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NCT ID: NCT03703869 Recruiting - Diabetes Clinical Trials

Twelve -Month Study Observing How Insulin-naïve Patients With Type 2 Diabetes Mellitus Manage Diabetes Using Toujeo® After Oral Antidiabetic Drug Failure, the Side Effect of Toujeo®, and The Cost.

ATOS
Start date: March 6, 2018
Phase:
Study type: Observational

Primary Objective: Assess effectiveness of insulin glargine (U300) in achieving glycemic goal measured by hemoglobin A1c (HbA1c). Secondary Objectives: - Assess effectiveness in achieving glycemic goal measured by HbA1c; - Assess effectiveness on change in HbA1c, fasting plasma glucose (FPG) and self-monitored plasma glucose (SMPG) ; - Assess requirement for intensification of therapy by additional antidiabetics. - Assess incidence of hypoglycemia; - Assess other safety endpoints: adverse events (AEs), serious adverse events (SAEs); - Assess change in body weight.

NCT ID: NCT03684122 Recruiting - Parkinson Disease Clinical Trials

Use of Mesenchymal Stem Cells in Parkinson Disease (PD)

Start date: June 24, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This study aims to examine the short term and long term safety outcomes of the treatment of PD patients with umbilical cord derived stem cells as indicated by the presence of adverse events that are confirmed to be related to the therapy.

NCT ID: NCT03625388 Not yet recruiting - Clinical trials for Chronic Myelogenous Leukemia

Low Dose Dasatinib (50 mg Daily) as First-line Treatment for Newly Diagnosed Chronic‐Phase Chronic Myeloid Leukemia

Start date: October 2018
Phase: Phase 2
Study type: Interventional

The purpose of this multicenter randomized study is to compare efficacy and safety of dasatinib 50 mg once daily and dasatinib 100 mg once daily in patients with early chronic phase (CP) chronic myeloid leukemia (CML)

NCT ID: NCT03571139 Recruiting - Clinical trials for Diabetic Retinopathy

Detecting the Influence of Cataract Surgery on the Development of Diabetic Retinopathy in Patients With Diabetes Mellitus Type 2 With and Without Diabetic Retinopathy Using OCT Angiography

Start date: June 1, 2018
Phase:
Study type: Observational

Detecting the influence of cataract surgery on the development of diabetic retinopathy in patients with diabetes mellitus type 2 with and without diabetic retinopathy using OCT angiography.

NCT ID: NCT03526315 Completed - Oral Health Clinical Trials

Antimicrobial Effect of Different Pastes on Streptococcus Mutans in Children

Start date: March 2016
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial involving 127 children ages between 4 and 5 years to investigate the efficacy of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) in reducing Streptococcus mutans (S. mutans) bacteria, and compare that with fluoride alone, or combined use of fluoride and CPP-ACP over a 6 month period using Saliva Check Mutans kits to detect Mutans Streptococci (MS). It is expected that all used anti-cariogenic agents will have the ability to reduce the S. mutans level in different values.

NCT ID: NCT03526276 Completed - Clinical trials for White Spot Lesion of Tooth

Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth

Start date: March 2016
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial involving 118 children ages between 4 and 5 years to assess the remineralization effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) on white spot lesions in primary teeth using Quantitative Light-induced Fluorescence (QLF) system, and compare that with fluoride alone or combined use of fluoride and CPP-ACP.

NCT ID: NCT03522051 Active, not recruiting - Pulpotomy Clinical Trials

Assessment of Pulpotomy Procedure Using NeoMTA Plus in Permanent Teeth With Carious Exposure

PULPOTOMY
Start date: December 1, 2016
Phase: N/A
Study type: Interventional

Many deep carious teeth are treated unnecessarily by root canal therapy, while with using current techniques and advances in compatible dental materials in addition to better understanding of biological response of the dental pulp, many can be treated conservatively via vital pulp therapy procedures.

NCT ID: NCT03517982 Completed - Clinical trials for Acute Transplant Rejection in Patients Receiving Allogeneic Renal Transplant

Generic Mycophenolate Mofetil Safety Study for Prophylaxis in de Novo Renal Transplant Patients in Jordan

MyOra-PASS
Start date: October 2014
Phase:
Study type: Observational

The purpose of this observational study was to assess the safety and efficacy of generic mycophenolate mofetil in de novo renal transplant patients in Jordan where no visits or intervention(s) additional to the daily practice were performed.

NCT ID: NCT03507556 Recruiting - Revascularization Clinical Trials

Regeneration of Immature Teeth. Case Series

Start date: June 28, 2010
Phase: N/A
Study type: Interventional

This clinical study aims to investigate the predictability of revascularization procedure of immature necrotic human permanent teeth with apical periodontitis. The quality of root development (thickness and length) will be assessed radiographically.

NCT ID: NCT03503630 Recruiting - Clinical trials for Locally Advanced Rectal Cancer

Short-course Radiation Followed by mFOLFOX-6 Plus COMPOUND 2055269 for Locally-advanced Rectal Adenocarcinoma

Start date: July 20, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to show that the addition of COMPOUND 2055269, an immunotherapeutic drug, to Folfox chemotherapy will improve the pathologic complete response rate in patients with locally advanced rectal cancer.