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NCT ID: NCT05738460 Active, not recruiting - Healthy Clinical Trials

Effects of IAP-EOGBSD on Offspring's Gut Microbiome and Immunity.

Start date: February 23, 2022
Phase:
Study type: Observational

This study is planned to be recruited in two hospitals in South China, Zhujiang Hospital of Southern Medical University and Zhongshan Boai Hospital Recruit participants, plan to recruit obstetrics and child health departments in study hospitals, meet inclusion and discharge criteria 1~3 infants, a total of 360, recruited by Pearl River Hospital of Southern Medical University and Zhongshan Boai Hospital 180 people each.

NCT ID: NCT05738083 Active, not recruiting - Clinical trials for Aneurysmal Subarachnoid Hemorrhage

Prediction Models for Complications, Disability, and Death in Patients With Aneurysmal Subarachnoid Hemorrhage

Start date: October 1, 2018
Phase:
Study type: Observational [Patient Registry]

This study aims to prospectively collect the clinical and radiogical features to investigate the associations between the potential risk factors and secondary complications, adverse long-term functional outcomes, and death in patients with aneurysmal subarachnoid haemorrhage (aSAH).

NCT ID: NCT05735652 Active, not recruiting - Prostate Cancer Clinical Trials

An Observational Study of Radiotherapy After Injection of SpaceOAR Hydrogel

Start date: November 3, 2022
Phase:
Study type: Observational [Patient Registry]

This observational study aims to evaluate the safety and effectiveness of radiotherapy for subjects with localized T1-T2 prostate cancer in China who were injected with SpaceOAR Hydrogel, via collecting clinical data related to radiotherapy.

NCT ID: NCT05735132 Active, not recruiting - Clinical trials for Efficiency and Safey of Radial Artery Cannulation

Novel Local Infiltration Anesthesia for Radial Artery Cannulation.

Start date: February 5, 2023
Phase: N/A
Study type: Interventional

This clinical trial aims to compare the pain scores and cannulation success rates of conventional, bar-shaped, and V-shaped local infiltration anesthesia in participants' radial artery cannulation. The main questions it aims to answer are: - Are bar-shaped and V-shaped more successful than the conventional block in radial artery cannulation? - Are bar-shaped and V-shaped less painful than the conventional block in radial artery cannulation? Participants will describe their pain score during their radial artery cannulation. Researchers will compare the pain scores and cannulation success rates in bar-shaped, V-shaped, and conventional line blocking to see if bar-shaped and V-shaped blocking is better choices than conventional line blocking.

NCT ID: NCT05735054 Active, not recruiting - Thyroid Diseases Clinical Trials

A Novel Technique for Endoscopic Transaxillary Thyroidectomy Comparison

Start date: January 1, 2021
Phase:
Study type: Observational

The clinical data from all except the first 20 cases who underwent our novel transaxillary thyroidectomy were collected retrospectively, while the data from patients who underwent conventional open thyroid lobectomy by same surgeon during the same period were used as a control.

NCT ID: NCT05735041 Active, not recruiting - Clinical trials for Mild Cognitive Impairment

Computerized Cognitive Training in Patients With Coronary Heart Disease and Mild Cognitive Impairment

COG-T CHD
Start date: January 18, 2023
Phase: N/A
Study type: Interventional

In this study, a multicentre, double-blind, randomized controlled study based on cognitive training was conducted in patients with coronary heart disease and cognitive impairment but without dementia, to evaluate the effectiveness of computer-based digital therapy in improving the cognitive function of such patients.

NCT ID: NCT05734807 Active, not recruiting - Clinical trials for Chronic HBV Infection

A Study to Evaluate the Antiviral Activity and Safety of HH-003 in Chronic Hepatitis B Subjects With Low-level Viremia

Start date: July 20, 2022
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, controlled Phase IIa study of HH-003 to evaluate the antiviral activity and safety in nucleos(t)ide analogues-treated chronic hepatitis B subjects with low-level viremia. HH-003 is a human monoclonal antibody targeting the pre-S1 domain of the HBV large envelope protein. It blocks engagement of preS1 with sodium taurocholate co-transporting polypeptide (NTCP), the cellular receptor for HBV.

NCT ID: NCT05732441 Active, not recruiting - Prostatitis Clinical Trials

Therapeutic Study of Prostatitis With Elevated PSA

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

This clinical study was mainly aimed at exploring the efficacy of herbal medicine (Huange Capsule) in the treatment of patients with prostatitis with elevated PSA. The main questions it aims to answer are: 1. To evaluate the influence and exact curative effect of huange capsule on serum PSA level of patients with PSA-elevated prostatitis, to improve the specificity of PSA and reduce unnecessary puncture biopsy. 2. To provide evidence-based evidence for clinical efficacy evaluation Subjects will be randomized to a routine regimen with or without the use of Huangge capsules. To evaluate whether the efficacy of the conventional treatment combined with Huange capsule group was superior to that of the conventional medication group.

NCT ID: NCT05732428 Active, not recruiting - Breast Cancer Clinical Trials

A Study to Learn About the Study Medicine (Called ARV-471) in People With ER+/HER2- Advanced BC in China

Start date: February 20, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this clinical trial is to learn about the pharmacokinetics. safety and tolerability of the study medicine (called ARV-471) for the potential treatment of advanced estrogen receptor postive and human epidermal growth factor receptor 2 negative breast cancer. This study is seeking participants have - ER+/HER2- advanced breast cancer - received at least 1 line of endocrine therapy with or without CDK4/6 inhibitor - received up to 2 prior regimens of chemotherapy for advanced setting. All participants in this study will receive ARV-471. ARV-471 will be given by mouth at home once a day. The experiences of people receiving the study medicine will be examined. This will help determine if the study medicine is safe and effective. Participants will take part in this study until their cancer is no longer responding. During this time, they will have visits at the study clinic about every 4 weeks.

NCT ID: NCT05731752 Active, not recruiting - Clinical trials for Advanced Solid Tumors

Study on the Tolerability and Pharmacokinetics of HX009 in Patients With Advanced Solid Tumors

Start date: June 4, 2020
Phase: Phase 1
Study type: Interventional

This is an open, multi-dose administration dose exploratory clinical phase I study to evaluate the safety, tolerability, and PK characteristics of HX009 injection in patients with advanced solid tumors and to initially measure its antitumor efficacy.