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NCT ID: NCT05980923 Recruiting - Thyroid Dysfunction Clinical Trials

Thyroid Profiles in Patients With Acute Illness

Start date: October 15, 2023
Phase:
Study type: Observational

Patients admitted to the hospital with acute illness may have a wide spectrum of thyroid function abnormalities. It is largely unknown whether such aberrations are temporary or persist for a long time, and whether they impact prognosis of such patients.

NCT ID: NCT05958056 Completed - Athletes Clinical Trials

Low Load Resistance Exercises With Blood Flow Restriction Versus High Load Resistance Exercises

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Practical blood flow restriction (PBFR) is a new technique of reducing the venous return using a band with a pressure that is applied using a perceived pressure scale. The studies that investigate the acute effect of using PBFR and regular high intensity exercises on the level of growth hormone (GH) and blood lactate (BL) after lower extremity training in collegiate athletes are scarce.

NCT ID: NCT05949073 Recruiting - Gingival Recession Clinical Trials

The Impact of Retraction Cords on the Gingival Margin Level.

Start date: July 25, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the relationship between placing specific retraction cord for different periods of time and the post-operative gingival margin level in humans. Determining the amount of immediate reversible and delayed irreversible gingival recession (vertical gingival retraction) that might happen after placing a retraction cord around a natural tooth in healthy humans. It also aims to investigate the impact of mechanical and chemo-mechanical gingival retraction on periodontal health.

NCT ID: NCT05898035 Recruiting - Pain Postoperative Clinical Trials

Postoperative Symptoms Following Endodontic Microsurgery

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Aims: The purpose of this randomized clinical trial is to assess and compare the post operative pain, swelling and quality of life after endodontic microsurgery using either conventional osteotomy or piezoelectric osteotomy . The PICO question that will be used is Does endodontic microsurgery using piezoelectric osteotomy have similar clinical performance in terms of post operative pain and swelling to that of endodontic microsurgery using conventional hand-piece osteotomy. Material and methods: based on solid inclusion criteria , a total of 44 patients in need of endodontic microsurgery will be randomly distributed into two groups (n=22) according to the osteotomy technique: conventional and piezoelectric osteotomy. A standardized microsurgical technique will be employed. After the microsurgery procedure, a pain questionnaire that contain visual analogue scale will be given to each patient to evaluate the pain incidence and intensity at 5 time intervals, 24 hours, 48 hours, 72 hours, 96 hours and 120 hours. The patients will be recalled as well, at days 2 and 7 to evaluate the swelling. Statistical analysis will be performed using chi-square test and linear regression analysis.

NCT ID: NCT05853835 Recruiting - Multiple Sclerosis Clinical Trials

First-in-Human Trial in Healthy Adult Volunteers to Evaluate Safety, Tolerability and PK of LAPIX Study Drug; LPX-TI641

Start date: October 30, 2023
Phase: Phase 1
Study type: Interventional

A Phase I First-in-Human, Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adult Volunteers to Evaluate Safety, Tolerability, and Pharmacokinetics after Single and Multiple Oral Dose of LPX-TI641.

NCT ID: NCT05839223 Completed - Acne Vulgaris Clinical Trials

Clinical Pharmacist Role in Adherence to Recommendations Among Isotretinoin Users

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

The objective of the study was to evaluate the role of clinical pharmacists in improving adherence to medication and the recommendations related to isotretinoin, awareness about proper use, dealing with the side effects, and anxiety and depressive symptoms. Patients were randomly assigned to an intervention group (received the educational process (recommendations) about isotretinoin by a clinical pharmacist in addition to the routine education about isotretinoin provided by the physician) and a control group (received only the routine education about isotretinoin provided by the physician) and then followed for three months. Patient's adherence to the recommendations, patient's knowledge about isotretinoin, and side effects management for both groups were measured through a set of questions adapted from a validated questionnaire at baseline and after three months. Adherence scale was used to evaluate adherence to the medication after three months. Hospital Anxiety and Depression Scale were used to assess depressive and anxiety symptoms at baseline and at follow-up in each group.

NCT ID: NCT05836337 Completed - Breast Cancer Clinical Trials

Clinical Trial Evaluating the Effectiveness of a Tattoo Compared to a Clip Applied to Axillary Lymph Nodes in Breast Cancer Patients Who Undergo SLNBx

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

This study is a single-center prospective, randomized and quasi double blinded pilot study. The study has 2 parallel arms, each arm involved around 54 patients. Targeted community is the newly diagnosed adults with non metastatic and non inflammatory breast cancer in King Hussein Cancer Center who require axillary biopsy as part of their staging work up. The study aims to improve the intra-operative identification of the preoperatively suspicious and biopsied lymph nodes and test the concordance between the pre-operative clinical suspicion and histopathological results of these node; by comparing between preoperative marking of biopsied axillary lymph nodes with two different modalities (clipping Vs tattooing) and testing its concordance with sentinel lymph node biopsy, both in upfront surgery and neoadjuvant chemotherapy settings and in a prospective, randomized and quasi double blinded design

NCT ID: NCT05822349 Recruiting - Type 2 Diabetes Clinical Trials

Effect of Using Pictograms on Improving Depression and Anxiety Among Type 2 Diabetic Patients.

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

we will study the impact of using pictograms on improving depression and anxiety among type 2 diabetic patients, we suppose that patients who received pictograms-enriched labels will have lower levels of depression and anxiety in comparison with those who will not receive after three month follow-up evaluation.

NCT ID: NCT05815875 Completed - Fall Patients Clinical Trials

The Effect of The STEADI Program on Falls and Falls Prevention in Neurosurgical Patients in Jordan

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The goal of this interventional study will be to evaluate the effectiveness of the STEADI Program on falls and falling prevention compared with routine falling assessment in neurosurgical patients in Jordan. The researchers will compare the effectiveness of the STEADI intervention in the intervention group. Participants in the intervention group will be assessed for falls risk using well-established tools as recommended by the Centers for Disease Control and Prevention (CDC). The control group participants will receive regular falling assessment which involves using Morse Fall Scale.

NCT ID: NCT05792748 Completed - Pulpotomy Clinical Trials

Comparison of Zinc Oxide Eugenol to Ferric Sulphate Pulpotomy in Primary Teeth

Start date: January 2, 2013
Phase: N/A
Study type: Interventional

In this prospective randomized, single blinded; split-mouth clinical trial the aim was to evaluate clinical and radiographic effects of placement of reinforced zinc oxide eugenol (ZOE) base directly over the amputated pulp stumps in pulpotomized primary molars, and to compare this technique to ferric sulphate (FS) in pulpotomized primary teeth. Included were 65 children using a split-mouth design, (130 teeth). All teeth were then restored with prefabricated stainless steel crowns (SSC). Patients were recalled for clinical and radiographical evaluation after 3, 6, 12 and 24 months. Two experienced and calibrated pediatric dentists who were not involved in the investigation blindly assessed the radiographs.