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NCT ID: NCT05730192 Recruiting - Colorectal Cancer Clinical Trials

EAGLE Trial CADDIE Artificial Intelligence Endoscopy

EAGLE
Start date: May 10, 2023
Phase: N/A
Study type: Interventional

The EAGLE study is a prospective randomized controlled multicenter parallel design trial, for the assessment of clinical performance of the CADDIE device and to confirm that the device performs as expected.

NCT ID: NCT05728489 Recruiting - Psoriasis Clinical Trials

A Study to Test How Well Different Doses of BI 765250 Are Tolerated by People With a Skin Disease Called Plaque Psoriasis

Start date: March 9, 2023
Phase: Phase 1
Study type: Interventional

This study is open to adults with plaque psoriasis. The main purpose of this study is to find out whether people with plaque psoriasis can tolerate a medicine called BI 765250. Another purpose is to check whether BI 765250 can improve participants' skin condition. Participants are divided into 4 groups. Each group gets a different dose of BI 765250 or placebo as an infusion or injection. Placebo infusions and injections look like BI 765250 but do not contain any medicine. It is decided by chance, who gets BI 765250 and who gets placebo. During the first 2 weeks, participants get the study medicine as an infusion into a vein once a week. Afterwards, they get the study medicine as an injection under the skin every 2 weeks. In total, every participant gets 5 injections. Participants are in the study for about 8 months. During this time, they visit the study site 23 times. On 2 of the visits, participants stay overnight at the study site, once for 2 nights and once for 1 night. The doctors collect information on any health problems of the participants. They also regularly check participants' skin condition.

NCT ID: NCT05712824 Recruiting - Heart Failure Clinical Trials

V-Lap System For Wirelessly Measuring And Monitoring Left Atrial Pressure (LAP) In Patients With Advance CHF

Start date: December 20, 2021
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the safety and performance of the V-LAP System in subjects with New York Heart Association (NYHA) functional class II and III HF, irrespective of left ventricular ejection fraction.

NCT ID: NCT05705167 Terminated - COVID-19 Clinical Trials

Plitidepsin Versus Control in Immunocompromised Adult Participants With Symptomatic COVID-19 Requiring Hospital Care

NEREIDA
Start date: April 19, 2023
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate efficacy of plitidepsin in pre-specified groups of immunocompromised patients with symptomatic COVID-19 requiring hospital care versus control in terms of mortality.

NCT ID: NCT05695716 Withdrawn - Clinical trials for Coronary Artery Disease

CSI Percutaneous Ventricular Assist Device (pVAD) Second in Human Study

Start date: April 5, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to collect data on safety and device performance on the CSI pVAD System used to support hemodynamic stability during HR-PCIs to inform device design and finalization.

NCT ID: NCT05692518 Active, not recruiting - Obesity Clinical Trials

MagDI Diversion Feasibility Study

Start date: December 19, 2022
Phase: N/A
Study type: Interventional

The purpose of this clinical research study is to evaluate the feasibility of the GT Metabolic Solutions DI Bio-fragmentable Magnetic Anastomosis System (MAGNET System, DI Bio-fragmentable) for creation of a side-by-side anastomosis duodeno-ileostomy in obese adults.

NCT ID: NCT05688852 Active, not recruiting - Crohn Disease Clinical Trials

VTX958 for the Treatment of Moderately to Severely Active Crohn's Disease

Harmony-CD
Start date: December 22, 2022
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, double-blind placebo-controlled, parallel group study to evaluate the efficacy and safety of VTX958 in participants with moderately to severely active Crohn's Disease.

NCT ID: NCT05685615 Recruiting - Clinical trials for Ventilator Associated Pneumonia

PK of BV100 in Patients VABP Suspected or Confirmed to be Due to CRAB

Start date: April 20, 2023
Phase: Phase 2
Study type: Interventional

A multicenter Phase 2 study to evaluate the pharmacokinetics, efficacy, and safety of intravenous BV100 combined with Polymyxin B in adult patients with VABP suspected or confirmed to be due to CRAB

NCT ID: NCT05685303 Enrolling by invitation - Heart Failure Clinical Trials

Alleviant ALLAY-HF Study

Start date: January 10, 2023
Phase: N/A
Study type: Interventional

Prospective, multicenter, randomized, sham-controlled, double blinded, adaptive study designed to evaluate the safety and efficacy of a percutaneously created interatrial shunt using the Alleviant ALV1 System in patients with HFpEF/HFmrEF.

NCT ID: NCT05682066 Recruiting - Clinical trials for Mitral Valve Regurgitation (Degenerative or Functional)

TVMR With the Innovalve System Trial - Pilot in Georgia

TWIST-PILOT-GE
Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Study to evaluate the safety and performance of the Innovalve mitral valve replacement system