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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT05689827 Completed - COVID-19 Clinical Trials

Safety and Efficacy of the Therapy With BREINMAX® for the Treatment of Patients With Asthenia After COVID-19

Start date: April 5, 2022
Phase: Phase 4
Study type: Interventional

This is prospective multicentre comparative randomized double blind placebo controlled study conducted in 6 medical facilities.The objective of the study is to assess the safety and efficacy of the sequential therapy with BREINMAX®, solution for intravenous infusion and intramuscular injection, and BREINMAX®, capsules for the treatment of patients with asthenia after having the novel coronavirus infection (COVID-19)

NCT ID: NCT05689229 Completed - Clinical trials for Secondary Bacterial Infection in COVID-19 Patients

Aerosolized Versus Intravenous Colistin-based Antimicrobial Regimens in Hospitalized COVID-19 Patients With Bacterial Coinfection: A Randomized Controlled Trial

colistin
Start date: August 3, 2021
Phase: Phase 3
Study type: Interventional

Secondary bacterial pathogen infection has been demonstrated to aggravate COVID-19 clinical outcomes. Bacterial infections acquired during a hospital stay are likely resistant to several antimicrobial medicines, making COVID-19 patient management difficult. As a result, it is believed that aerosolized colistin might be a viable choice for treating secondary bacterial infections caused by gram-negative resistant strains in individuals who also have COVID-19 infection.

NCT ID: NCT05689203 Recruiting - COVID-19 Clinical Trials

A Phase 2 Study to Evaluate the Efficacy and Safety of QLS1128 Orally in Symptomatic Participants With Mild to Moderate COVID-19

Start date: December 30, 2022
Phase: Phase 2
Study type: Interventional

A Phase 2 Study to Evaluate the Efficacy and Safety of QLS1128 Orally in Symptomatic Participants With Mild to Moderate COVID-19

NCT ID: NCT05689177 Enrolling by invitation - Humoral Immunity Clinical Trials

Humoral Immunity Study After Booster Vaccination of "Soberana Plus" (The Republic of Cuba) Against COVID-19

Start date: December 9, 2022
Phase: N/A
Study type: Interventional

To evaluate the dynamics of IgG levels to the SARS-CoV-2 virus after a booster dose of Soberana Plus vaccine.

NCT ID: NCT05689073 Not yet recruiting - COVID-19 Clinical Trials

A Chatbot to Enhance COVID-19 Knowledge

Start date: January 17, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to explore whether a chatbot based on NLP techniques has better educational effect than printed booklets on knowledge of COVID-19 and its vaccination.

NCT ID: NCT05689034 Not yet recruiting - Clinical trials for COVID-19 Respiratory Infection

Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 at Increased Risk of Progressing to Severe Illness

Start date: January 20, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

To investigate whether treatment with Azvudine reduces the risk of severe illness or death in patients who are at a potential risk of progressing to severe COVID-19 infection.

NCT ID: NCT05689008 Recruiting - COVID-19 Pneumonia Clinical Trials

UC-MSCs in the Treatment of Severe and Critical COVID-19 Patients With Refractory Hypoxia

Start date: January 10, 2023
Phase: Phase 3
Study type: Interventional

The goal of this randomized, controlled, open-labeled interventional clinical trial is to test the efficacy and safety of umbilical cord mesenchymal stem cells (UC- MSCs) in the treatment of severe and critical COVID-19 patients with refractory hypoxia even after sufficient standard treatment according to the tenth edition of Chinese guidelines for COVID-19 infection. The main questions it aims to answer are: 1. The efficacy of UC-MSCs in the treatment of severe and critical COVID-19 patients with refractory hypoxia. 2. The safety of UC-MSCs in the treatment of severe and critical COVID-19 patients. 3. The potential immune mechanisms of UC- MSCs in the treatment of severe and critical COVID-19 patients. Participants will receive standard therapy, or the UC-MSCs treatment. For the standard treatment, it will be conducted according the 10th edition of Chinese guidelines for severe or critical COVID-19 infection. For UC-MSCs treatment, participants will be given UC-MSCs instillation at the first and fourth day after assignment. Blood examples will be taken at indicated time for arterial blood gas analysis and other tests. And participants should also objectively report their symptoms change and other information related to the treatment as listed the research protocol.

NCT ID: NCT05687877 Recruiting - Clinical trials for SARS-CoV-2 Infection

Evusheld Japan PMS_Japan Post-Marketing Surveillance (PMS)

Start date: January 6, 2023
Phase:
Study type: Observational

To investigate intends to evaluate the incidence of adverse drug reactions (ADRs) in individuals who receive Evusheld in clinical practice to determine its post-marketing safety profile in Japanese.

NCT ID: NCT05685992 Not yet recruiting - COVID-19 Infection Clinical Trials

Novel Coronavirus Infection and Reproductive Function

Start date: January 20, 2023
Phase:
Study type: Observational [Patient Registry]

This study aims to observe the impact of COVID-19 infection on the reproductive function and assisted pregnancy outcome of infertile couples undergoing assisted reproductive technology and to determine which factors are related to the clinical pregnancy rate. A multicenter, prospective, observational cohort study was adopted. Infertile couples who met the selection criteria were included in this study, the SAS anxiety self-rating scale was filled out, the basic situation was observed, and blood samples and related tissues were collected for testing. Relevant reproductive function, laboratory, clinical, and psychological indicators were collected, and the correlation between the above indicators and the outcome of the ART-related pregnancy were analyzed.

NCT ID: NCT05685966 Not yet recruiting - COVID-19 Clinical Trials

Retrospective Study of COVID-19 on Reproductive Function

Start date: January 20, 2023
Phase:
Study type: Observational

This multi-center, retrospective cohort study aimed to determine which factors are associated with ongoing pregnancy rates in infertile patients received ART treatments during the current outbreak of COVID-19 infection.Couples who underwent IVF-ET/ICSI-ET/FET due to infertility in the department of Reproductive Medicine from 2022-11-23 to 2023-01-07 were included. Patients who were infected with Coronavirus were observation groups; the infection status and clinical outcome were tracked. Patients who were not infected with Coronavirus were control groups.