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NCT ID: NCT00293124 Completed - Clinical trials for Gastrointestinal Stromal Tumors

Open-label Trial of GlivecWith Unresectable or Metastatic Malignant Gastrointestinal Stromal Tumors

Start date: March 2004
Phase: Phase 3
Study type: Interventional

The rationale is to assess the clinical and biological activity of Imatinib and to compare the data with historic data. Additionally this study has been designed to gain more experience with the treatment of GIST in several Central and Eastern European Countries.

NCT ID: NCT00292552 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Evaluation of COPD (Chronic Obstructive Pulmonary Disease) to Longitudinally Identify Predictive Surrogate Endpoints

ECLIPSE
Start date: December 2005
Phase: N/A
Study type: Observational

This is a 3 year longitudinal study to identify novel endpoints and compare these with standard measures such as forced expiratory volume in 1 second (FEV1) for their ability to measure and predict COPD (Chronic Obstructive Pulmonary Disease) severity and its progression over time. Control subjects (smokers and never smokers) will be recruited as comparators with the COPD subjects.

NCT ID: NCT00288249 Completed - Breast Neoplasms Clinical Trials

Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Breast Cancer

Start date: December 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether the study drug is effective and safe in the treatment of patients with metastatic breast cancer

NCT ID: NCT00286130 Completed - Clinical trials for Metastatic Colorectal Cancer

Safety and Efficacy of Folfox6 + Cetuximab Versus Folfiri +Cetuximab in Patients With Metastatic Colorectal Cancer

Start date: July 2005
Phase: Phase 2
Study type: Interventional

In Patients with metastatic colorectal cancer the following treatments first-line Folfiri+Cetuximab first-line Folfox6 + Cetuximab will be concerning efficacy and safety. The trial compares Folfiri + Cetuximab and Folfox6 + Cetuximab concerning efficacy and safety as first

NCT ID: NCT00274690 Completed - Clinical trials for Postoperative Nausea and Vomiting

Post-Operative Nausea And Vomiting Study In Female Patients

Start date: February 2005
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to determine an effective dose of this NK-1 anti-emetic medication to prevent nausea and vomiting in females after surgery.

NCT ID: NCT00273481 Completed - Ocular Hypertension Clinical Trials

Cosopt Versus Xalacom

Start date: September 2005
Phase: Phase 4
Study type: Interventional

To compare the intraocular pressure efficacy and safety of the DTFC given twice daily versus the LTFC given once every morning following a run-in period with timolol maleate given twice daily.

NCT ID: NCT00271180 Recruiting - Heart Failure Clinical Trials

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

PPR
Start date: January 1983
Phase:
Study type: Observational

The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival probabilities.

NCT ID: NCT00261495 Completed - Pain Clinical Trials

A Study of the Effectiveness and Safety of Sustained-release Hydromorphone (a Strong Opioid) in Patients With Chronic Noncancer Pain.

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effectiveness and safety of sustained- release hydromorphone, formulated to release slowly over time, taken once daily, and controlled- release oxycodone taken twice daily, in patients with chronic non-cancer pain. The study will also determine the dose of sustained-release hydromorphone that provides a level of pain control that is equal to the pain control provided by control-released oxycodone (equi-analgesic dosage).

NCT ID: NCT00252824 Completed - Asthma Clinical Trials

STYLE - Symbicort Single Inhaler Therapy vs Conventional Therapy in Treatment of Persistent Asthma

Start date: July 2005
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare the efficacy of a flexible dose of Symbicort with conventional stepwise treatment according to asthma treatment guidelines in patients with persistent asthma

NCT ID: NCT00245739 Approved for marketing - HIV Infections Clinical Trials

TMC114-C226: An Early Access Program to Evaluate the Long-term Safety and Tolerability of TMC114 Combined With a Low Dose of Ritonavir (TMC114/r) With Other Antiretrovirals, for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens.

Start date: n/a
Phase: Phase 3
Study type: Expanded Access

The purpose of this study is to provide early access to TMC114 (a protease inhibitor) for HIV-1 infected patients with limited or no treatment options, who have failed multiple antiretroviral (ARV) regimens, and to evaluate the longer-term safety and tolerability of TMC114/r in combination with other antiretrovirals