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NCT ID: NCT06443788 Recruiting - Clinical trials for Preterm Premature Rupture of Membrane

Trans-perineal Ultrasound in Assessment of PPROMs

Start date: February 15, 2024
Phase: N/A
Study type: Interventional

Accurate and timely diagnosis of preterm pre-labor rupture of membranes (PPROM) is important to prevent adverse maternal and fetal outcomes. Following a history of PPROM, physical examination should be performed in a way that minimizes the risk of infection using a speculum. This is important to confirm the diagnosis by visualizing the amniotic fluid passing from the cervical canal or pooling in the vagina. In addition to examining the cervix to assess its dilatation and effacement and look for umbilical cord prolapse or fetal prolapse. However, Pelvic exam is one of the most common anxiety provoking medical procedures that's why this study aims at using the transperineal ultrasound as a non-invasive, accurate, cost effective, applicable and readily available tool in assessment of PPROM with less patient anxiety and fear.

NCT ID: NCT06443476 Recruiting - Clinical trials for Posterior Atrophic Mandible

Tenting Abutment Technique Versus Screw"Tent-Pole" Technique for Augmentation of Posterior Atrophic Mandible

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

To evaluate a novel method using a designed tenting abutment to reduce number of surgeries and the edentulous healing period is shortened. In addition, to prevent vertical and horizontal collapse of the bone graft and minimizes resorption of the bone graft during the healing the atrophic posterior mandible. The tent pole provides excellent mechanical properties; stability & fixation, yet very poor features to preserve the integrity of the soft tissue. Using the tenting abutment technique will help preserve the soft tissue and decrease the amount of dehiscence that might accompany the use of the tent pole.

NCT ID: NCT06443437 Recruiting - Fear of Pain Clinical Trials

Effect of Bee-buzzy Vibrating Cold Application and Marionette Doll on Pain and Fear During Phlebotomy

Start date: May 31, 2024
Phase: N/A
Study type: Interventional

Non-pharmacological methods are often used as a creative strategy to reduce pain and fear in children during a painful procedure such as phlebotomy. In this context, external vibratory cold application and a marionette doll are a commonly used as non-pharmacological distraction method to reduce pain and fear. In the literature, there are studies with cold application, vibrating devices and a marionette doll in bee appearance therefor this study is aimed to evaluate the effect of bee-buzzy vibrating cold application and marionette doll on pain and fear during phlebotomy among preschool children.

NCT ID: NCT06442124 Recruiting - Obesity Clinical Trials

The Effect of BMI on Gluteus Maximum Activity in Adulthood With Sacroiliac Dysfunction

Start date: May 12, 2024
Phase:
Study type: Observational

PURPOSE: This study will be conducted to investigate the effect of BMI on gluteus maximum activity in adulthood with sacroiliac dysfunction BACKGROUND: Sacroiliac joint (SIJ) pain is pain arising from SIJ structures and SIJ dysfunction (SIJD) generally refers to aberrant position or movement of SIJ structures . An estimated 15-30% of all low back pain cases are due to SIJ pain The present study will be conducted to add a new information to the body of knowledge of physical therapy profession as it will investigate the effect of BMI on gluteus maximum activity in adulthood with sacroiliac dysfunction HYPOTHESES: . •There will be no effect of BMI on gluteus maximum activity in adulthood with sacroiliac dysfunction RESEARCH QUESTION: - Do BMI has an effect on gluteus maximum activity in adulthood with sacroiliac dysfunction?

NCT ID: NCT06441591 Recruiting - Clinical trials for Diabetic Kidney Disease

Clinical Outcome of Vinpocetine in Diabetic Nephropathy

Start date: June 1, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this controlled, randomized, clinical trial is to evaluate the effect of vinpocetine on clinical outcomes on the diabetic nephropathy patients. The following will be evaluated; anthropometrics, kidney functions, glucose panel, lipid panel, ICAM-1, quality of life. Participants will receive either vinpocetine or placebo, twice daily for 3 months.

NCT ID: NCT06441279 Recruiting - TMJ Disc Disorder Clinical Trials

Treatment of Tempromandibular Joint Anterior Disc Displacement With Different Materials

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

comparing the clinical efficacy of intra-articular injection of platelet lysate (PL), versus Hyaluronic Acid after arthrocentesis in the management of patients with anterior disc displacement with reduction.

