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NCT ID: NCT06205134 Completed - Anaphylaxis Clinical Trials

Comparative Bioavailability of Intranasal Epinephrine

Start date: August 22, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

A Study to Compare the Bioavailability of Epinephrine following a Single Nasal Dose of FMXIN002 Microspheres Powder 3.6 mg, and 4mg with EpiPen 0.3mg Intramuscular Injection in Healthy Adults

NCT ID: NCT06204575 Completed - Clinical trials for Dementia With Lewy Bodies

Focused Ultrasound Thalamotomy for Tremor Relief in Atypical Parkinsonism

FUSAP
Start date: November 1, 2013
Phase:
Study type: Observational

The goal of this retrospective observational study is to describe the efficacy of focused ultrasound ventral-intermediate nucleus thalamotomy in patients with atypical parkinsonism. - Is this treatment efficacious in patients with multiple system atrophy? - Is this treatment efficacious in patients with diffuse Lewy Body Dementia? Data will be collected from patients charts.

NCT ID: NCT06202274 Recruiting - Acne Clinical Trials

Clinical Study to Evaluate the Safety and Efficacy of Candela Technology

Start date: October 4, 2023
Phase: N/A
Study type: Interventional

This is a non-randomized, multi-center, open-label, prospective clinical study evaluating the clinical treatment with Candela Medical Technology.

NCT ID: NCT06202248 Recruiting - Clinical trials for Non-metastatic Prostate Cancer

A Study to Assess Alpha DaRT224 for the Treatment of Men With Non-metastatic Locally Recurrent Prostate Cancer

Start date: March 12, 2024
Phase: N/A
Study type: Interventional

This is a multi-center clinical study enrolling up to 10 participants. The purpose of this study is to assess the feasibility and safety of intratumoral DaRT seeds implantation for the treatment of locally recurrent prostate cancer. Secondary objectives are to 1. To evaluate feasibility of interstitial radiotherapy using DaRT seeds. Feasibility will be determined according to the rate of successful placement of DaRT seeds via imaging [Timeframe: immediately following the insertion procedure 2. To assess the impact of DaRT seeds on patient reported quality of life.

NCT ID: NCT06202118 Recruiting - Breast Cancer Clinical Trials

A Study of Diffusing Alpha Radiation Therapy for Patients With Breast Carcinoma in Frail or Elderly Patients.

Start date: February 19, 2024
Phase: N/A
Study type: Interventional

A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for the treatment of newly diagnosed or Recurrent Breast Carcinoma in frail or elderly patients.

NCT ID: NCT06201728 Enrolling by invitation - Asthma Clinical Trials

The Effect of Asthma Flare-up Clinic After Exacerbation

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The goal of this interventional study is to examine the effect of asthma flare-up clinic follow-up in adult subjects after an asthma flare-up. This study aim to answer the following questions: 1. Does a follow-up in a flare-up clinic improves disease outcomes? 2. Does a follow-up in a flare-up clinic improves disease management? Participants in the intervention group will take part in a structured follow-up at the asthma flare-up clinic at three time points. Each visit will include questionnaires, pulmonologist examination and consultation, laboratory tests and spirometry. The control group will undergo phone-call follow-up with a research coordinator in similar time frames as the intervention. Researchers will compare the two groups to see if the clinic follow-up affects the study outcomes.

NCT ID: NCT06197464 Completed - Control Clinical Trials

FLOAT Through Anxiety: Virtual Reality Application's Efficacy as a Tool to Distract From Negative Emotions and Thoughts

Start date: March 12, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to examine the effectiveness and safety of the VR FLOAT application as a tool to reduce negative thoughts and feelings and anxiety symptoms in students with high levels of stress and anxiety. The main questions it aims to answer are: 1. Will subjects with high levels of anxiety who will use the FLOAT application experience a more significant relief in feelings of anxiety compared to subjects in the control group? 2. Will subjects who are used to using technology find greater comfort in using VR compared to subjects who are not used to it? 3. What is the degree of satisfaction with the use of VR and are there any reports of side effects?Participants will [describe the main tasks participants will be asked to do, treatments they'll be given and use bullets Researchers will compare control group to see The comparison between using FLOAT as a regulation strategy after psychoeducation on emotional regulation and cognitive-behavioral use of a regulation strategy after the same psychoeducation

NCT ID: NCT06196528 Recruiting - Clinical trials for Wrist Osteoarthritis

WristArt Total Wrist Arthroplasty Implant First In Human Study

Start date: January 2, 2024
Phase: N/A
Study type: Interventional

The WristArt implant will be implanted for the first time in humans' wrists

NCT ID: NCT06196359 Completed - Rehabilitation Clinical Trials

Assessing Function and Pain After Total Knee Arthroplasty With Combined Femoral and Popliteal Nerve Block

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The goal of this interventional study is to examine whether a pain management technique of combined femoral and popliteal nerve block is effective in total knee arthroplasty patients. The main questions it aims to answer are: Are there differences in postoperative outcomes? Does the nerve block, age, preoperative quadriceps muscle strength and Oxford Knee Score of the patient predict early functional ability? Participants underwent total knee arthroplasty and assessments. Researchers compared pain management techniques to assess effects on postoperative outcomes and identified the importance of preoperative variables a predictors of early functional ability. Further research is required to refine postoperative pain management strategies.

NCT ID: NCT06196346 Recruiting - Clinical trials for Major Depressive Disorder

Inter-Brain Synchrony in Psychotherapy for Depression

IBSPD
Start date: November 23, 2021
Phase: N/A
Study type: Interventional

The study aims to examine inter-brain synchrony between patients and therapists over the course of psychotherapy. Twenty patients will undergo a 16-session course of psychotherapy for major depressive disorder. The protocol used will be supportive-expressive psychotherapy (see Luborsky et al., 1995). Participants will also undergo Hamilton depression interviews a week before treatment, before every session and a week after treatment. functional near-infrared spectroscopy (fNIRS) imaging will be used to record brain activity during every other session (sessions 1, 3, 5, 7, 9, 11, 13, 15) as well as during interviews at baseline, on session 8 and at followup. Saliva samples will be collected during the same sessions to measure hormone and cytokine levels during the same sessions. Participants completed questionnaires before and after the study, and before and after each session. The researchers hypothesized that synchrony will gradually increase over the psychotherapy sessions, and that synchrony in the pre-treatment interview will be lower than in the post-treatment interview.