Clinical Trials Logo

Filter by:
NCT ID: NCT03466957 Recruiting - Cancer Clinical Trials

Individual Approach in Gynecological Cancer Brachytherapy

Start date: May 2016
Phase: N/A
Study type: Interventional

MRI guided adaptive brachytherapy (BT) represents the gold standard in the treatment of gynecological cancers. Commercially available standard MRI compatible applicators for BT of gynecological cancers don't always allow for optimal target volume coverage. Three-dimensional (3D) printed technology enables versatile possibilities of improvement of standard applicators and development of novel applicators with better coverage of the target volume. The purpose of this study is to implement and assess 3D printing technology as an instrument for designing and manufacturing applicators for individualized BT of gynecological cancers.

NCT ID: NCT03466411 Not yet recruiting - Crohn's Disease Clinical Trials

A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

Start date: April 1, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this program is to evaluate the efficacy and safety of guselkumab in participants with Crohn's disease.

NCT ID: NCT03445000 Not yet recruiting - Clinical trials for Non-small Cell Lung Cancer

ALEctinib for the Treatment of Pretreated RET-rearranged Advanced Non-small Cell Lung Cancer Treatment of Pretreated RET-rearranged Advanced NSCLC

Start date: March 2018
Phase: Phase 2
Study type: Interventional

A research study to evaluate the activity of alectinib for the Treatment of pretreated patients with advanced NSCLC that have confirmed RETrearrangement.

NCT ID: NCT03440125 Completed - Low Back Pain Clinical Trials

Cayenne Pepper Cataplasm - Safety Study

Start date: March 15, 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The beneficial analgesic effects of Rubefacenciae (redden skin substances), is known since 1830 as a treatment for pain, cramps, and disorders of the musculoskeletal system. Herbal cataplasms containing rubefacient substances, such as Cayenne pepper, are commonly used as natural medications to treat painful or aching areas in the case of acute or chronic back pain, and rheumatisms. In Vienna and lower Austria, a Cayenne Pepper Cataplasm (CPC) application containing Cayenne pepper and Kaolin powder in mixed proportion, is commonly used to treat musculoskeletal conditions of pain especially of the low back. However, a concern about the safety of such applications was recently raised. Therefore, the aims of the present study are to evaluate the effects of 10x 20min CP cataplasm application as a single treatment or in combination with electrical stimulation and massage on selected functional and molecular parameters on i) healthy subjects and ii) subjects suffering from low back pain.

NCT ID: NCT03432130 Enrolling by invitation - Body Composition Clinical Trials

Injury Occurrence in Hip-hop Dance

Start date: September 30, 2017
Phase: N/A
Study type: Interventional

The study will investigate the effect of structural training program and body composition on injury occurrence in hip-hop dance. Assuming that training program can significantly lower the number of injuries (experimental group will have less injuries during and at the end of the trial) and that body fat percentage negatively effects injury occurrence (dancers with higher body fat percentage will be more often injured).

NCT ID: NCT03421834 Recruiting - Clinical trials for Ventricular Tachycardia

Impact of PREVENTIVE Substrate Ablation of Coronary Chronic Total Occlusion on Implantable cardioVerTer-Defibrillator Interventions

Start date: February 6, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to assess whether preventive substrate ablation of chronic total occlusion infarct-related artery (CTO-IRA) area in heart failure (HF) patients correlates with lower appropriate implantable cardiac defibrillator (ICD) therapies. In addition, the purpose of the study is to determine whether prophylactic substrate ablation at the time of primary ICD implantation in high-risk ischemic patients affects unplanned hospitalization, HF progression, and quality of life.

NCT ID: NCT03415464 Active, not recruiting - Low Back Pain Clinical Trials

Prevention of Musculoskeletal Injuries in Slovenian Armed Forces

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Physical readiness of military personnel is a corner stone of each army, as soldiers are expected to meet high physical demands on a daily basis and soldiers have mandatory one hour of physical conditioning each day. Participation in physical conditioning rises the risk for musculoskeletal injuries, and our 10-year retrospective analysis shows that each year 5% of soldiers sustain a sports injury during physical conditioning and that ankle and knee injuries have highest incidence rate of 25% and 20%, respectively. The primary aim of our study is to lower the rate of ankle and knee injuries through implementation of preventive exercise program. The study is designed as a prospective randomized controlled trial with two arms (experimental and control).

NCT ID: NCT03411512 Completed - Clinical trials for Heart Defects, Congenital

Congenital Heart Defects and NIRS

Start date: December 1, 2012
Phase: N/A
Study type: Observational

Congenital Heart Defects and NIRS

NCT ID: NCT03402841 Recruiting - Clinical trials for Non-Germline BRCA Mutated Ovarian Cancer

Multicentre Study of Olaparib Maintenance Monotherapy in Platinum Sensitive Relapsed Non gBRCAm Ovarian Cancer Patients

Start date: January 30, 2018
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the efficacy and safety of single-agent olaparib as a maintenance treatment in patients with relapsed High Grade Serous Ovarian Cancer (including patients with primary peritoneal and/or fallopian tube cancer) or high grade endometrioid cancer who do not have known deleterious or suspected deleterious germline BRCA mutations (non-gBRCAm) and who had responded following platinum based chemotherapy.

NCT ID: NCT03399240 Completed - No Conditions Clinical Trials

Clinical Evaluation of the Accuracy of Vitastiq Device for Tracking Vitamin and Mineral Trend in Human Body

Start date: May 17, 2017
Phase: N/A
Study type: Interventional

This is a single site evaluation study of Vitastiq device accuracy in healthy men and women in ratio 1:1 (approximately) aged between 18 and 64 years. A total of 45 Vitastiq personal devices will be used by volunteers for two months. The Vitastiq device will be evaluated during three site visits: on day 1, 29 ± 4 days and 57 ± 4 days. During site visit days, blood sampling will be collected and analysed and readings using Vitastiq device will be performed. Data will be analysed retrospectively to evaluate Vitastiq performance compared to blood tests results.