There are about 15072 clinical studies being (or have been) conducted in Turkey. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
The aim of this planned randomized controlled clinical study is to evaluate the morbidity of the palatal donor area after free gingival graft (FGG) operations. In this study, wound healing and pain levels in the palatal region will be evaluated after cyanoacrylate and concentrated growth factor (CGF) applications.
In order to determine the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are analysed in tissues and fluids taken from the body. In various publications, the role of the glycoprotein sNRP-1 on inflammatory diseases and the relationship between smoking and periodontal diseases have been investigated. In this study, our aim was to evaluate the levels of this biomarker in the saliva of smokers with systemically healthy periodontitis and non-smokers with systemically healthy periodontitis, gingivitis and periodontal disease and to compare the concentration differences with CRP. Another aim is to show the effect of nicotine exposure rate on all these by measuring cotinine levels. In our study, all oral clinical parameters of 80 patients, including 20 systemically healthy, non-smoking and periodontally healthy patients, 20 patients with gingivitis, 20 patients with periodontitis; 20 systemically healthy, smoking patients with periodontitis, will be measured and saliva samples will be taken from the patients. The sNRP-1, cotinine and CRP levels in the samples will be determined by enzyme-linked immunoassay (ELISA). Then, statistical analyses will be performed and the difference in the levels of biomarkers between the groups will be interpreted. Possible significant differences between the levels of these biomarkers may reveal that sNRP-1 can be used as a diagnostic tool in periodontal diseases or as a guide for treatments to be performed and may reveal a new perspective on the relationship between periodontitis and smoking.
Virtual Reality based training modulues have become a part of simulation based medical education and are nowadays used for undergraduate and postgraduate level training of healthcare professionals.In parallel to the advancements in Artificial Intelligence technology voice regotnition has the potential to be used as an interfeace during game play .The aim of this study is whether game interface with Artificial Intelligence based voice regognition may elevate the level of immersion during the use of Virtual Reality based serious gaming for Advanced Cardiac Life Support Training.
The aim of the study is to determine the effect of breast cancer education given to incarcerated women on breast cancer knowledge and awareness.
The primary aim is to evaluate pulmonary function, respiratory muscle strength, upper and lower extremity exercise capacity, muscle oxygenation, dyspnea, peripheral muscle strength, arterial stiffness, physical activity level and balance in children with pulmonary arterial hypertension and compare with age- and sex-matched healthy controls. The second aim is to investigate the relationship between upper extremity exercise capacity, arterial stiffness, respiratory and peripheral muscle strength
To examine the effect of acupressure therapy method applied to nursing students on exam anxiety and vital signs.
The aim of this study was to determine the impact of training provided through simulation method on self-confidence and stress levels in nursing students during patient intervention.
To examine the effects of clinical pilates exercise on glycemic control, blood lipids and physical fitness parameters in prediabetics. Subjects will be divided into two groups through randomization.Subjects in the 1st group will be included in the control group and will continue their routine. Subjects in the 2nd group will be given clinical pilates exercise training. All subjects will be evaluated at the start of treatment, and week 16.
The investigator's aim in this study was to evaluate the preoperative anxiety and pain felt during the operation due to exposure to green, red, and blue light. For this purpose, the participants will wear colored glasses before the operation. The investigator will evaluate the patient's anxiety change and the pain she/he feels during the procedure.
This study will be conducted to determine the effect of educational escape room teaching on nursing students' skills in calculating intravenous drug dosage and applying fluid therapy. The research was planned in a pretest-posttest and retest randomized controlled experimental design with a control group. This study will be conducted in the Spring Term of the 2023-2024 Academic Year at Kafkas University, Faculty of Health Sciences, Department of Nursing. 1st year and 4th year nursing students will be included in the sample of the research. Power analysis was performed to determine the number of people to be included in the study. The power of the test was calculated with the G*Power 3.1 program. Students will be divided into two groups, control and experimental, by randomization method. A total of 120 students were planned to be included in the study: 30 experimental and 30 control students for the first grade, and 30 experimental and 30 control students for the fourth grade. In order to conduct the research, written permissions were obtained from the ethics committee and the institution where the study would be conducted. The data of the research will be collected with the "Introductory Information Form-IIF", "Intravenous Drug Dosage Calculation and Fluid Therapy Application Knowledge Test-IVKT" (min:0-max:100), "Intravenous Drug Dosage Calculation and Fluid Therapy Application Skill Checklists-IVSC" (min:0-max:242) and "Game Evaluation Form-GEF" (min:26-max:130). Increasing the score obtained from data collection tools means that knowledge and skills increase.Data collection tools were presented to expert opinion for content validity. Content validity indexes were calculated and it was determined that the instruments were usable. The entire sample group will be given training on intravenous drug dose calculation and fluid therapy application. During the training, the subject will be supported by question-answer technique. Then, initial knowledge (pre-test) and initial skill (pre-test) will be measured with an objective structured clinical exam and scores will be calculated. According to the pre-test knowledge and skill scores, students from both grade levels will be assigned to experimental and control groups. The experimental group will play the escape room game in teams of five people according to the prepared educational escape room game plan. During this process, the control group will be given the right to work independently in the laboratory. The experimental group will play the educational escape room game once, and then the final knowledge (post-test) and final skills (objective structured clinical exam) of the experimental and control groups will be measured. Each student in the experimental group will be asked to fill out the game evaluation form. In evaluating the data, parametric or non-parametric tests will be used to determine whether the research data show a normal distribution or not. Correlation will be made to determine the relationship between pretest and posttest knowledge tests and objective structured clinical exam scores. Regression analysis will also be performed if necessary, based on the analysis results of the research data.