Clinical Trials Logo

Pulpitis - Irreversible clinical trials

View clinical trials related to Pulpitis - Irreversible.

Filter by:

NCT ID: NCT06330519 Completed - Clinical trials for Pulpitis - Irreversible

Impact of Different Techniques on The Efficacy of Anaesthesia in Mandibular Molars With Acute Irreversible Pulpitis

Start date: September 25, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to assess the effect of - Preoperative intraligamentary corticosteroids injection - Cryotherapy which is cold application on : - Hard tooth structure ( crown of the tooth ) - Soft tissue overlying roots on the efficacy of the inferior alveolar nerve block anaesthesia in patients with mandibular molars with symptomatic irreversible pulpitis. The main question it aims to answer are: • Does intraligamentary dexamethazone injection increase the success rate of inferior alveolar nerve block without the need for oral premedication. Participants will describe their preoperative pain level to the investigator and describe their pain level during the treatment. Researchers will compare cryotherapy to see if it increases the success rate of inferior alveolar nerve block.

NCT ID: NCT06268912 Completed - Clinical trials for Pulpitis - Irreversible

Cryoanalgesia for Irreversible Pulpitis

CryPain
Start date: September 7, 2022
Phase: N/A
Study type: Interventional

The aim of the present study was to evaluate the effectiveness of pulpal anesthesia in pain control during endodontic treatment by lowering the temperature of the injected plain 3% cold Mepivacaine (5ºC) compared to 3% Mepivacaine at room temperature in teeth with irreversible pulpitis.

NCT ID: NCT06201871 Recruiting - Clinical trials for Pulpitis - Irreversible

Effect of Alcohol Consumption on the Success Rates

Start date: January 2, 2024
Phase: N/A
Study type: Interventional

This prospective, randomized, double-blind clinical trial will be carried out Conservative Dentistry, Faculty of Dentistry, Jamia Millia Islamia. Seventy adult patients (35 alcoholic and 35 non-alcoholics) with symptomatic irreversible pulpits in a mandibular first or second molar will receive an IANB with 2% lidocaine. In case of pain during treatment, the procedure will be stopped, and the patients will be asked to rate the pain on the Heft-Parker scale. The injection shall be considered as successful if the patient reports pain scores less than 55 on the HP scale.

NCT ID: NCT06146686 Not yet recruiting - Clinical trials for Pulpitis - Irreversible

Single Rotary File Pulpectomy in Primary Molars

Start date: February 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare the clinical effectiveness of a single rotary file system versus a multiple rotary files system in pulpectomy of primary molars

NCT ID: NCT06088446 Completed - Clinical trials for Pulpitis - Irreversible

Effect of Intrapulpal Injections on the Post-endodontic Pain

Start date: July 5, 2023
Phase: N/A
Study type: Interventional

To achieve painless treatment in patients with a failed primary IANB, supplementary anesthesia has been advised. The majority of the studies evaluating intrapulpal injections have been performed on asymptomatic teeth. Very limited research has been dedicated to the evaluation of different variables in intrapulpal injections in patients with symptomatic irreversible pulpitis. The aim of this study was to evaluate postoperative pain after an intrapulpal anesthesia injection given after a failed inferior alveolar nerve block (IANB), in patients with symptomatic irreversible pulpitis. This prospective, randomized, double-blind clinical trial was carried out at the Department of Conservative Dentistry and Endodontics, Faculty of Dentistry, Jamia Millia Islamia. One hundred and eight adult patients, with symptomatic irreversible pulpits in a mandibular first or second molar received an initial IANB with 2% lidocaine. Pain during the endodontic treatment was assessed using a visual analog scale (VAS). Patients experiencing pain on endodontic intervention were randomly allocated to one of the two treatment groups: one group received a supplementary intrapulpal injection while the other received a supplementary intraligamentary injection The presence of postoperative pain was assessed at 1, 2, 3, and 7 days after treatment.

