Cornea Clinical Trial
Official title:
MicroPulse Transscleral Laser Therapy and Its Short-term Impact on Ocular Surface
MicroPulse transscleral laser therapy (TLT) is proven to be effective in reducing intraocular pressure with minimal complications in either primary or secondary glaucoma. However, its impact on the human ocular surface remains unexplored. This study aims to bridge this gap by examining the clinical and histopathological effects of MicroPulse TLT on the ocular surface.
This prospective study, conducted at Mohamed Taher Maamouri University Hospital in Nabeul, Tunisia, investigates the clinical and histopathological short-term effects of MicroPulse transscleral laser therapy (TLT) on the ocular surface. The study involves 16 eyes from 15 adult patients. Participants underwent MicroPulse TLT, followed by conjunctival biopsies for the analysis of inflammation and fibrosis. Participants also benefited from ophthalmological examination and responded to the Ocular Surface Disease Index (OSDI) questionnaire before and after MicroPulse TLT. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT03674892 -
Intranasal Neurostimulation in Ameliorating Symptoms of Neuropathic Corneal Pain
|
N/A | |
| Recruiting |
NCT04439552 -
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
|
||
| Not yet recruiting |
NCT04122651 -
Toric Intraocular Lenses for Cataract Patients in the NHS
|
N/A | |
| Recruiting |
NCT03299530 -
Accuracy of Corneal Astigmatism in Different Region Modes
|
||
| Completed |
NCT04560790 -
Safety and Efficacy of CRISPR/Cas9 mRNA Instantaneous Gene Editing Therapy to Treat Refractory Viral Keratitis
|
N/A | |
| Recruiting |
NCT03010748 -
Multi-center Clinical Trial on Corneal Morphology Analysis in Chinese Population
|
||
| Completed |
NCT02293122 -
To Investigate Agreement Between the EM-3000 and the Predicate Device Noncon Robo Pachy (F&A) (CellChek XL)
|
||
| Completed |
NCT03906513 -
Evaluation of the Efficacy of OMK2 in Recovering Corneal Neural Damage in Patients With Diabetes
|
N/A | |
| Recruiting |
NCT05232539 -
Efficiency of Intraoperative Optical Coherence Tomography (iOCT)
|
N/A | |
| Completed |
NCT02781948 -
Evaluation of the Repeatability and Reproducibility of Corneal Epithelial Thickness Mapping With iVue SD-OCT
|
N/A | |
| Not yet recruiting |
NCT05345652 -
Evaluation Of Deep Anterior Lamellar Keratoplasty By Anterior Segment Ocular Coherence Tomography
|
||
| Completed |
NCT04804592 -
Investigation in Corneal Sensation and Contact Lens Wear
|
N/A | |
| Recruiting |
NCT04626583 -
Safety of Locally Delivered Allogeneic Mesenchymal Stromal Cells
|
Phase 1 | |
| Recruiting |
NCT04323358 -
Agreement and Accuracy of Different Devices for Biometry Measurements in Patients With Cataract
|
N/A | |
| Completed |
NCT06277349 -
Multifocal-toric IOL Compared to Multifocal IOL Combined With Limbal Relaxing Incisions for Correction of Moderate Astigmatism During Cataract Surgery
|
N/A | |
| Withdrawn |
NCT02395952 -
Healing of Persistent Epithelial Defects
|
N/A | |
| Completed |
NCT03518775 -
Repeatability and Reproducibility of the IOLMaster 700 Vers 1.70 and Agreement With IOLMaster 700 Vers. 1.50 and Pentacam
|
||
| Terminated |
NCT04969406 -
A Prospective Trial of the Intelon BOSS(TM) System
|
N/A | |
| Recruiting |
NCT05204329 -
Safety of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease
|
Early Phase 1 | |
| Completed |
NCT03127163 -
Intraestromal Corneal Ring in Mild Keratoconus
|
N/A |