Clinical Trials Logo

Filter by:
NCT ID: NCT02720094 Active, not recruiting - HIV Infections Clinical Trials

Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men

Start date: December 2016
Phase: Phase 2/Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of the injectable drug cabotegravir (CAB LA), for pre-exposure prophylaxis (PrEP) in HIV-uninfected cisgender men and transgender women who have sex with men (MSM and TGW).

NCT ID: NCT02645760 Active, not recruiting - Low Back Pain Clinical Trials

Effectiveness of Core Stabilization Exercise in Patients With Subacute Non-Specific Low Back Pain

CSENSLBP
Start date: October 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to examines the effectiveness of Core stabilization exercise on pain intensity at rest, functional disability, lumbar movement and ability to perform repositioning tasks (joint position sense) in patients with subacute non-specific low back pain.

NCT ID: NCT02633943 Active, not recruiting - Clinical trials for Transfusion-dependent Beta-Thalassemia

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

Start date: January 2014
Phase:
Study type: Observational

This is a multi-center, long-term safety and efficacy follow-up study for subjects with transfusion-dependent β-thalassemia (TDT) who have been treated with ex vivo gene therapy drug product in bluebird bio-sponsored parent clinical studies. After completing the parent clinical study (approximately 2 years), eligible subjects will be followed for an additional 13 years for a total of 15 years post-drug product infusion. No investigational drug product will be administered in this study.

NCT ID: NCT02615691 Active, not recruiting - Hemophilia A Clinical Trials

A Study of PEGylated Recombinant Factor VIII (BAX855) in Previously Untreated Young Children With Severe Hemophilia A

Start date: November 12, 2015
Phase: Phase 3
Study type: Interventional

This study is for young children with severe hemophilia A who have previously not been treated with BAX855 or other FVIII concentrates. The main aim of the study is to check for side effects from treatment with BAX855. This includes the buildup of antibodies against FVIII which may stop BAX855 from working properly. Another aim is to learn how well BAX855 controls bleeding. In this study, the children can receive BAX855 either as preventative treatment (prophylaxis), or as needed to treat bleeding (on-demand). In case a participant develops antibodies, treatment will be provided as part of the study.

NCT ID: NCT02544958 Active, not recruiting - Enlarged Pores Clinical Trials

Er:YAG Laser for Treatment of Enlarged Pores

Start date: May 2015
Phase: N/A
Study type: Interventional

To investigate the efficacy of Erbium:Yttrium aluminum garnet laser (Er:YAG) in the treatment of enlarged pores.

NCT ID: NCT02511106 Active, not recruiting - Clinical trials for Stage IB-IIIA Non-small Cell Lung Carcinoma

AZD9291 Versus Placebo in Patients With Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy.

ADAURA
Start date: October 21, 2015
Phase: Phase 3
Study type: Interventional

To assess the efficacy and safety of AZD9291 versus Placebo, in patients with Epidermal Growth Factor Receptor Mutation Positive stage IB-IIIA non-small cell lung carcinoma, following complete tumour resection with or without adjuvant chemotherapy

NCT ID: NCT02494986 Active, not recruiting - Clinical trials for Human Immunodeficiency Virus Type 1

A Roll-over Study With Rilpivirine for Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants Who Participated in Rilpivirine Pediatric Studies

Start date: July 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to provide continued access to rilpivirine (RPV) for participants who were treated with RPV in a clinical development pediatric study with rilpivirine and who, at the time of roll-over, experience and are expected to continue experiencing clinical benefit from RPV treatment.

NCT ID: NCT02466620 Active, not recruiting - Body Weight Clinical Trials

A Comparison of Paediatric Weight Estimation Methods for Emergency Resuscitation

Start date: February 2015
Phase: N/A
Study type: Observational

The purpose of this study is to study the validity, reliability and practicality of the different weight estimation methods (parent estimation method, Mercy method, Broselow tape, original and update APLS) in Thai children.

NCT ID: NCT02455622 Active, not recruiting - Hunter Syndrome Clinical Trials

Long-term Evaluation on Height and Weight in Patients With MPS II Who Started Treatment at < 6 Years of Age

Start date: October 28, 2015
Phase: Phase 4
Study type: Interventional

This long-term study will provide Elaprase treatment to children enrolled in this study and will utilize data from both enrolled patients and Hunter Outcome Survey (HOS) patient registry data to conduct the primary growth analysis to assess changes in height and weight in patients with Mucopolysaccharidosis II (Hunter syndrome) MPS II.

NCT ID: NCT02453282 Active, not recruiting - Clinical trials for Non-Small-Cell Lung Carcinoma NSCLC

Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC)

MYSTIC
Start date: July 21, 2015
Phase: Phase 3
Study type: Interventional

This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of MEDI4736 + tremelimumab combination therapy and MEDI4736 monotherapy versus platinum-based SoC chemotherapy in the first-line treatment of patients with epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) wild-type locally advanced or metastatic NSCLC