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NCT ID: NCT05203900 Recruiting - Clinical trials for Low Birth Weight Infants

The Influence by Dietary Human Milk Oligosaccharide in Low Birth Weight Infants

Start date: December 13, 2021
Phase: N/A
Study type: Interventional

This study aims to investigate the concentration of various growth factors and cytokines in blood, and to examine the gut microbiota of low birth weight infants fed with formulas with or without Human Milk Oligosaccharide (HMO) supplement. Eligible low birth weight infants are allocated to two groups, Investigational formula (with HMO) or Control formula (without HMO). The subjects are taking the assigned formula when they need to be supplemented with formula. After the informed consent was obtained and eligibility was confirmed, the intervention period begins, and ends at the one-month-old medical check-up with the assessment of the various blood growth factors and cytokines, and the gut microbiota.

NCT ID: NCT05201794 Not yet recruiting - Dengue Clinical Trials

A Study of JNJ-64281802 for the Prevention of Dengue Infection

Start date: July 29, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the prophylactic effect of JNJ-64281802 with respect to the prevention of laboratory-confirmed dengue virus (DENV) infection up to last day of dosing among participants who have no evidence of current DENV infection at baseline.

NCT ID: NCT05197712 Not yet recruiting - COVID-19 Vaccine Clinical Trials

A Phase 1, Open-label Study to Evaluate the Safety, Tolerability, and Reactogenicity of the Baiya SARS-CoV-2 Vax 2 Vaccine in Healthy Adults

Start date: February 2022
Phase: Phase 1
Study type: Interventional

The investigational product Baiya SARS-CoV-2 Vax 2 vaccine is a second-generation of protein subunit vaccine from plant. The primary objective aiming to evaluate the safety, tolerability, and reactogenicity of Baiya SARS-CoV-2 Vax 2 in adults (aged between 18 to 64 years, inclusive) after 2 doses of Baiya SARS-CoV-2 Vax 2 given 21 days apart IM, up to 28 days after the second vaccination. The secondary objective aiming to evaluate long-term safety profile (up to 1 year) and evaluate immunogenicity after 2 doses of Baiya SARS-CoV-2 Vax 2 given 21 days apart.

NCT ID: NCT05195346 Recruiting - HIV Clinical Trials

Undetectable = Untransmissible in Thailand (888/64)

888/64
Start date: December 1, 2021
Phase:
Study type: Observational

This is a cross-sectional study to assess awareness, knowledge, and implementation of the concept of U=U among Thai PLHIV and Thai HIV healthcare providers, as well as associated factors. Data will be collected on an online survey platform called Alchemer. Questions on the survey will evaluate awareness, knowledge, and implementation of U=U among participants, as well as collect sociodemographic information of participants.

NCT ID: NCT05183711 Completed - Clinical trials for Anesthesia Competences (Self-evaluation)

Self-Evaluating Anesthesia Competency Among Nurse Anesthetists

Start date: October 1, 2019
Phase:
Study type: Observational

Continuing Medical Education (CME) has been proved that not only improving healthcare provider performance but also improving the patient outcome.Previous studies results showed that long established and multiple CME sessions, various methods and interactive sessions help the learners to improve their competency. CME among the nurses seem to be more difficult than in the physicians. Regarding to work schedule, lack of support from institution especially funding. Outcome-based continuing professional development course that provide practical skills sessions and give a chance for learners to reflect themselves help the learner to determine the performance gap between the learner real life practice and the standard of care. So in term of professional development, the practitioner can improve their competency from clinical level to professional level and finally managerial level. After graduation,There are just only few anesthesia education courses for nurse anesthetists in each year. These may be not enough in order to maintain either knowledge or essential skills needed in anesthesia real life practice. The primary objective of this is to determine that which kinds of knowledge and skills in anesthesia that the nurse anesthetists in our institution lack off.

NCT ID: NCT05183061 Completed - Clinical trials for The iNPH Patients Scheduled for VP or LP Shunt Procedures

Factors Associated With Post-induction Hypotension in iNPH Patient Undergoing VP and LP Shunt

Start date: June 1, 2021
Phase:
Study type: Observational

This study is a retrospective work involving the review of patients who were scheduled for VP or LP shunt in Siriraj Hospital, Mahidol University, Thailand. The sample size calculation was based on the rule of thumbs of the logistic regression comprising 18 risk factors. The incidence of post-induction hypotension according to our institution's pilot study November 2019-January 2020) was 47%. With 10% addition for missing data and other possible reasons, the sample size was 426. The primary objective of the study is to report the factors associated with post-induction hypotension in iNPH patients undergoing VP or LP shunt procedures. Our secondary objective is to determine the incidence of post-induction hypotension in these patients.

NCT ID: NCT05171647 Not yet recruiting - Clinical trials for Non-Hodgkin Lymphoma

A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

SUNMO
Start date: March 31, 2022
Phase: Phase 3
Study type: Interventional

This study will assess the efficacy and safety of mosunetuzumab in combination with polatuzumab vedotin (M+P) in participants with relapsed or refractory (R/R) diffuse-large B-cell lymphoma (DLBCL), transformed follicular lymphoma (trFL) and FL Grade 3B (FL3B) in comparison with a commonly used regimen in this participant population, rituximab, gemcitabine and oxaliplatin (R-GemOx).

NCT ID: NCT05168137 Recruiting - HIV Infections Clinical Trials

Efficacy and Safety of Low-Dose Colchicine on Surrogate Markers of Cardiovascular Events in People Living With HIV Receiving Antiretroviral Therapy

Start date: February 1, 2020
Phase: Phase 4
Study type: Interventional

In a double-blind, randomized controlled trial, we assigned PLWH receiving ART without a history of cardiovascular events to received colchicine 0.6 mg once daily or placebo. The primary endpoint was the mean difference of hs-CRP, IL-6, and IL-1 Ra levels at three and six months. The secondary endpoint was to access safety outcomes.

NCT ID: NCT05166122 Not yet recruiting - Clinical trials for Diabetic Retinopathy

Implementation of an Integrated System of Artificial Intelligence and Referral Tracking for Real-time Diabetic Retinopathy Screening

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This research study aims to bring an artificial intelligence system to screen for diabetic retinopathy (DR) along with referral tracking systems to the screening unit in Uthai Hospital in Phra Nakhon Sri Ayutthaya to assess the effectiveness of screening and follow-up of patients referred to Phra Nakhon Sri Ayutthaya Hospital. It will be compared with the existing screening system and follow up with regular referral by personnel

NCT ID: NCT05165563 Completed - Dental Implant Clinical Trials

Treatment Time Comparing Digital & Conventional Workflows

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

This randomized controlled trial (RCT) analyzed monolithic single-unit implant restorations out of lithium disilicate (LS2) or polymer-infiltrated ceramic networks (PICN) in a chairside digital workflow (Test) and a conventional protocol (Control). The primary outcome was to investigate the treatment time of the overall operation. The null hypothesis of this RCT was that both workflows had comparable results with respect to the defined outcomes.