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NCT ID: NCT03393962 Suspended - Ovarian Cancer Clinical Trials

Intervention of Ovarian Cancer With Antigen-specific Engineered Immune Effectors

Start date: December 1, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

This is a single-arm, open-label, phase I/II trial to evaluate the safety and efficacy of ovarian cancer-specific, engineered immune effectors (OC-EIEs) in women.

NCT ID: NCT03229876 Suspended - Clinical trials for Acute Lymphoblastic Leukemia (ALL)

Safety and Efficacy Evaluation of CD19-UCART

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of ascending doses of CD19-UCART in patients with relapsed or refractory B-cell hematological malignancies.

NCT ID: NCT03186456 Suspended - Cerebral Infarction Clinical Trials

The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ACI) in the Treatment of Acute Cerebral Infarction

Start date: December 31, 2024
Phase: Phase 1
Study type: Interventional

The purposes of the study is to determine the safety and efficacy of treating acute ischemic stroke patients with human umbilical cord mesenchymal stem cells (hUC-MSC).

NCT ID: NCT03184935 Suspended - Clinical trials for Myelodysplastic Syndromes

Research for Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-MDS) in the Treatment of Myelodysplastic Syndrome (MDS)

Start date: December 31, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purposes of the study is to determine the safety and efficacy of human umbilical cord mesenchymal stem cells (hUC-MSC) in treating Myelodysplastic Syndrome patients.

NCT ID: NCT03180463 Suspended - Clinical trials for Osteonecrosis of Femoral Head

The Study of Early Stage Osteonecrosis of Femoral Head With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ONFH)

Start date: December 31, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purposes of the study is to evaluate the safety and efficacy of human umbilical cord mesenchymal stem cells (hUC-MSC) in treating osteonecrosis of femoral head patients.

NCT ID: NCT03180450 Suspended - Heart Failure Clinical Trials

The Study of Heart Failure With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-HF)

Start date: December 31, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purposes of the study is to evaluate the safety and efficacy of human umbilical cord mesenchymal stem cells (hUC-MSC) in treating heart failure patients

NCT ID: NCT03176498 Suspended - Cerebral Infarction Clinical Trials

Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period.

Start date: December 31, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This is a randomized, double-blind study. Human umbilical cord mesenchymal stem cells (hUC-MSC) will be treated on cerebral infarction patients, and evaluates their neurological function of convalescent period.

NCT ID: NCT03172897 Suspended - Delirium Clinical Trials

Low-dose Dexmedetomidine in Mechanically Ventilated ICU Patients

Start date: August 20, 2017
Phase: Phase 4
Study type: Interventional

For patients undergoing mechanical ventilation, light sedation is better than deep sedation for the outcomes, which is manifested as shortened length of ICU stay, shortened duration of mechanical ventilation, and decreased mortality. In a recent study of the investigators, low-dose dexmedetomidine without sedative effects (0.1 ug/kg/h) improved sleep quality and reduced the incidence of delirium in elderly patients admitted to the ICU after surgery. The investigators hypothesize that, for ICU patients with prolonged mechanical ventilation, low-dose dexmedetomidine infusion (0.1 ug/kg/h) may also be effective in decreasing delirium. The purpose of this study is to investigate whether low-dose dexmedetomidine infusion can reduce the incidence of delirium in ICU patients with prolonged duration of mechanical ventilation (>= 24 hours).

NCT ID: NCT03163459 Suspended - Stroke, Acute Clinical Trials

Short-duration Selective Brain Cooling for Patients Undergoing Mechanical Thrombectomy

Start date: February 6, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

To determine the efficacy and safety of short-duration intra-artery selective brain cooling in addition to mechanical thrombectomy in patients with acute ischemic stroke.

NCT ID: NCT03130946 Suspended - Breast Neoplasms Clinical Trials

Comparison of Two Types of Biopsy in Suspicious Axillary Lymph Nodes

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

Axillary lymph node status is a vital prognostic factor in breast cancer patients and provides crucial information for making treatment decisions. Ultrasound test with subsequent fine needle aspiration (FNA) biopsy in nodes with suspicious features remains the standard of axillary lymph node workup. Insufficient sampling and limited diagnostic accuracy of cytological test compromise the outcome the preoperative lymph node staging strategy especially in patients with intermediate suspicious nodes. This prospective study is to compare the performance of a crpo-assisted core biopsy with FNA.