding. The main questions aim to answer are the relationship between the duration of EN initiation and Prognostic Nutritional Index (PNI) score, neutrophil-lymphocyte ratio (NLR), oxygenation status, MV, ICU, and length of hospital stay, overall mortality, and whether nutritional goals were met, EN complications, and reasons for discontinuation and postponement.

NCT ID: NCT06130410 Not yet recruiting - COVID-19 Clinical Trials

Special Investigation for Booster Dose of Comirnaty in Children Ages 6 Months Though 4 Years

Start date: December 8, 2023
Study type: Observational

The purpose of this post-marketing study is to assess the safety of Comirnaty monovalent XBB.1.5. for booster vaccination children ages 6 months though 4 years under actual use medical practice.