Clinical Trials Logo

Filter by:
NCT ID: NCT01990105 Completed - Atrial Fibrillation Clinical Trials

Treatment of Atrial Fibrillation in Finland

FinFib2
Start date: November 2013
Phase: N/A
Study type: Observational

FINFIB 2 is an observational investigator-driven study that seeks to examine current treatment practice for atrial fibrillation in Finland. The investigators hypothesis is that the treatment of atrial fibrillation has improved since the introduction of new antiarrhythmic drugs and anticoagulants.

NCT ID: NCT01989936 Completed - Clinical trials for Migraine With or Without Aura

Eletriptan for the Treatment of Migraine in Patients With Previous Poor Response or Tolerance to Oral Sumatriptan

Start date: January 1999
Phase: Phase 3
Study type: Interventional

To determine the tolerability and efficacy of eletriptan in patients who had discontinued oral sumatriptan due to lack of efficacy or intolerable adverse events (AEs) during previous clinical treatment (not a controlled trial).

NCT ID: NCT01987284 Completed - Clinical trials for Isolated Systolic Hypertension

SER100 in Isolated Systolic Hypertension

Start date: October 2013
Phase: Phase 2
Study type: Interventional

Isolated Systolic Hypertension (ISH)is the dominating hypertensive disease in elderly people. Much attention has recently been drawn to the strong relationship between the systolic blood pressure and cardiovascular morbidity. In previous clinical studies carried out in individuals with normal blood pressure at baseline SER100 decreased primarily the systolic blood pressure. It is hypothesized that the effect on systolic blood pressure in hypertensive patients will be larger or equal to the fall seen in normotensive patients.

NCT ID: NCT01985503 Completed - Obesity Clinical Trials

Longitudinal Follow-up of Brown Adipose Tissue Function and Structure

BATFollowUp
Start date: January 2015
Phase:
Study type: Observational [Patient Registry]

In Turku PET Centre, there have been 3 positron emission tomography studies on brown adipose tissue (BAT) activity in healthy adults. BATPET was performed between 2008 and 2009. FATBAT started in 2011 and Dixon-BAT in 2012 and they are both currently ongoing. In the current study, participants of BATPET, FATBAT and Dixon-BAT studies are recruited for a follow-up study to examine associations between obesity, cardiovascular risk factors, serum metabolic profile and BAT structure at baseline and during follow-up several years later. 43 BATPET participants will be called for follow-up in 2013 with a follow-up period of 5 years and 52 FATBAT and Dixon-BAT participants in years 2014 and 2015 with a follow-up period of 3 years. The aim of this study is to examine longitudinal associations between BAT function and structure, liver adiposity and cardiovascular risk factors at baseline and during follow-up.

NCT ID: NCT01982292 Completed - Clinical trials for Chronic Heart Failure

Safety of Repeat Doses of IV Serelaxin in Subjects With Chronic Heart Failure

RELAX-REPEAT
Start date: May 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety of repeat doses of serelaxin in chronic heart failure. At the same time, markers of efficacy will also be collected as exploratory measures.

NCT ID: NCT01978691 Completed - Obesity Clinical Trials

The Effect of a Bifidobacterium and Polydextrose on Body Fat Mass

MetSProb
Start date: November 2013
Phase: Phase 2
Study type: Interventional

Obesity is a major problem worldwide, and it is related to abnormalities in glucose and lipid metabolism. The purpose of this study is to investigate the effect of a dietary supplement containing probiotic (Bifidobacterium animalis ssp. lactis 420) and/or prebiotic (Litesse) on change in body fat mass in a double-blind, randomized, placebo-controlled intervention trial. The supplement is ingested once per day for the duration of six months, and participants will attend a follow-up visit one month after the end of the intervention. The study will enroll 232 participants (58 per study arm) in four research centers in southern Finland.

NCT ID: NCT01977651 Completed - Clinical trials for Metastatic Castration-resistant Prostate Cancer (mCRPC)

A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide

UPWARD
Start date: September 25, 2013
Phase: Phase 4
Study type: Interventional

The objective of this study was to evaluate the incidence of seizures and monitor the safety of enzalutamide treatment in participants with metastatic castration-resistant prostate cancer (mCRPC) known to have risk factor(s) for seizure.

NCT ID: NCT01974752 Completed - Uveal Melanoma Clinical Trials

Selumetinib (AZD6244: ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT)

SUMIT
Start date: April 2014
Phase: Phase 3
Study type: Interventional

Selumetinib therapy in patients with metastatic uveal melanoma.

NCT ID: NCT01973231 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes

LIRA-LIXI™
Start date: October 2013
Phase: Phase 4
Study type: Interventional

This trial is conducted in Europe. The aim of the trial is to investigate the efficacy and safety of liraglutide versus lixisenatide as add-on to metformin in subjects with type 2 diabetes (T2DM).

NCT ID: NCT01972841 Completed - Overactive Bladder Clinical Trials

This Was a Multinational Study Comparing the Efficacy and Safety of Two Medicines , Solifenacin Succinate and Mirabegron Taken Together, or Separately, or a Mock Treatment (Placebo) in Subjects With Symptoms of Overactive Bladder

SYNERGY
Start date: November 5, 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study was to examine how well two medicines (solifenacin succinate and mirabegron) combined work compared to each medicine alone in the treatment of bladder problems.