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NCT ID: NCT05780463 Completed - COVID-19 Clinical Trials

MP0420 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

Start date: June 11, 2021
Phase: Phase 3
Study type: Interventional

This study looks at the safety and effectiveness of MP0420 in treating COVID-19 in people who have been hospitalized with the infection. Participants in the study will be treated with either MP0420 plus current standard of care (SOC), or with placebo plus current SOC. This is ACTIV-3/TICO Treatment Trial H5.

NCT ID: NCT05780424 Completed - COVID-19 Clinical Trials

BRII-196/BRII-198 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

Start date: December 16, 2020
Phase: Phase 3
Study type: Interventional

This study looks at the safety and effectiveness of BRII-196/BRII-198 in treating COVID-19 in people who have been hospitalized with the infection. Participants in the study will be treated with either BRII-196/BRII-198 plus current standard of care (SOC), or with placebo plus current SOC. This is ACTIV-3/TICO Treatment Trial H3.

NCT ID: NCT05780281 Completed - COVID-19 Clinical Trials

VIR-7831 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

Start date: December 16, 2020
Phase: Phase 3
Study type: Interventional

This study looks at the safety and effectiveness of VIR-7831 in treating COVID-19 in people who have been hospitalized with the infection. Participants in the study will be treated with either VIR-7831 plus current standard of care (SOC), or with placebo plus current SOC. This is ACTIV-3/TICO Treatment Trial H2.

NCT ID: NCT05780268 Completed - COVID-19 Clinical Trials

LY3819253 (LY-CoV555) for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

Start date: August 5, 2020
Phase: Phase 3
Study type: Interventional

This study looks at the safety and effectiveness of LY3819253 in treating COVID-19 in people who have been hospitalized with the infection. Participants in the study will be treated with either LY3819253 plus current standard of care (SOC), or with placebo plus current SOC. This is ACTIV-3/TICO Treatment Trial H1.

NCT ID: NCT05779072 Completed - Myopia Clinical Trials

Dual Focus Soft Contact Lens Wear Cessation Study

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of ceasing treatment with dual focus soft contact lenses.

NCT ID: NCT05756478 Completed - Polypharmacy Clinical Trials

Appropriate Prescribing for Older Adults With Multimorbidity (Pro-M)

Pro-M
Start date: February 1, 2023
Phase: N/A
Study type: Interventional

This is a two-site feasibility study to test implementation of an intervention that aims to reduce inappropriate prescribing for older adults with multimorbidity in geriatric medicine specialist clinics at public hospitals in Singapore. The specific aims are: 1. To assess the implementation outcomes: Appropriateness, Penetration/Reach, Acceptability, Feasibility, Sustainability (primary) 2. To collect data on recruitment and pre-post data on prevalence of potentially inappropriate prescribing (PIP) for the purpose of determining sample size for a scale up next phase study (secondary). 3. To conduct cost analysis of the intervention (secondary).

NCT ID: NCT05692869 Completed - Healthy Clinical Trials

A Study of Continuous Blood Pressure Monitoring in Healthy Participants

Start date: January 31, 2023
Phase: N/A
Study type: Interventional

The main purpose of this study in healthy participants is to find out whether the traditional ambulatory blood pressure monitor (ABPM) and newer wearable devices (EmbracePlus smartwatch device, Biobeat chest patch device, and Aktiia wrist device) will accurately pick up changes in blood pressure caused by 2 different medications (propranolol and pseudoephedrine). The study will last about 29 days excluding the screening period of 28 days.

NCT ID: NCT05659121 Completed - Stroke Clinical Trials

Improving Mobility Via Robotic Exoskeletons in Local Rehabilitation Settings in Singapore

Start date: November 15, 2018
Phase: N/A
Study type: Interventional

The programme is designed to investigate the application of robotic exoskeleton in different levels of local rehabilitation facilities. Feasibilities, efficacy, cost-effectiveness, patient and therapist's view of the application of robotic exoskeleton will be evaluated.

NCT ID: NCT05637749 Completed - Diabetes Mellitus Clinical Trials

Flow Regulation in Medical Serious Games

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to access the effect of facilitation on amount of psychological Flow generated in medical students playing a medical serious game. Students will be randomly assigned to play a serious game designed to revise diabetes management knowledge with and without a facilitator and the amount of Flow experienced compared. They will then be invited to partake in a focus group discussion to elicit insights into the mechanism of action governing facilitator-induced Flow

NCT ID: NCT05635825 Completed - Nutrition, Healthy Clinical Trials

Energy and Nutrient Profiles When Asians Transit From a Meat-based to a Plant-based Diet: A Modelling Exercise

Start date: July 5, 2021
Phase:
Study type: Observational

This study aims to model and present a simulation exercise to assess the nutritional effects of replacing meat-based protein with meat analogues. The hypothesis of our study is to understand if any positive or detrimental effects on nutrition and health will ensue, when people replace a meat-based diet with plant-based and alternative protein substitutes.