Clinical Trials Logo
  1. Home
  2. Coronary Heart Disease
  3. NCT00382551
  4. Details
NCT00382551 Clinical Trial

The Effect of Beer, Red Wine and Fruit Juice on Blood Vessel Function in Persons With Cardiovascular Disease

Coronary Heart Disease Clinical Trial

Official title:
The Effect of Alcohol and Polyphenolic Compounds on Endothelial Function

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00382551
Other study ID # VN-20060043
Secondary ID
Status Completed
Phase Phase 0
First received September 28, 2006
Last updated January 29, 2009
Start date October 2006

Study information
Verified date January 2009
Source Aalborg Universitetshospital
Contact n/a
Is FDA regulated No
Health authority Denmark: National Board of HealthDenmark: Ethics Committee
Study type Interventional

Clinical Trial Summary

To study the effect of red wine, beer and fruit juice on endothelial function in patients with coronary Heart disease.

Recruitment information / eligibility
Status Completed
Enrollment 49
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 30 Years to 80 Years
Eligibility Inclusion Criteria:

- Men or postmenopausal women with stable coronary heart disease

- Coronary heart disease should be verified by coronary angiography with at least 50% stenosis in at least one coronary vessel.

Exclusion Criteria:

- Patients with myocardial infarction within the last tree months

- Persons with a present or earlier alcohol abuse

- Persons with a present or earlier drug abuse

- Person with malign disease

- Persons, that we consider unsuitable to carry through the examines.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Intervention

Behavioral:
• Moderate daily consumption of Red wine

• Moderate daily consumption of beer

• Moderate consumption of fruit juice rich in polyphenolics

Locations
Country Name City State
Denmark Department of Cardiology, Aalborg Hospital, Science and Innovation Center Aalborg

Sponsors (1)
Lead Sponsor Collaborator
Aalborg Universitetshospital

Country where clinical trial is conducted

Denmark, 

Outcome
Type Measure Description Time frame Safety issue
Primary Changes in flow-mediated vasodilation after 2 weeks intervention compared with baseline
Secondary Lipid status after 2 weeks intervention compared with baseline
Secondary Effects in Coagulation factors after 2 weeks intervention
Secondary Effects on markers of inflammation after 2 weeks intervention
Secondary Effects on markers of endothelial function after 2 weeks intervention
Secondary Changes in the overall antioxidant activity in plasma after 2 weeks intervention
See also
  Status Clinical Trial Phase
Recruiting NCT05196659 - Collaborative Quality Improvement (C-QIP) Study N/A
Completed NCT05088291 - Application of a New X-ray Protective Device in Coronary Interventional Therapy
Completed NCT03076801 - Does Choral Singing Help imprOve Stress in Patients With Ischemic HeaRt Disease? N/A
Completed NCT04584645 - A Digital Flu Intervention for People With Cardiovascular Conditions N/A
Not yet recruiting NCT04995159 - Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVas™ BRS System N/A
Recruiting NCT02967718 - Innovation Research of Differentiation and Treatment Methods Based on CHD Phlegm and Blood Stasis Syndrome N/A
Completed NCT02888652 - Study on the Registration of Coronary Heart Disease Patients Undergoing PCI
Completed NCT02163044 - The Hellenic Postprandial Lipemia Study (HPLS)
Terminated NCT02045134 - Supplementation With Polyphenol-Rich Foods and Atrial Fibrillation After a Cardiac Surgery N/A
Active, not recruiting NCT02244853 - Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease N/A
Completed NCT01826552 - Comparison of the Angiographic Result of the Orsiro Hybrid Stent With Resolute Integrity Stent Phase 4
Completed NCT02440893 - Understanding the Effect of Metformin on Corus CAD (or ASGES)
Completed NCT01920009 - Impact of Motivational Interviews Within Pharmacy Care Upon Adherence to Cardiovascular Medicines N/A
Terminated NCT01906957 - Cognition and Exercise Training N/A
Completed NCT02753829 - Home-based Cardiovascular Rehabilitation, Maintenance Phase, in Subjects With Coronary Artery Disease N/A
Recruiting NCT01689688 - Healing Response to Everolimus-eluting Stent Implantation; Serial Assessment With opticaL Coherence Tomography N/A
Completed NCT01779401 - Clopidogrel Response Evaluation and AnTi-Platelet InterVEntion in High Thrombotic Risk PCI Patients N/A
Recruiting NCT01462799 - COR-PRIM: Problem-based Learning (PBL) After Coronary Heart Disease (CHD) - Long-term Evaluation in Primary Care of Self-care N/A
Recruiting NCT01456364 - Intracoronary Stenting and Antithrombotic Regimen: ADjusting Antiplatelet Treatment in PatienTs Based on Platelet Function Testing Phase 4
Completed NCT01428947 - Does Coronary Angiography Cause Cognitive Dysfunction? N/A