Clinical Trials Logo

Filter by:
NCT ID: NCT06279156 Completed - Clinical trials for Intradialytic Hypotension

Optimal Frequency of Total Body Water Measurements by Bioelectrical Impedance Analysis to Prevent Intradialytic Hypotension

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the efficiencies of bioelectrical impedance analysis (BIA) measurement frequency in preventing intradialytic hypotension in end-stage renal disease (ESRD) patients undergoing regular hemodialysis. The main question it aims to answer is the optimum frequency of BIA measurements to prevent intradialytic hypotension. Participants will undergo BIA measurements to determine their appropriate dry weight, and factors affecting intradialytic hypotension. Researchers will compare the efficiencies of bioelectrical impedance analysis (BIA) measurements between the every-1-month group and the every-2-month group to prevent intradialytic hypotension.

NCT ID: NCT06277882 Not yet recruiting - Cirrhosis Clinical Trials

Efficacy and Durability of Hepatitis A Vaccination in Patients With Advanced Fibrosis and Cirrhosis

Start date: March 1, 2024
Phase: Phase 4
Study type: Interventional

The hepatitis A virus (HAV) is a significant global public health concern. The hepatitis A virus is transmitted primarily by the faecal-oral route, leading to acute hepatitis. Symptoms include low-grade fever, anorexia, jaundice, and typically resolve without complications. However, HAV infection in patients with chronic liver disease, especially those over 50 years old, may result in more severe outcomes, including fulminant hepatitis, with a higher mortality rate compared to the general population HAV vaccination is a cornerstone of prevention, especially in high-risk groups. Currently, there is a recommendation to vaccinate patients with chronic liver disease against HAV infection. However, these patients often have compromised immune responses, leading to lower vaccine efficacy compared to the general population. The goal of this randomized controlled trial is to compare the efficacy and safety of the standard 2-dose (0, 6 months) hepatitis A vaccination regimen with an intensive 3-dose (0, 1, 6 months) schedule in patients with advanced fibrosis and cirrhosis. The main questions it aims to answer are: - Compared the seroconversion rate of the standard 2-dose (0, 6 months) hepatitis A vaccination regimen versus the intensive 3-dose (0, 1, 6 months) hepatitis A vaccination regimen in patients with advanced fibrosis and cirrhosis. - Compared the antibody levels against the hepatitis A virus (Anti-HAV IgG) of the standard 2-dose (0, 6 months) hepatitis A vaccination regimen versus the intensive 3-dose (0, 1, 6 months) hepatitis A vaccination regimen in patients with advanced fibrosis and cirrhosis.

NCT ID: NCT06277635 Recruiting - Clinical trials for Rheumatoid Arthritis

Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic Diseases

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

To study the effect of silymarin against methotrexate-induced liver injury in rheumatic diseases including rheumatoid arthritis, psoriatric arthritis and psoriasis

NCT ID: NCT06276218 Recruiting - Clavicle Fracture Clinical Trials

Efficacy of Self - Adjustable Clavicular Brace Versus Standard Clavicular Brace for Treatment of Mid Shaft Clavicle Fracture: A Randomized Controlled Study

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

A randomized control trial was conducted to compare the outcomes of conservative management for closed midshaft clavicular fractures using self-adjustable clavicular brace and standard clavicular brace.

NCT ID: NCT06275828 Active, not recruiting - Clinical trials for Anterior Cruciate Ligament Tear

The Effect of Perioperative and Postoperative Music Reduces Pain Perception After Anterior Cruciate Ligament Reconstruction

Start date: December 15, 2022
Phase: N/A
Study type: Interventional

study the effect of music therapy in pre-operative and post operative period and measure the out come by the visual analog scale (pain score) and analgesic drug use such as morphine and the anxiety score

NCT ID: NCT06274242 Active, not recruiting - Constipation Clinical Trials

Mixed Natural Prebiotic-Fibers Impact on Stool Frequency and Fecal Microbiota in Constipated Thai Adults

Start date: March 10, 2023
Phase: N/A
Study type: Interventional

Mixed Natural Prebiotic-Fibers Impact on Stool Frequency and Fecal Microbiota in Constipated Thai Adults: A Randomized Clinical Trial.

NCT ID: NCT06273384 Not yet recruiting - Clinical trials for Helicobacter Pylori Infection

Diagnostic Performance of CIM for Helicobacter Pylori Infection in Patients With Peptic Ulcer Bleeding

CIM
Start date: March 1, 2024
Phase:
Study type: Observational

The goal of this cross-sectional study is to evaluate the efficacy of current infection marker (CIM) method for H. pylori detection. The main questions it aims to answer are: - To evaluate the efficacy of CIM method for H. pylori detection compared to rapid urease test(RUT), histopathology, polymerase chain reaction (PCR), and urea breath test (UBT) in patients who presented with upper gastrointestinal hemorrhage from peptic ulcer, and their sensitivity, specificity, accuracy, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio, and negative likelihood ratio. - To evaluate the advantages of CIM method for H. pylori detection comparing to RUT, histopathology, PCR, and UBT in patients who presented with upper gastrointestinal hemorrhage from peptic ulcer as net reclassification index (NRI). - To study the associated factors in false negative value of H. pylori detection methods with CIM, RUT, histopathology, PCR, and UBT.

NCT ID: NCT06273254 Not yet recruiting - Clinical trials for Bioequivalence Study

A Bioequivalence Study of Sacubitril/Valsartan Film-coated Tablets Under Fasting Conditions

Start date: April 2024
Phase: Phase 1
Study type: Interventional

Primary objective is to is to evaluate the bioequivalence of two formulations

NCT ID: NCT06272019 Recruiting - Clinical trials for The Retention of Iodine in Saliva Over the Time

Alternative Application Methods of Pre-procedural Povidone Iodine Mouthrinse

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

To compare the iodine remaining in saliva between gargle method and swab method

NCT ID: NCT06270849 Completed - Clinical trials for Validity of Thai Version of the ICIQ-FLUTS LF Questionnaire

Validity and Reliability of ICIQ-FLUTS LF in Thai Version and Correlation With IPSS

Start date: February 24, 2023
Phase:
Study type: Observational

The investigators recruited participants, who were female with LUTS 50 participants for known group validity and 80 normal control females to evaluate for construct validity and test for reliability by statistical analysis.