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NCT ID: NCT05486065 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight

Start date: August 8, 2022
Phase: Phase 2
Study type: Interventional

This study compares how three doses of semaglutide work in participants with type 2 diabetes (T2D) and overweight who are taking metformin. The study will look mainly at how well participant's blood sugar and participant's body weight are controlled when they are taking the study medicine at different doses. Participants will either get semaglutide [2 milligrams (mg), 8 mg, or 16 mg] or semaglutide placebo (a dummy medicine). Participants will take the study medicine with an injection pen called NovoPen®4. The injection pen is a medical tool with a needle used to inject the study medicine under the skin. The study will last for about 52 weeks. Participants will have 13 clinic visits and 4 phone calls.

NCT ID: NCT05484362 Completed - Blood Pressure Clinical Trials

Acute Effect of Crocus Sativus on Postprandial Glycemia

Start date: June 6, 2022
Phase: N/A
Study type: Interventional

This study investigated the effects of two different doses of Crocus Sativus in glucose beverages on glycemic responses.

NCT ID: NCT05484336 Completed - Blood Pressure Clinical Trials

Acute Effects of Spirulina on Postprandial Glycemic Responses and Arterial Blood Pressure

Start date: June 7, 2022
Phase: N/A
Study type: Interventional

This study investigated the effects of three doses of spirulina in glucose beverages on postprandial glycemic responses, arterial blood pressure, and subjective satiety.

NCT ID: NCT05484323 Completed - Blood Pressure Clinical Trials

Acute Effects of Cookies Containing 2.5 g Spirulina on Postprandial Glycemic and Insulin Responses

Start date: January 15, 2022
Phase: N/A
Study type: Interventional

This study investigated the effects of cookies containing 2.5 g Spirulina on postprandial glycemic and insulin responses.

NCT ID: NCT05481216 Completed - COVID-19 Clinical Trials

HIV-1 & Coronavirus-Coinfection in Europe: Morbidity & Risk Factors of COVID-19 in People Living With HIV

HIV CoCo
Start date: March 29, 2022
Phase:
Study type: Observational

HIV CoCo is a European multi-centre, multi-country, retrospective, observational case-control study that will aim to describe clinical outcomes and identify risk factors for People Living With HIV (PLWHIV) who are co-infected with the SARS-CoV-2 coronavirus. The study will address two central questions: 1. Is there a particular risk for COVID-19 in PLWHIV as compared to HIV seronegative control COVID-19 cases? 2. Are there particular factors, within the group of PLWHIV, which put them at risk for a more severe COVID-19 disease course? The study will address these questions by recruiting patients co-infected with both HIV and SARS-CoV-2 and comparing them to two control groups - one group infected with SARS-CoV-2 only and another group infected with HIV only. Only deidentified, real-world retrospective data will be used for the study, collected as part of standard, routine clinical care. Additionally, this study will also look to: 1. Describe the differences in the clinical manifestation of COVID-19 in PLWHIV compared to HIV seronegative controls 2. Describe the response to treatment, including supportive care and novel therapies against COVID-19, including antiviral or immunomodulatory therapy 3. Describe the co-morbidities in PLWHIV and controls with COVID-19 4. Compare the severity of COVID-19 between PLWHIV and the COVID-19 only controls at diagnosis and hospital admission. Data will be collected about patient outcomes from COVID-19 (including hospitalisation for COVID-19, length of stay in hospital, critical care admission, ventilation/oxygenation requirements, and need for kidney replacement therapy), as well as pre-existing health conditions, and relevant blood results at COVID-19 diagnosis.

NCT ID: NCT05480969 Completed - Heart Failure Clinical Trials

Nurse-led Educational Intervention on Heart Failure Patients

Start date: April 19, 2019
Phase: N/A
Study type: Interventional

A randomized controlled study to examine the effect of a nurse-led, home/telephone or telephone-only educational intervention on outcomes of heart failure patients and their caregivers.

NCT ID: NCT05473455 Completed - Infertility Clinical Trials

Value of Follicular Flushing. Randomised Controlled Trial

Start date: July 15, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate whether the addition of follicular flushing to the initial aspiration during oocyte retrieval increases the number of oocytes retrieved in women undergoing ovarian stimulation.

NCT ID: NCT05466409 Completed - Airway Management Clinical Trials

Upper Airway Ultrasound Training Requirements

Start date: November 29, 2021
Phase:
Study type: Observational

The applications of point-of-care ultrasonography (POCUS) of the upper airway are growing over the last decade. It's clinical applications include both diagnosis of upper airway pathology as well as pre-intubation airway examination and provision of ultrasound markers of difficult laryngoscopy and/or intubation. However, it is differentiated from the comprehensive ultrasound examinations traditionally performed by radiologists because it is targeted to answer a specific clinical question in real time. Moreover, ultrasound-guided techniques require knowledge of sonoanatomy and ultrasound operational skills. However, clinicians lack the standardized training that ultrasound technicians and radiologists receive. POCUS training is rarely done in a standardized manner, and even more so, POCUS is rarely conducted under expert's supervision. The current study investigates the feasibility of upper airway POCUS performed on healthy volunteers by anaesthesia residents using a predefined scanning protocol after attending a structured training course. Assessment of anaesthesia trainees' competence and minimum training requirements were the aim of the study.

NCT ID: NCT05464342 Completed - Fatigue Clinical Trials

Integral Physiological Adaptations to Carbohydrate Periodization

IPACP
Start date: July 5, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effect of long-term carbohydrate periodization protocols on sleep architecture, sleep quality, daytime sleepiness, physical performance, body composition, gut microbiome, and miRNA in healthy trained individuals.

NCT ID: NCT05459883 Completed - Ischemia Clinical Trials

Splenic Artery Ligation and Portocaval Shunt in Small-for-size Syndrome

splen ligation
Start date: January 1, 2017
Phase:
Study type: Observational

Our study aimed at assessing the changes of portal vein pressure, portal vein flow and hepatic arterial flow (HAF) in liver remnants ≤ 30% of the standard liver volume by reducing portal vein overflow via ligation of the splenic artery.