NCT ID: NCT06438523 Recruiting - Clinical trials for Pulpitis - Irreversible

A-prf,Nanochitosan Combined With A-prf Compared to Chitosan for Symptomatic Irreversible Pulpitis of Mature Teeth

Start date: September 2, 2023
Phase: N/A
Study type: Interventional

Clinical and radiographic assessment of A-prf,A-prf combined with nanochitosan compared to chitosan for symptomatic irreversible pulpits in lower permanent first molar

NCT ID: NCT06437366 Recruiting - Substance Abuse Clinical Trials

Nurse-Led Heart Math Training Program With Substance Use Disorder

HeartMathsub
Start date: July 1, 2024
Phase: N/A
Study type: Interventional

Substance use disorders (SUDs) pose significant challenges to individuals' psychological well-being, resilience, and emotional adjustment. These disorders often lead to detrimental effects on physical health, mental health, and overall quality of life, creating a critical need for effective interventions that can support recovery and enhance emotional resilience. One promising approach is the implementation of nurse-led HeartMath training programs. These programs utilize evidence-based techniques to improve emotional regulation, increase resilience, and foster a sense of coherence, which is the ability to perceive life as comprehensible, manageable, and meaningful.

NCT ID: NCT06437236 Recruiting - Clinical trials for Hemodynamic Instability and Shivering

Comparative Study Between Intravenous Granisetron and Ondansetron on Their Effect on Hemodynamics and Shivering After Spinal Anesthesia in Elective Cesarean Delivery

Start date: April 10, 2024
Phase: N/A
Study type: Interventional

Spinal anesthesia is commonly used in cesarean section surgeries . The most important adverse effects of spinal anesthesia are hypotension and bradycardia caused by sympathetic blockade, with an incidence of about 55-100% . However, blocking the venous return by the gravid uterus increases the risk of hypotension. Spinal anesthesia-induced hypotension is commonly associated with uncomfortable symptoms, such as shivering , nausea and vomiting, in the mother. Prolonged maternal hypotension may lead to serious maternal adverse effects, such as cardiovascular collapse, loss of consciousness, apnea, and aspiration of gastric contents. In addition, uteroplacental blood flow decreases in cases of sustained hypotension and detrimental neonatal effects, such as fetal acidosis and fetal death, may occur. Preventing spinal anesthesia-induced hypotension during cesarean section is essential for the well-being of both the mother and neonate. Also, Shivering often happens after spinal anesthesia. Shivering is an unconscious and rhythmic movement involving several groups of muscles. The increase of muscle activity generates the elevation of oxygen consumption, lactic acidosis, and carbon dioxide production In recent years, researchers have focused on the effects of the Bezold-Jarisch reflex (BJR) . This reflex includes a triad of bradycardia, hypotension, and apnea. Researchers have suggested that serotonin and 5-hydroxytryptamine 3 (5-HT3) receptors play an important role in the occurrence of the BJR after spinal anesthesia . The 5-HT3 receptors are present in the heart, lung, and spine. Diminished venous return caused by spinal anesthesia stimulates the cardiac chemoreceptors, and parasympathetic activity increases, which results in bradycardia and hypotension . Studies have suggested that the use of 5-HT3 antagonists may attenuate spinal anesthesia-induced hypotension, thus inhibiting peripheral vasodilatation, alleviating the BJR, and increasing venous return to the heart . Ondansetron is a commonly used 5-HT3 receptor antagonist, and its peak plasma concentration occurs within 30 min following IV injection. Granisetron is a new 5-HT3 receptor antagonist, and the onset of action occurs 30 min following its IV administration [

NCT ID: NCT06435780 Recruiting - Clinical trials for Defect in Alveolar Ridge

Novel Technique Versus Conventional Subepithelial Connective Tissue Graft in Treatment of Ridge Contour Defects

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to clinically and radiographically evaluate and compare two techniques to augment soft tissues: the conventional subepithelial connective tissue graft technique and a novel denuded interpositional pedicled rolled flap technique (DIPRF) These techniques will be used to augment edentulous ridges that are recommended for rehabilitation by an implant or a fixed restoration.