NCT ID: NCT06002698 Recruiting - Clinical trials for Pulpitis - Irreversible

Full Pulpotomy Versus Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis

Start date: August 8, 2023
Phase: N/A
Study type: Interventional

Background The European Society of Endodontology (ESE) and the American Association of Endodontists (AAE) position statements on the management of deep caries and exposed pulp recommended adoption and promotion of strategies aimed at preserving the pulp, but also acknowledged the need for well-designed and adequately powered randomised control trials to provide the evidence needed to support vital pulp treatment (VPT) and change clinical practice. Objectives 1. To undertake a randomised controlled clinical trial comparing full pulpotomy with root canal treatment for mature maxillary and mandibular posterior teeth with signs and symptoms indicative of irreversible pulpitis and normal apical tissues in adults. 2. Undertake a cost-effectiveness analysis to examine the potential long-term costs and benefits of pulpotomy. 3. Undertake a process evaluation to assess the acceptability of the intervention to both dentists and patients, while exploring the barriers and enablers to implementation.

NCT ID: NCT05964933 Enrolling by invitation - Clinical trials for Pulpitis - Irreversible

Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis

Start date: July 11, 2023
Phase: N/A
Study type: Interventional

This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e. signs and symptoms indicative of irreversible pulpitis) conducted at the National University Centre for Oral Health Singapore (NUCOHS) Endodontic unit. Up to 70 teeth, 35 in each group, will be enrolled. Clinical and radiographic outcome data will be collected and analysed, and a parallel cost-effectiveness analysis will also be undertaken to examine the potential costs and benefits of pulpotomy. A process evaluation will also be conducted to assess the acceptability of the intervention to both dentists and patients, while exploring the barriers and enablers to implementation.

NCT ID: NCT05928611 Not yet recruiting - Clinical trials for Pulpitis - Irreversible

Intraligmentary Dexamethasone in Lower First Molars With Irreversible Pulpitis and Apical Periodontits

Start date: August 2023
Phase: N/A
Study type: Interventional

Using intraligmentary dexamethasone to reduce the pain intensity during and after root canal preparation

NCT ID: NCT05923619 Completed - Post-operative Pain Clinical Trials

Evaluation of Post-operative Pain After Total Pulpotomy and Root Canal Treatment

Start date: October 13, 2022
Phase: N/A
Study type: Interventional

The aim of this study was to compare post-operative pain following total pulpotomy (TP) and root canal treatment (RCT) in mature molar teeth with severe symptoms indicative of irreversible pulpitis. To compare the traditional pulpitis classification with the Wolters system in evaluating post-operative pain. Materials and Methods: Sixty-four mature mandibular molar with symptomatic vital pulps in patients aged 18-60 years were included and were classified according to the Wolters (moderate/severe pulpitis) and the traditional pulpitis classification (reversible/irreversible pulpitis). The teeth randomly divided into 2 groups. RCT was performed, using standardized protocols. TP was performed to the level of the canal orifices, and haemostasis was achieved with 2.5% NaOCl. 3 mm layer of MTA was placed as the pulpotomy agent. The treated teeth were restored with glass ionomer cement followed by composite. Pain was recorded 6, 12, 24, 48, 72 hours and 7 days after treatment. The data collected were statistically analyzed

NCT ID: NCT05904184 Completed - Pain, Postoperative Clinical Trials

Comparison of Calcium Silicate-based Sealer and Epoxy Resin-based Sealer

Start date: June 1, 2020
Phase: Phase 3
Study type: Interventional

Background: Sealers have been concerned with obturation. However, studies for assessing the effectiveness of endodontic treatment of sealer based on Calcium Silicate have been not much. Objective: This study aimed to assess the effectiveness of endodontic treatment of sealer based on Calcium Silicate Methods: A prospective, single-blind, clinical trial was conducted from June 2020 to December 2020 with 42 irreversible pulpitis teeth by one clinician. The postoperative pain was assessed after root canal treatment using sealer based on Calcium Silicate and sealer based on Epoxy resin after 6 hours, 12 hours, 24 hours, 48 hours, 72 hours and 7 days and inconvenient symptoms were assessed after 7 days, 3 months and 6 months. t-test, Mann-Whitney and Wilcoxon analysis were applied. Key words: obturation, sealer based on Calcium Silicate and sealer based on Epoxy resin