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Clinical Trial Summary

This placebo-controlled study is intended to evaluate ADG20's safety and ability to prevent COVID-19 infection.


Clinical Trial Description

This is a Phase 2/3, multicenter, double blind, placebo controlled, randomized study of the mAb ADG20 in the prevention of symptomatic COVID 19 in adults and adolescents with no known history of SARS-CoV-2 infection but whose circumstances place them at increased risk of acquiring SARS-CoV-2 infection and developing symptomatic COVID-19. This objective will be independently evaluated in a cohort of participants with reported recent exposure to an individual diagnosed with a SARS-CoV-2 infection (post-exposure prophylaxis) and in a cohort of participants with no reported exposure to SARS-CoV-2 ( pre-exposure prophylaxis). These cohorts will enrich for participants whose advanced age (≥55 years old) or health status places them at risk for severe COVID 19 or COVID 19 complications. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04859517
Study type Interventional
Source Adagio Therapeutics, Inc.
Contact Study Inquiry
Phone +1 781-819-0080
Email [email protected]
Status Recruiting
Phase Phase 2/Phase 3
Start date April 23, 2021
Completion date March 2023

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