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NCT ID: NCT03176238 Active, not recruiting - Clinical trials for Post Menopausal Breast Cancer

Study in Post-menopausal Women With Hormone Receptor Positive, HER2-negative Advanced Breast Cancer

Start date: March 29, 2013
Phase: Phase 3
Study type: Interventional

The present international, multi-center, open-label, single-arm study aims at collecting clinical safety, tolerability and efficacy data with the use of everolimus combined with exemestane in the Novartis Oncology Emerging Growth Market (EGM) countries for the treatment of post-menopausal women with hormone receptor (HR) positive, human epidermal growth factor receptor 2 (HER2) negative locally advanced or metastatic breast cancer after documented recurrence or progression following a non-steroidal aromatase inhibitor (NSAI) therapy.

NCT ID: NCT03164226 Recruiting - Clinical trials for Acute Coronary Syndrome

The Evaluation of Endothelial Function in the Diagnosis of Acute Coronary Syndrome (ACS)

Start date: May 15, 2015
Phase: N/A
Study type: Interventional

The objective of this study is to verify the contribution of digital plethysmography in the early diagnosis of acute coronary syndrome in emergency departments. To determine the sensitivity, specificity, negative and positive predictive value of this method that was not previously used for this purpose.

NCT ID: NCT03107585 Completed - Local Anesthesia Clinical Trials

Intermediate Cervical Block Under Ultrasound for Thyroid Surgery: Impact on Per and Postoperative Opioid Consumption

Start date: January 2015
Phase: N/A
Study type: Interventional

The investigators included prospectively 35 patients undergoing an intermediate cervical block under ultrasound (GP1) before a thyroidectomy ,compared to a group of 35 patients without a block (GP2).

NCT ID: NCT03105739 Completed - Clinical trials for Respiratory Complication

Timing of Withdrawal of the Laryngeal Mask Airway (LMA) in Children

Start date: October 5, 2016
Phase: N/A
Study type: Interventional

The purpose of this prospective, randomized study was to compare the incidence of adverse events associated with removal of the LMA either in deeply anesthetised or awake patients.

NCT ID: NCT03085576 Recruiting - Atrial Fibrillation Clinical Trials

NATional TUnisian REgistry of Atrial Fibrillation

Start date: March 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

A non-interventional, national longitudinal study of atrial fibrillation performed with 186 cardiologists.

NCT ID: NCT03075566 Recruiting - Clinical trials for Coronary Artery Disease

Coronary Artery Disease: a Case- Control Study

Start date: September 2014
Phase: N/A
Study type: Observational

Atherosclerosis is a chronic inflammatory condition, which is associated by the involvement of several pathological events, and alteration in the serum levels of pro- and anti-inflammatory, and lipid markers. The investigators evaluated the contribution of serum biomarkers levels to the pathogenesis of coronary artery disease, namely their association with risk factors, clinical presentation, extent and severity of atherosclerotic changes accompanying coronary artery disease.

NCT ID: NCT03072329 Completed - Penile Surgery Clinical Trials

Neurostimulation in Pudendal Nerve Block

Start date: October 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to check whether the success rate of blind pudendal nerve block in penile surgery can be optimized by the search for a motor response during neurostimulation.

NCT ID: NCT03017248 Active, not recruiting - Pain Clinical Trials

Low-dose Ketamine for Acute Pain in the Emergency Department

Start date: January 2016
Phase: Phase 1
Study type: Interventional

This study aims to determine the efficacy and safety of low dose ketamine in association with IV morphine in the management of acute moderate to severe pain in emergency department. The investigators hypothesize that low dose ketamine will result in more effective pain control than morphine alone and will not be associated with an increase in adverse events.

NCT ID: NCT02978690 Recruiting - Psoriasis Clinical Trials

BI655130 Single Dose in Generalized Pustular Psoriasis

Start date: December 19, 2016
Phase: Phase 1
Study type: Interventional

This is a phase I, open label, single group study that is being performed to assess the safety, tolerability, Pharmacokinetics (PK) , Pharmacogenomics (PGx) and efficacy of a single dose of BI 655130 in adult patients with active Generalized Pustular Psoriasis (GPP).

NCT ID: NCT02963454 Recruiting - Septic Shock Clinical Trials

Effects of Levosimendan on Cellular Metabolic Alterations in Patients With Septic Shock

Start date: January 2011
Phase: N/A
Study type: Interventional

To investigate changes in the concentration of glucose, lactate, pyruvate and glycerol in the extracellular fluid of the skeletal muscle following levosimendan administration in patients with septic shock.