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NCT ID: NCT06357897 Not yet recruiting - Clinical trials for Functional Constipation

The Efficacy and Palatability of Developed Polyethylene Glycol-based Formula for Children With Functional Constipation

Start date: May 2024
Phase: N/A
Study type: Interventional

This study aims to evaluate the efficacy and palatability of a developed polyethylene glycol-based formula compared with the standard polyethylene glycol (PEG) in the treatment of children with functional constipation for 8 weeks. Besides, we also aim to assess the side effects of a developed PEG-based formula as well as evaluate the change of rectal diameter from baseline at each visit between 2 groups.

NCT ID: NCT06356129 Recruiting - Clinical trials for Large B-cell Lymphoma

Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma

GOLSEEK-1
Start date: June 24, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effectiveness and safety of golcadomide in combination with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy vs placebo in combination with R-CHOP chemotherapy in participants with previously untreated high-risk large B-cell lymphoma (LBCL).

NCT ID: NCT06353165 Completed - Plaque, Dental Clinical Trials

Anti-bacterial Clinical Study on Teeth, Tongue, Cheek, Gum, and Saliva

Start date: March 8, 2023
Phase: Phase 3
Study type: Interventional

This 4-week clinical study was designed to examine the antibacterial efficacy of brushing with a 0.454% stannous fluoride toothpaste with potassium nitrate and pyrophosphate compared to a toothpaste containing 0.76% MFP (marketed as Colgate Cavity Protection Toothpaste) in different regions of the mouth (dental plaque, tongue, cheek, gum surface and in saliva) 12 hours post-brushing (overnight) after 2 and 4 weeks of product use.

NCT ID: NCT06346392 Recruiting - Gastric Cancer Clinical Trials

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

Start date: March 4, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this study is to measure the efficacy and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma expressing CLDN18.2.

NCT ID: NCT06345586 Not yet recruiting - Contraception Clinical Trials

Drospirenone Only Pills and Cervical Mucus Changes: A Pre- and Post-Bariatric Surgery Study

Start date: April 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to study the effect of Drospirenone on cervical mucus change by modified Insler score, pre-bariatric surgery and post-bariatric surgery

NCT ID: NCT06345560 Not yet recruiting - Contraception Clinical Trials

Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery Study

Start date: April 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate whether bariatric surgery affects Drospirenone only pills absorption

NCT ID: NCT06344637 Active, not recruiting - Pain, Procedural Clinical Trials

Effects of Cervical Lidocaine Spray on Pain Relief During Manual Vacuum Aspiration

Start date: December 14, 2023
Phase: N/A
Study type: Interventional

This randomized control trial aim to evaluate the effectiveness of local lidocaine spray application to the cervix on the reducing of pain score during the manual vacuum aspiration

NCT ID: NCT06340464 Recruiting - Cardiac Surgery Clinical Trials

Preoperative Nutritional Status Scores to Predict PPC in Elderly With Cardiac Surgery

Start date: March 21, 2024
Phase:
Study type: Observational [Patient Registry]

This prospective study investigate prognostic values and compare the role of nutritional status by using GNRI, MNA, and PNI in predicting post-operative pulmonary complication among elderly patients with cardiac surgery.

NCT ID: NCT06339151 Recruiting - Pain, Postoperative Clinical Trials

Comparing Single Dose and Multiple Dose of Dexamethasone Post TKA

Start date: March 23, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate the efficacy of single dose and double dose of dexamethasone after primary total knee replacement. The main question[s] it aims to answer [is/are]: Does 24 hours-interval of double dose of dexamethasone have better analgesic effect than single dose and 12 hours interval of double dose of dexamethasone after primary total joint replacement? Researchers will compare double dose of dexamethasone group to see if [insert effects]. Participants will [describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items].

NCT ID: NCT06338696 Not yet recruiting - Clinical trials for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Thailand ATTR-CM Registry

Start date: June 1, 2024
Phase:
Study type: Observational [Patient Registry]

The investigators of this registry aim to study the natural history, clinical presentation, characteristics, and imaging findings of patients diagnosed with ATTR amyloidosis in Thailand longitudinally. This will enable the investigators to study this disease in depth. With a better understanding, the investigators can aim to develop early screening programs for at-risk patients, raising awareness among non-cardiologists. As amyloid-specific therapies have now become available in Thailand, the findings of this registry can be helpful for epidemiological studies in Thailand.