Lusutrombopag in the Treatment of Immune Thrombocytopenia (ITP)

Status Not yet recruiting

Clinical Trial Summary

This exploratory study is to investigate the efficacy, safety and tolerability of Lusutrombopag in the treatment of primary immune thrombocytopenia in Chinese patients who have failed first-line therapy

Clinical Trial Description

This is an open-label, single-arm study of lusutrombopag initiated at a dose of 3mg daily titrated to a maximum dose of 6mg daily in the treatment of Chinese adults with persistent or chronic Immune thrombocytopenia (ITP) with or without prior splenectomy after failing first line therapy such corticosteroids and IV immunoglobulin. The study consists of three phases: Screening, Core Study（participants are treated with lusutrombopag 3mg daily for 4 weeks), and Titration study (participants are treated with lusutrombopag titrated to a maximum dose of 6mg daily according to their platelet counts ;

Study Design

Related Conditions & MeSH terms

Idiopathic Thrombocytopenic Purpura
Immune Thrombocytopenia
Purpura
Purpura, Thrombocytopenic
Purpura, Thrombocytopenic, Idiopathic
Thrombocytopenia

Clinical Trial Details

NCT number	NCT06287567
Study type	Interventional
Source	Institute of Hematology & Blood Diseases Hospital, China
Contact	Liu Xiaofan
Phone	+8602223909240
Email	liuxiaofan@ihcams.ac.cn
Status	Not yet recruiting
Phase	Phase 4
Start date	March 20, 2024
Completion date	November 30, 2024

View Details

See also
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