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NCT ID: NCT03408730 Completed - Clinical trials for Hepatitis B Vaccines

Lot-to-lot Consistency of Sci-B-Vac™ in Adults

Start date: December 14, 2017
Phase: Phase 3
Study type: Interventional

A Controlled Trial to Assess the Lot-to-lot Consistency of Sci-B-Vac™ in Adults

NCT ID: NCT03408197 Completed - Clinical trials for Hypothermia, Accidental

Two Warming Methods in Knee Arthroplasty

Start date: November 19, 2018
Phase: N/A
Study type: Interventional

In this study two warming methods will be compared in knee arthroplasty surgery. Barrier EasyWarm will be used in the study group and BairHugger upper body warming blanket in the control group. Both groups will be prewarmed 30 minutes before spinal anaesthesia. In the operating room warming will be continued with the same warming method. Primary end point is core temperature after arriving to post anaesthesia care unit. Hypothesis is that Barrier EasyWarm is not inferior to BairHugger in preventing inadvertent intraoperative hypothermia. Few methods exist to measure the core temperature non-invasively. Zero-heat-flux technique is used in this study. During the study we will test the accuracy of the 3M BairHugger Temperature Monitoring System by placing two sensors onto the patients (n = 30) fore head. After that the accuracy of the Dräger Tcore is examined by comparing it with the 3M BairHugger Temperature Monitoring System. So the patients (n=30) have both these different core temperature monitoring systems on their foreheads. This observational monitoring study is performed from the patient number 80 until the end.

NCT ID: NCT03402841 Completed - Clinical trials for Non-Germline BRCA Mutated Ovarian Cancer

Multicentre Study of Olaparib Maintenance Monotherapy in Platinum Sensitive Relapsed Non gBRCAm Ovarian Cancer Patients

OPINION
Start date: January 30, 2018
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the efficacy and safety of single-agent olaparib as a maintenance treatment in patients with relapsed High Grade Serous Ovarian Cancer (including patients with primary peritoneal and/or fallopian tube cancer) or high grade endometrioid cancer who do not have known deleterious or suspected deleterious germline BRCA mutations (non-gBRCAm) and who had responded following platinum based chemotherapy

NCT ID: NCT03400241 Completed - Healthy Subjects Clinical Trials

Pharmacokinetic Study Comparing Tiotropium Easyhaler and Spiriva Handihaler

Start date: February 19, 2018
Phase: Phase 1
Study type: Interventional

Absorption of inhaled tiotropium is compared between three Tiotropium Easyhaler products and Spiriva capsules inhaled via HandiHaler. All subjects will receive all products as a single dose.

NCT ID: NCT03400059 Completed - Chronic Migraine Clinical Trials

Study to Evaluate the Efficacy of Intranasal Kinetic Oscillation Stimulation in the Preventive Treatment of Chronic Migraine

Start date: March 22, 2018
Phase: N/A
Study type: Interventional

The efficacy of intranasal kinetic oscillation stimulation using the Chordate System S211 as a preventative treatment will be examined in patients diagnosed with chronic migraine. The medical device system will be applied in 6 treatments at weekly intervals. The study will examine the effects on monthly headache days with moderate to severe intensity.

NCT ID: NCT03399721 Completed - Nasal Congestion Clinical Trials

Investigation of Kinetic Oscillation Stimulation by the Chordate System S101 in the Treatment of Non Allergic Rhinitis

KOSNAR
Start date: May 7, 2018
Phase: N/A
Study type: Interventional

This is an interventional, multicenter, double-blind, placebo-controlled trial in which patients diagnosed with non-allergic rhinitis will be randomized to either intranasal stimulation, or placebo treatment with the Chordate System at two occasions.

NCT ID: NCT03394742 Completed - Breast Cancer Clinical Trials

Effectiveness of Peer Support on Quality of Life in Recently Diagnosed Breast Cancer Patients

Start date: May 1, 2014
Phase: N/A
Study type: Interventional

This study examines effectiveness of peer support of breast cancer patients. Half of the participants received peer support via telephone in addition to usual care and another half are give the usual care only.

NCT ID: NCT03393754 Completed - Clinical trials for Hepatitis B Vaccines

Immunogenicity and Safety of Sci-B-Vac® to Engerix-B® in Adults

Start date: December 13, 2017
Phase: Phase 3
Study type: Interventional

This study is a double-blind randomized controlled trial designed to establish the non-inferiority of Sci-B-Vac® compared to Engerix-B® in adults ≥ 18 years old and the superiority of Sci-B-Vac® compared to Engerix-B® in ≥ 45 years old.

NCT ID: NCT03391596 Completed - Quality of Life Clinical Trials

Internet-based Intervention for Enhancing the Psychological Well-being of Elderly Caregivers

CareACT
Start date: December 1, 2016
Phase: N/A
Study type: Interventional

This study will examine whether an Internet-based Acceptance and Commitment Therapy (ACT) intervention is effective, firstly, on reducing depressive symptoms, and, secondly, on improving well-being of elderly family caregivers. In our study, we will compare 1) the experimental Internet-based ACT group to 2) standardized institutional rehabilitation carried out in rehabilitation centers and to 3) support provided by voluntary family caregiver associations

NCT ID: NCT03387683 Completed - Clinical trials for Diabetes Mellitus Type 2

A Clinical Study to Investigate the Effects of Dapagliflozin on Heart Work, Heart Nutrient Uptake, and Heart Muscle Efficiency in Type 2 Diabetes Patients

DAPACARD
Start date: February 28, 2018
Phase: Phase 4
Study type: Interventional

This is a randomised, placebo-controlled, double-blind, parallel-group, international, multicentre, Phase IV study to investigate the effects of dapagliflozin on cardiac substrate uptake, myocardial efficiency and myocardial contractile work in T2D patients. Eligible subjects with T2D before randomisation and fulfilling all of the inclusion criteria and none of the exclusion criteria will be randomised in a 1:1 ratio to dapagliflozin 10 mg or placebo once daily and treated for six weeks. The study includes five visits.