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NCT ID: NCT04989101 Recruiting - Clinical trials for COVID-19 Acute Respiratory Distress Syndrome

Nigelle 5CH in Prevention of Influanza

Start date: June 5, 2021
Phase: N/A
Study type: Interventional

This study will be carried out by more than 30 liberal Tunisian doctors, who will submit according to the inclusion / exclusion criteria of people who will receive (free of charge) a capsule of the Nig5 product sublingually, each day. Against a control group which will be followed with the same protocol as the first but which will not receive the product. Randomization (even days: nigella group, odd days: control group)

NCT ID: NCT04988711 Completed - Trauma Clinical Trials

Non-invasive Tool for Measuring Hemoglobin in Severe Trauma Patients in the ED

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

The development of miniaturized analytical technologies has facilitated the gradual decentralization of part of the laboratory examinations to the patient. In addition, investigators are currently seeing the development of tools for non-invasive measurement of certain biological parameters. Thanks to their ease of use, results are obtained almost immediately and with good performance. These "rapid" tests or techniques should, in theory, reduce the time taken to take charge of patients, particularly in emergencies or in critical situations where the therapeutic decision should be as rapid and efficient as possible. These means, by their ease and speed of results, could be associated with the clinical examination of the practitioner to increase his diagnostic performance.

NCT ID: NCT04982341 Completed - Clinical trials for Hypoxemic Respiratory Failure

HFNC and Prone Positioning in Awake Patients With Severe COVID-19

Start date: September 2, 2020
Study type: Observational

The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.

NCT ID: NCT04978025 Recruiting - Clinical trials for SARS (Severe Acute Respiratory Syndrome)

Colloidal Silver, Treatment of COVID-19

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

Noble metals such as gold and silver have been appreciated for millennia not only for their beauty but also for their ability to fight diseases. Silver nanoparticles (AgNPs) have been employed as chemical drugs thanks to their unique physiochemical and chemical properties as well as biological features, such as anti-inflammatory, anti-angiogenesis, antiplatelet, antifungal, anti-cancer and antibacterial activities I

NCT ID: NCT04961684 Completed - Clinical trials for Onychomycosis of Toenail

Clinical Evaluation of Efficacy and Safety of a Medical Device for the Treatment of Toenail Onychomycosis

Start date: February 10, 2020
Phase: N/A
Study type: Interventional

The efficacy and safety of Solver Pen (prototype number X92001704) is evaluated in this randomized, open label, controlled, investigator-blinded, comparative clinical trial in 76 patients. Subjects are treated with either the test medical device (Solver Pen) or the comparator (Loceryl, 5% amorolfine), respectively, for a period of 90 days. The primary objective of the investigation is the increase of percentage of healthy surface on the great toenail at study end versus baseline, as evaluated by a blinded investigator. Patients are followed up for a period of 90 days, with visits at D0 (baseline), D30, D60 and D90, respectively.

NCT ID: NCT04947358 Recruiting - Clinical trials for Longitudinal Observational Study With 6 Months Follow-up

Longitudinal Observational Study for mIddle Term Follow-up Patients Admitted for Acute Dyspnea in TunIsia

Start date: February 22, 2019
Study type: Observational

The purpose of the SIDI study is to follow, few months after discharge from the hospital, the patients admitted to the 3 emergency departments in Tunisia for acute dyspnea and to determine the proportion and the factors favoring rehospitalization and death.

NCT ID: NCT04924855 Recruiting - Clinical trials for Tunis Military Hospital Staff Vaccinated Against Covid 19

Immunity After COVID-19 Vaccination

Start date: July 2021
Study type: Observational [Patient Registry]

The purpose of the research is to evaluate kinetic after vaccination to the COVID-19 coronavirus by measurements of specific and neutralizant antibodies for spike antigenic sequences . This work will allow us to follow the efficacy and tolerance of the vaccine over a year, to evaluate the antibody profile, their kinetics, the fraction of neutralising antibodies and will also allow us to understand the attitudes to be taken to ensure the best protection for our staff

NCT ID: NCT04914767 Recruiting - SARS-CoV2 Infection Clinical Trials

Nigella 5 in the Treatment of SARS COV2 (COVID-19)

Start date: March 1, 2021
Phase: Phase 1
Study type: Interventional

The world is currently facing a crisis because of this potentially fatal situation of the COVID-19 epidemic without proven efficacy for any drug treatment, while the vaccination is not yet. This epidemic is caused by a new betacorona virus, now called SARS-CoV-2. The most common symptoms reported are fever, cough or chest tightness, and dyspnea. Most cases have a mild course

NCT ID: NCT04883203 Completed - Covid19 Clinical Trials

The Effect of Vitamin D Supplementation on COVID-19 Recovery

Start date: April 22, 2020
Phase: Phase 3
Study type: Interventional

The COVID-19 caused by SARS-CoV-2 has transmitted quickly as a global public health emergency. The median duration for Sars-CoV-2 carrying in COVID-19 patients was 20 days (IQR 16-28) What is the role of vitamin D supplementation on the recovery time of asymptomatic and pauci-symptomatic COVID-19 subjects? the intervention group will have vitamin D supplementation (200,000 IU / 1 ml of Cholecalciferol (1 ml) Oral form). Control group will have a placebo treatment (physiological saline). the negative RT-PCR date will be compared in the two groups

NCT ID: NCT04878887 Recruiting - Ultrasonography Clinical Trials

DRA vs PRA for US-guided Radial Artery Catheterization in ICU

Start date: March 26, 2021
Phase: N/A
Study type: Interventional

Patients were randomly divided into two groups: ultrasound-guided (US-guided) in-plane distal radial access (IP-DRA) and in-plane proximal radial access (IP-PRA) catheterization. For IP-DRA , a linear transducer is placed in the radial fossa, which is known as the snuff-box. After obtaining a long-axis view of the radial artery ,the needle is inserted in the midpoint of the small footprint transducer. Then,the needle is advanced under real-time US guidance until visualizing the tip of the needle inside the artery . For IP-PRA , a linear transducer is placed in the standard conventional forearm radial. After obtaining a long-axis view of the radial artery ,the needle is inserted in the midpoint of the small footprint transducer. Then,the needle is advanced under real-time US guidance until visualizing the tip of the needle inside the artery .