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NCT ID: NCT05011513 Terminated - COVID-19 Clinical Trials

Evaluation of Protease Inhibition for COVID-19 in Standard-Risk Patients (EPIC-SR).

Start date: August 25, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The primary hypothesis to be tested is whether or not there is a difference in time to sustained alleviation of all targeted COVID-19 signs and symptoms through Day 28 between PF-07321332/ritonavir and placebo.

NCT ID: NCT04985968 Terminated - Ulcerative Colitis Clinical Trials

The Efficacy and Safety of Cobitolimod in Participants With Moderate to Severe Active Left-Sided Ulcerative Colitis

CONCLUDE
Start date: November 24, 2021
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the efficacy of cobitolimod treatment compared to placebo in inducing clinical remission, in participants with moderate to severe active left-sided UC and to evaluate the efficacy of cobitolimod maintenance treatment compared to placebo in inducing or maintaining clinical remission at week 52, in participants with clinical response at week 6 after induction treatment with cobitolimod.

NCT ID: NCT04947579 Terminated - Clinical trials for Spondylitis, Ankylosing

A Study of CC-99677 in Participants With Active Ankylosing Spondylitis

AS SpA axSpA
Start date: August 25, 2021
Phase: Phase 2
Study type: Interventional

This study is designed to learn about response to CC-99677 treatment by measuring signs and symptoms of Ankylosing Spondylitis (AS), objective measures of disease activity, quality of life assessments, pharmacokinetics, safety, and tolerability over a 12-week double-blind period.

NCT ID: NCT04928430 Terminated - COVID-19 Clinical Trials

Efficacy and Safety of XAV-19 for the Treatment of Moderate-to-severe COVID-19

Start date: April 28, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of XAV-19 drug in patients with moderate-to-severe COVID-19.

NCT ID: NCT04889040 Terminated - COVID-19 Clinical Trials

Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19

MORNINGSKY
Start date: April 28, 2021
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy, safety, antiviral activity, and pharmacokinetics of study drug RO7496998 (AT-527) compared to placebo in non-hospitalized adult and adolescent participants with mild to moderate coronavirus disease 2019 (COVID-19) in the outpatient setting.

NCT ID: NCT04859517 Terminated - COVID-19 Clinical Trials

Evaluation of ADG20 for the Prevention of COVID-19

EVADE
Start date: April 27, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

This placebo-controlled study is intended to evaluate ADG20's safety and ability to prevent COVID-19 infection.

NCT ID: NCT04805671 Terminated - COVID-19 Clinical Trials

Evaluation of ADG20 for the Treatment of Mild or Moderate COVID-19

STAMP
Start date: July 26, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

This placebo controlled study is intended to generate safety and efficacy data in order to provide a treatment option for COVID-19 in patients with a high risk of disease progression based on age or co-morbid medical conditions.

NCT ID: NCT04784559 Terminated - COVID-19 Infection Clinical Trials

Trial to Determine the Efficacy/Safety of Plitidepsin vs Control in Patients With Moderate COVID-19 Infection

Neptuno
Start date: June 4, 2021
Phase: Phase 3
Study type: Interventional

Treatment of patients hospitalised for management of moderate COVID-19 infection

NCT ID: NCT04783727 Terminated - Clinical trials for Bacterial Infections

PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant Tuberculosis

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

PredictEndTB signature is a non-inferiority, prospective, parallel-group open-label randomized controlled trial evaluating the efficacy of individualised antituberculous treatment durations that utilize the transcriptomic signature-based model compared to the standardised twenty months treatment in a cohort of multidrug-resistant tuberculosis patients.

NCT ID: NCT04776044 Terminated - COVID-19 Clinical Trials

Clinical Trial to Evaluate the Safety and Efficacy of ATR-002 in Adult Hospitalized Patients With COVID-19

RESPIRE
Start date: April 12, 2021
Phase: Phase 2
Study type: Interventional

The purpose of the study is to assess the safety and efficacy of ATR-002 (in addition to standard-of-care) for the treatment of COVID-19