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NCT ID: NCT06289894 Not yet recruiting - Clinical trials for Advanced Solid Tumor

A Study of BRY805 in Participants With Advanced Solid Tumors

Start date: March 2024
Phase: Phase 1
Study type: Interventional

This is a phase 1 open label multicenter study to evaluate safety, tolerance and the maximum tolerance of BRY805 administered intravenously (IV) once every three weeks in participants with advanced solid tumors, so as to confirm the recommended phase 2 dose of BRY805 and obtain the preliminary efficacy information of participants with advanced solid tumors.

NCT ID: NCT06289751 Not yet recruiting - Cervical Cancer Clinical Trials

Neoadjuvant Chemoimmunotherapy and Extrafascial Hysterectomy for IB2 Cervical Cancer

Start date: March 1, 2024
Phase: Phase 2
Study type: Interventional

This study is an exploratory clinical trial to investigate the feasibility of neoadjuvant chemoimmunotherapy plus extrafascial hysterectomy and pelvic lymph node dissection in patients with stage IB2 (2018 FIGO) cervical cancer and to observe the response rate to treatment, adverse effects and complications, and to assess the survival rate of patients.

NCT ID: NCT06289517 Not yet recruiting - Neoplasms Clinical Trials

PET Imaging of 68Ga-Her2-affibody in Tumors With High Her2 Expression

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This project uses HER2 protein as the target group of radiodrugs to explore the diagnostic efficacy, safety and metabolic characteristics of 68Ga-Her2-affibody in the expression status of HER2, aiming to provide a new imaging method for the determination of HER2 status in breast cancer At the same time, it also provides new methods and means for early diagnosis, accurate staging, recurrence judgment, treatment decision-making and prognosis judgment of malignant tumors such as lung cancer, gastrointestinal cancer and bladder cancer, and provides scientific basis for precise treatment of malignant tumors.

NCT ID: NCT06289062 Not yet recruiting - Cervical Cancer Clinical Trials

Neoadjuvant Chemotherapy Plus Camrelizumab for FIGO Stage IB1 Cervical Cancer

Start date: March 1, 2024
Phase: Phase 2
Study type: Interventional

This multicenter, prospective clinical trial is designed to enroll PD-L1 expression-positive patients with stage IB1 cervical cancer who desire fertility preservation to undergo neoadjuvant chemotherapy in combination with a PD-1 inhibitor to evaluate the rate of complete pathologic remission, treatment-related adverse events, pregnancy rate, miscarriage rate, preterm birth rate, live birth rate, PFS and OS.

NCT ID: NCT06288893 Not yet recruiting - COVID-19 Clinical Trials

SHEN211 Tablets for the Treatment of Mild and Moderate Novel Corona Virus Infections (COVID-19)

Start date: April 1, 2024
Phase: Phase 2
Study type: Interventional

Randomized, double-blind, placebo-controlled, multicenter phase II clinical study of SHEN211 tablets

NCT ID: NCT06288373 Not yet recruiting - Cervical Cancer Clinical Trials

Neoadjuvant Chemoimmunotherapy Versus Concurrent Chemoradiotherapy for LACC

Start date: March 1, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

It is a prospective, open-label, randomized, controlled phase II/III clinical trial in which patients with PD-L1-positive FIGO stage IB3, IIA2 and IIB(tumors >4 cm in diameter)will be enrolled and randomly divided into the neoadjuvant chemoimmunotherapy plus surgery group and the CCRT group.

NCT ID: NCT06288360 Not yet recruiting - Cervical Cancer Clinical Trials

Neoadjuvant Immunochemotherapy in PD-L1-negative LACC

Start date: March 1, 2024
Phase: Phase 2
Study type: Interventional

This is a multicenter, prospective, single-arm, phase 2 clinical trial designed to evaluate the therapeutic efficacy of the NACI (neoadjuvant chemotherapy plus Camrelizumab) for PD-L1-negative locally advanced cervical cancer.

NCT ID: NCT06287970 Not yet recruiting - Chronic Prostatitis Clinical Trials

TaVNS Improves the Symptoms of Patients With Moderate to Severe CP/CPPS

Start date: March 15, 2024
Phase: N/A
Study type: Interventional

This trial aims to evaluate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) for moderate to severe chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). This study is a prospective, randomized, controlled trial. A total of 68 patients with CP/CPPS will be recruited. After baseline assessment, the patients will be randomized into taVNS group (n = 34) and sham-taVNS group (n = 34). The intervention of two group will last for 4 weeks with a 8-week follow-up period after the treatment. The National Institutes of Health chronic Prostatitis Symptom Score index (NIH-CPSI), International Prostate Symptom Score Scale (IPSS), European quality of Life-5 Dimensions Questionnaire (EQ-5D), self-rating anxiety Scale (SAS) and self-rating depression scale (SDS) will be assessed. The adverse events during the whole study will be recorded detailedly.

NCT ID: NCT06287567 Not yet recruiting - Clinical trials for Immune Thrombocytopenia

Lusutrombopag in the Treatment of Immune Thrombocytopenia (ITP)

Start date: March 20, 2024
Phase: Phase 4
Study type: Interventional

This exploratory study is to investigate the efficacy, safety and tolerability of Lusutrombopag in the treatment of primary immune thrombocytopenia in Chinese patients who have failed first-line therapy

NCT ID: NCT06287385 Not yet recruiting - Healthy Children Clinical Trials

An Exploratory RWE Study Exploring Effects of a Goat Milk Based Young Child Formula on Health Benefits

Start date: May 15, 2024
Phase: N/A
Study type: Interventional

This is an exploratory real-world study designed to gain insight into the role of the product in terms of health benefits in toddlers, with the potential to generate hypotheses on key and other exploratory objectives.